Adesh University Journal of Medical Sciences & Research
September 25, 2025
Rakesh Garg, Gurmeet Kaur Brar, Manpreet K. Singh
This case report describes the management of a 38-year-old female with recurrent depressive disorder, who presented with severe depressive symptoms and active suicidal ideations. She reported persistent low mood, loss of interest in pleasurable activities, fatigue, and disturbed sleep for nearly three weeks, with recurrent thoughts of ending her life in the preceding week. Despite being on...
Translational Psychiatry
July 13, 2025
Xiaoqian Yu, Aki Tsuchiyagaito, Masaya Misaki et al.
4 citations
Early life adversity (ELA) disrupts default mode network (DMN) integrity subserving self-referential processes involved in emotional awareness and regulation. Mindfulness training (MT) reduces self-referential processing and down-regulates the DMN. We employed neurofeedback-augmented mindfulness training (NAMT), combining a core mindfulness strategy (focusing on breath) with real-time fMRI...
Frontiers in Neuroscience
2024
Kelly T. Cosgrove, Aki Tsuchiyagaito, Zsofia P Cohen et al.
3 citations
Mindfulness training has been shown to promote positive mental health outcomes and related changes in neural networks such as the default mode network, which has a central node in the posterior cingulate cortex (PCC). Previous work from our group reported on the impact of a novel, neurofeedback augmented mindfulness training (NAMT) task on regulation of PCC hemodynamic activity in typically...
Cognitive, Affective, & Behavioral Neuroscience
March 15, 2022
Namik Kirlic, Zsofia P Cohen, Aki Tsuchiyagaito et al.
29 citations
Mindfulness training (MT) promotes the development of one's ability to observe and attend to internal and external experiences with objectivity and nonjudgment with evidence to improve psychological well-being. Real-time functional MRI neurofeedback (rtfMRI-nf) is a noninvasive method of modulating activity of a brain region or circuit. The posterior cingulate cortex (PCC) has been hypothesized...
Brain Sciences
March 9, 2022
Xiaoqian Yu, Zsofia P Cohen, Aki Tsuchiyagaito et al.
Mindfulness training (MT) reduces self-referential processing and promotes interoception, the perception of sensations from inside the body, by increasing one's awareness of and regulating responses to them. The posterior cingulate cortex (PCC) and the insular cortex (INS) are considered hubs for self-referential processing and interoception, respectively. Although MT has been consistently...