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Martin P. Paulus

7 papers in the library · 772 citations · publishing 2005-2025

Papers

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Posterior cingulate cortex downregulation training using fMRI neurofeedback in adolescents with early life adversity exposure: a randomized, single-blind trial.

Translational Psychiatry July 13, 2025 Xiaoqian Yu, Aki Tsuchiyagaito, Masaya Misaki et al. 4 citations

Early life adversity (ELA) disrupts default mode network (DMN) integrity subserving self-referential processes involved in emotional awareness and regulation. Mindfulness training (MT) reduces self-referential processing and down-regulates the DMN. We employed neurofeedback-augmented mindfulness training (NAMT), combining a core mindfulness strategy (focusing on breath) with real-time fMRI...

Augmenting mindfulness training through neurofeedback: a pilot study of the pre-post changes on resting-state functional connectivity in typically developing adolescents.

Frontiers in Neuroscience 2024 Kelly T Cosgrove, Aki Tsuchiyagaito, Zsofia P Cohen et al. 3 citations

Mindfulness training has been shown to promote positive mental health outcomes and related changes in neural networks such as the default mode network, which has a central node in the posterior cingulate cortex (PCC). Previous work from our group reported on the impact of a novel, neurofeedback augmented mindfulness training (NAMT) task on regulation of PCC hemodynamic activity in typically...

Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects

Frontiers in Pharmacology July 13, 2022 Patrick Vizeli, Isabelle Straumann, Urs Duthaler et al. 43 citations

Background: 3,4-Methylenedioxymethamphetamine (MDMA) has shown initial promise as an adjunct in psychotherapy to treat posttraumatic stress disorder (PTSD). Its efficacy and safety have been demonstrated across phase I–III studies. However, the mechanism underlying the potential utility of MDMA to treat PTSD in humans has not yet been thoroughly investigated. Preliminary evidence suggests that...

Self-regulation of the posterior cingulate cortex with real-time fMRI neurofeedback augmented mindfulness training in healthy adolescents: A nonrandomized feasibility study

Cognitive Affective & Behavioral Neuroscience March 15, 2022 Namik Kirlic, Zsofia P Cohen, Aki Tsuchiyagaito et al. 29 citations

Mindfulness training (MT) promotes the development of one's ability to observe and attend to internal and external experiences with objectivity and nonjudgment with evidence to improve psychological well-being. Real-time functional MRI neurofeedback (rtfMRI-nf) is a noninvasive method of modulating activity of a brain region or circuit. The posterior cingulate cortex (PCC) has been hypothesized...

Taking the body off the mind: Decreased functional connectivity between somatomotor and default‐mode networks following Floatation‐REST

Human Brain Mapping April 9, 2021 Obada Al Zoubi, Masaya Misaki, Jerzy Bodurka et al. 39 citations

Abstract Floatation‐Reduced Environmental Stimulation Therapy (REST) is a procedure that reduces stimulation of the human nervous system by minimizing sensory signals from visual, auditory, olfactory, gustatory, thermal, tactile, vestibular, gravitational, and proprioceptive channels, in addition to minimizing musculoskeletal movement and speech. Initial research has found that Floatation‐REST...

Interoception, contemplative practice, and health

Frontiers in Psychology June 9, 2015 Norman A. S. Farb, Jennifer Daubenmier, Cynthia Price et al. 630 citations

Interoception can be broadly defined as the sense of signals originating within the body. As such, interoception is critical for our sense of embodiment, motivation, and well-being. And yet, despite its importance, interoception remains poorly understood within modern science. This paper reviews interdisciplinary perspectives on interoception, with the goal of presenting a unified perspective...

MDMA affects both error-rate dependent and independent aspects of decision-making in a two-choice prediction task

Journal of Psychopharmacology June 27, 2005 Franz X. Vollenweider, Matthias E. Liechti, Martin P. Paulus 24 citations

Decision-making, i.e. selecting an action from a number of alternatives when the outcome is uncertain, is a complex process that is important for everyday life. 3,4-Methylenedioxymethamphetamine (MDMA), also known as 'Ecstasy', is a widely used recreational drug that is known to increase serotonin (5-HT) and, to a lesser extent, dopamine (DA) in animals. This study examined whether MDMA alters...