Nature Medicine
June 3, 2025
Chloé Pronovost-Morgan, Kyle T. Greenway, Leor Roseman et al.
26 citations
Psychedelic substances exhibit complex interactions with the 'set and setting' of use, that is, the mental state of the user and the environment in which a psychedelic experience takes place. Despite these contextual variables' known importance, psychedelic research has lacked methodological rigor in reporting extra-pharmacological factors. This study aimed to generate consensus-based...
Contemporary Buddhism
April 22, 2025
Nicholas K. Canby, Jared R. Lindahl, David J. Cooper et al.
1 citation
Although meditation is often treated as an individual practice, meditation teachers can play an important role. Drawing on the mixed-methods dataset of the Varieties of Contemplative Experience project, this paper examines the role of meditation teachers and their impacts on Western practitioners who are navigating meditation-related challenges. Quantitative and qualitative results from 68...
PLoS One
2025
Nicholas K. Canby, Elizabeth A Cosby, Roman Palitsky et al.
10 citations
Within mindfulness-based programs (MBPs), mixed results have been found for the role of childhood trauma as a moderator of depression outcomes. Furthermore, childhood trauma and PTSD symptoms have been identified as possible risk factors for the occurrence of meditation-related adverse effects (MRAE). The present research examined multiple forms of childhood trauma and PTSD symptoms as...
International review of psychiatry (Abingdon, England)
December 1, 2024
Roman Palitsky, Nicholas K. Canby, Nicholas T. van Dam et al.
6 citations
Psychedelics have shown early evidence for a range of benefits and low harm profiles in extant research. However, adverse effects (AEs) research in psychedelics has been limited, leading to underspecified AE profiles, inconsistent measurement, and potential undercounting of AEs. The development of safe, effective psychedelic therapies and treatments for AEs when they occur requires a thorough...
Consciousness and Cognition
March 1, 2024
Nicholas K. Canby, Jared R. Lindahl, Willoughby B. Britton et al.
11 citations
Mystical experience, non-dual awareness, selflessness, self-transcendent experience, and ego-dissolution have become increasingly prominent constructs in meditation and psychedelic research. However, these constructs and their measures tend to be highly overlapping, imprecise, and poorly integrated with similar pathological experiences. The present study seeks to clarify the common factors...
Frontiers in Psychology
November 22, 2021
Willoughby B. Britton, Gaelle Desbordes, Rebecca L. Acabchuk et al.
77 citations
Self-related processes (SRPs) have been theorized as key mechanisms of mindfulness-based interventions (MBIs), but the evidence supporting these theories is currently unclear. This evidence map introduces a comprehensive framework for different types of SRPs, and how they are theorized to function as mechanisms of MBIs (target identification). The evidence map then assesses SRP target...
Clinical psychological science : a journal of the Association for Psychological Science
May 18, 2021
Willoughby B. Britton, Jared R. Lindahl, David J. C. Cooper et al.
Research on the adverse effects of mindfulness-based programs (MBPs) has been sparse and hindered by methodological imprecision. The 44-item Meditation Experiences Interview (MedEx-I) was used by an independent assessor to measure meditation-related side effects (MRSEs) following three variants of an 8-week program of mindfulness-based cognitive therapy (n = 96). Each item was queried for...