Mindfulness-based interventions are known to enhance emotion regulation and stress management, yet their neural mechanisms remain incompletely understood. Effective coping strategies for emotion regulation and stress management would be particularly beneficial for healthcare students, frequently exposed to highly stressful situations. Based on prior work implicating hippocampal-somatomotor...
Psycho-OncologyNovember 1, 2025Marie-Estelle Gaignard, Dominica Martin, Jelena Stanic et al.
Mindfulness-Based Interventions (MBIs) are recognized as beneficial in oncology supportive care. While qualitative analyses of mindfulness program experiences exist, this is the first mixed methods study to examine patients' experiences after participating in the online Mindfulness-Based Cancer Recovery (e-MBCR) program. The SERENITY study was a pilot randomized controlled trial evaluating the...
Chronic pain requires an integrative approach. The prescription of opioids is increasing in Europe, including Switzerland, for the -treatment of chronic pain, despite their modest effectiveness. Mindfulness-based interventions have demonstrated their effectiveness in the management of chronic pain. The MORE program (Mindfulness-Oriented Recovery Enhancement) is an integrative therapy that uses...
This study aimed to evaluate the effectiveness of a short mindfulness intervention on anxiety, stress and depression symptoms, as well as on inhibition of dominant responses and academic performance among university students. Fifty volunteers (M(age) = 23.8; SD = 5.3) with high levels of depression, anxiety or stress were randomly allocated to a mindfulness practice group or an active control...
Previous research links contemplative practices, such as meditation, with stress reduction. However, little is known about the psychological mechanisms underlying this relationship. This study compares the physiological stress response (reactivity and recovery) measured by changes in salivary cortisol, heart rate, heart rate variability, and the associated stress-related ratings in long-term...
Obsessive-compulsive disorder (OCD) is a frequent and severe disease, potentially inducing a major impairment for the patient and burden for their family. Recent research in psychiatry and neuroscience have led to better comprehension of the disease's mechanisms and helped to improve its treatment. However, a large proportion of patients have refractory symptoms, including for traditional...
This study focused on patients with bipolar disorder (BD), several years after their participation in mindfulness-based cognitive therapy (MBCT). It aimed at documenting sustained mindfulness practice, perceived long-term benefit from the program, and changes regarded as direct consequences of the intervention. This cross-sectional survey took place at least 2 years after MBCT for 70.4% of...
IMPORTANCE: Relapse prevention in recurrent depression is a significant public health problem, and antidepressants are the current first-line treatment approach. Identifying an equally efficacious nonpharmacological intervention would be an important development. OBJECTIVE: To conduct a meta-analysis on individual patient data to examine the efficacy of mindfulness-based cognitive therapy...
Few studies have examined changes of diurnal cortisol profiles prospectively, in relation to non-pharmacological interventions such as mindfulness-based cognitive therapy (MBCT). Fifty-six patients remitted from recurrent depression (≥3 episodes) were included in an 8-week randomized controlled trial comparing MBCT plus treatment as usual (TAU) with TAU for depression relapse prophylaxis....
RésuméLes approches basées sur la méditation de pleine conscience (mindfulness) connaissent un développement considérable dans le champ des psychothérapies, depuis la création par Jon Kabat-Zinn d’un programme pour la réduction du stress (MBSR) dans les années 1970.Dans cet article, nous décrivons les principales applications thérapeutiques de ces approches et les processus pouvant expliquer...
The present open study investigates the feasibility of Mindfulness-based cognitive therapy (MBCT) in groups solely composed of bipolar patients of various subtypes. MBCT has been mostly evaluated with remitted unipolar depressed patients and little is known about this treatment in bipolar disorder. Bipolar outpatients (type I, II and NOS) were included and evaluated for depressive and hypomanic...
Mindfulness is the fundamental attentional stance underlying all streams of Buddhist meditative practice. It has been described as "paying attention in a particular way: on purpose, in the present moment, and nonjudgmentally." During the last years, mindfulness practice has been evaluated and introduced into several mental health treatments (Mindfulness Based Stress Reduction; Dialectical...