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Distinct Neurochemical Signature of Mindfulness and Progressive Muscle Relaxation in limbic regions: a randomized controlled MR spectroscopy study

Research Square November 13, 2025 preprint DOI: 10.21203/rs.3.rs-7722934/v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Randomized controlled trial
Intervention Progressive muscle relaxation
Duration Single session
Topics Meditation
Key findings Mindfulness meditation and progressive muscle relaxation produce opposite neurochemical changes in the anterior cingulate cortex: mindfulness increases Glx and decreases GABA, while progressive muscle relaxation decreases Glx and increases GABA.

Abstract

Distinct Neurochemical Signature of Mindfulness and Progressive Muscle Relaxation in limbic regions: a randomized controlled MR spectroscopy study