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Til Wykes

8 papers in the library · 408 citations · publishing 2011-2024

Papers

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Social influences on the relationship between dissociation and psychotic-like experiences.

Psychological Medicine June 3, 2024 Charles Heriot-Maitland, Til Wykes, Emmanuelle Peters

Background: Shame is experienced as a threat to social self, and so activates threat-protective responses. There is evidence that shame has trauma-like characteristics, suggesting it can be understood within the same conceptual framework as trauma and dissociation. Evidence for causal links among trauma, dissociation, and psychosis thus warrant the investigation of how shame may influence...

DOI: 10.1017/s0033291724001405 (opens in new tab) Full text (opens in new tab) Dissociation Psychosis Shame Social mechanisms +1

Metacognition and psychosis-spectrum experiences: A study of objective and subjective measures.

Schizophrenia Research January 14, 2023 Emma Palmer‐cooper, Abigail C. Wright, Nicola Mcguire et al.

Background: Metacognition refers to appraising one's thoughts and behaviours. Deficits in metacognition are associated with psychosis-spectrum experiences, such as hallucinations and delusions, in both clinical and non-clinical populations. Assessments of metacognitive function and abilities in clinical populations often vary in administration duration, and subjectivity of scores. This study...

DOI: 10.1016/j.schres.2022.12.014 (opens in new tab) Full text (opens in new tab) Humans Hallucinations Retrospective studies Cross-sectional studies +5

Detecting anomalous experiences in the community: The Transpersonal Experiences Questionnaire ( TEQ )

Psychology and Psychotherapy Theory Research and Practice January 9, 2023 Charlie Heriot-Maitland, Silia Vitoratou, Emmanuelle Peters et al. 7 citations

OBJECTIVES: There is growing recognition of the value of researching anomalous experiences in the general population to aid our understanding of the psychosis continuum. There are key differences in aims, foci and epistemologies of existing measures, with varying utility for specific research designs. This study addresses gaps in the literature by developing a measure of anomalous experiences...

Ketamine treatment for depression: qualitative study exploring patient views

BJPsych Open 2021 Sagar Jilka, Clarissa Mary Odoi, Emma Wilson et al.

Background Ketamine is a new and promising treatment for depression but comes with challenges to implement because of its potential for abuse. Aims We sought the views of patients to inform policy and practical decisions about the clinical use of ketamine before large-scale roll-out is considered. Method This qualitative study used three focus groups and three validation sessions from 14...

Exploring patients’ and carers’ views about the clinical use of ketamine to inform policy and practical decisions: mixed-methods study

BJPsych Open July 29, 2019 Sagar Jilka, Claire A. Murray, Ania M. Wieczorek et al. 20 citations

BACKGROUND: Only one-third of patients with major depressive disorder achieve remission. One new and promising treatment, ketamine, may prove challenging to implement because of its abuse potential. Although clinicians' views have been sought, we need patients' views before large scale roll-out is considered. AIMS: To explore patients' and carers' views to inform policy and practical decisions...

Liberal Acceptance Bias, Momentary Aberrant Salience, and Psychosis: An Experimental Experience Sampling Study

Schizophrenia Bulletin August 6, 2018 Ulrich Reininghaus, Margaret Oorschot, Steffen Moritz et al. 33 citations

Cognitive models of psychosis posit that reasoning biases are an important mechanism contributing to the formation of psychotic symptoms, in part through transforming anomalous experiences of aberrant salience into frank psychotic symptoms. This study aimed to investigate the interplay of liberal acceptance (LA) bias, which is a specific type of reasoning bias, and momentary aberrant salience...

Stress Sensitivity, Aberrant Salience, and Threat Anticipation in Early Psychosis: An Experience Sampling Study

Schizophrenia Bulletin February 1, 2016 Ulrich Reininghaus, Matthew J. Kempton, Lucia Valmaggia et al. 315 citations

While contemporary models of psychosis have proposed a number of putative psychological mechanisms, how these impact on individuals to increase intensity of psychotic experiences in real life, outside the research laboratory, remains unclear. We aimed to investigate whether elevated stress sensitivity, experiences of aberrant novelty and salience, and enhanced anticipation of threat contribute...

Does Change in Cannabis Use in Established Psychosis Affect Clinical Outcome?

Schizophrenia Bulletin October 29, 2011 Christine Barrowclough, Richard A Emsley, Emily Eisner et al. 33 citations

BACKGROUND: Cannabis use has been identified as a potent predictor of the earlier onset of psychosis, but meta-analysis has not indicated that it has a clear effect in established psychosis. AIM: To assess the association between cannabis and outcomes, including whether change in cannabis use affects symptoms and functioning, in a large sample of people with established nonaffective psychosis...