Zsofia P Cohen

Posterior cingulate cortex downregulation training using fMRI neurofeedback in adolescents with early life adversity exposure: a randomized, single-blind trial.

Translational Psychiatry July 13, 2025 Xiaoqian Yu, Aki Tsuchiyagaito, Masaya Misaki et al. 4 citations

Early life adversity (ELA) disrupts default mode network (DMN) integrity subserving self-referential processes involved in emotional awareness and regulation. Mindfulness training (MT) reduces self-referential processing and down-regulates the DMN. We employed neurofeedback-augmented mindfulness training (NAMT), combining a core mindfulness strategy (focusing on breath) with real-time fMRI...

DOI: 10.1038/s41398-025-03445-w (opens in new tab) Full text (opens in new tab) Meditation Awareness practice Mindfulness for adolescents Emotional regulation +11

Augmenting mindfulness training through neurofeedback: a pilot study of the pre-post changes on resting-state functional connectivity in typically developing adolescents.

Frontiers in Neuroscience 2024 Kelly T. Cosgrove, Aki Tsuchiyagaito, Zsofia P Cohen et al. 3 citations

Mindfulness training has been shown to promote positive mental health outcomes and related changes in neural networks such as the default mode network, which has a central node in the posterior cingulate cortex (PCC). Previous work from our group reported on the impact of a novel, neurofeedback augmented mindfulness training (NAMT) task on regulation of PCC hemodynamic activity in typically...

DOI: 10.3389/fnins.2024.1397234 (opens in new tab) Full text (opens in new tab) Mindfulness Adolescence FMRI Neurofeedback Functional connectivity +1

Self-regulation of the posterior cingulate cortex with real-time fMRI neurofeedback augmented mindfulness training in healthy adolescents: A nonrandomized feasibility study

Cognitive, Affective, & Behavioral Neuroscience March 15, 2022 Namik Kirlic, Zsofia P Cohen, Aki Tsuchiyagaito et al. 29 citations

Mindfulness training (MT) promotes the development of one's ability to observe and attend to internal and external experiences with objectivity and nonjudgment with evidence to improve psychological well-being. Real-time functional MRI neurofeedback (rtfMRI-nf) is a noninvasive method of modulating activity of a brain region or circuit. The posterior cingulate cortex (PCC) has been hypothesized...

DOI: 10.3758/s13415-022-00991-4 (opens in new tab) Full text (opens in new tab) Mindfulness Neurofeedback Posterior cingulate Anterior cingulate cortex +8

Neurofeedback-Augmented Mindfulness Training Elicits Distinct Responses in the Subregions of the Insular Cortex in Healthy Adolescents.

Brain Sciences March 9, 2022 Xiaoqian Yu, Zsofia P Cohen, Aki Tsuchiyagaito et al.

Mindfulness training (MT) reduces self-referential processing and promotes interoception, the perception of sensations from inside the body, by increasing one's awareness of and regulating responses to them. The posterior cingulate cortex (PCC) and the insular cortex (INS) are considered hubs for self-referential processing and interoception, respectively. Although MT has been consistently...

DOI: 10.3390/brainsci12030363 (opens in new tab) Full text (opens in new tab) Mindfulness Awareness Adolescents Insula +2

The effect of a mindfulness-based stress intervention on neurobiological and symptom measures in adolescents with early life stress: a randomized feasibility study

BMC Complementary Medicine and Therapies April 15, 2021 Zsofia P Cohen, Kelly T. Cosgrove, Elisabeth Akeman et al. 38 citations

BACKGROUND: Early life stress (ELS) has been linked to poor mental and physical health outcomes in adolescence and adulthood. Mindfulness reduces symptoms of depression and anxiety and improves cognitive and social outcomes in both youth and adults. However, little is known whether mindfulness can mitigate against the adverse neurobiological and psychological effects of ELS. This study aimed to...

DOI: 10.1186/s12906-021-03295-1 (opens in new tab)