European Journal of Trauma & Dissociation
June 30, 2023
Alyssia Simos, David C. Berle
10 citations
Nightmares are a re-experiencing symptom of Post-Traumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). They are intrusive, involuntary and have a significant impact on wellbeing, suggesting they have substantial clinical relevance. However, little is known about the phenomenological features of post-traumatic nightmares and how they impact the severity of PTSD and CPTSD symptoms....
Journal of Community Safety and Well-Being
June 30, 2023
Renae M. Stevenson
The body of research demonstrating the psychological and physiological benefits of mindfulness-based interventions (MBIs) is robust and spans decades, yet its adaptation for a population at significantly higher-than-average risk of negative health outcomes, operational stress injuries, moral injury, and burnout is in its infancy. Failing to address these risks has costs not just for the...
Psihologija
June 9, 2023
Protić Sonja, Gorzka Robert-Jacek, Höllmer Helge et al.
Gender is one of the well-recognized risk factors for idiopathic nightmares, but rarely connected to posttraumatic nightmare characteristics. Thus, this study aims to test gender differences in (posttraumatic) nightmare characteristics after controlling for trauma-related psychopathology in a large sample of people who experienced trauma. Research participants were 707 soldiers (mean age 31.3...
Neuropsychopharmacology
June 3, 2023
Or Duek, Nachshon Korem, Yutong Li et al.
71 citations
NMDA receptor antagonists have a vital role in extinction, learning, and reconsolidation processes. During the reconsolidation window, memories are activated into a labile state and can be reconsolidated in an altered form. This concept might have significant clinical implications in treating PTSD. In this pilot study we tested the potential of a single infusion of ketamine, followed by brief...
Sleep
May 29, 2023
Regan Christian, Danica C. Slavish
Abstract: Introduction: Most adults experience a traumatic event at some point in their lifetime, and some also go on to develop posttraumatic stress disorder (PTSD). Sleep disorders such as insomnia and nightmares are common in PTSD, which may be due to hyperarousal and distressing memories that disrupt the sleep-wake cycle. Complex PTSD (C-PTSD) is a new distinct diagnosis of PTSD that...
BMC Psychiatry
May 5, 2023
Stefan Roepke, Nikola Schoofs, Kathlen Priebe et al.
Distressing nightmares are a core symptom of posttraumatic stress disorder (PTSD) and contribute to psychiatric comorbidity, impaired physical health and decreased social functioning. No specific pharmacological treatment for PTSD-related nightmares is yet approved. Preliminary clinical data indicate that cannabinoid agonists can improve nightmares and overall PTSD symptoms in patients with...
Sleep
May 1, 2023
Elena Stuewe, Katherine B. Malcolm, Steven H. Woodward et al.
Abstract Introduction Observational research demonstrates a strong association between nightmares, insomnia, and sleep apnea in veterans with posttraumatic stress disorder (PTSD), supportive of the notion of a “complex sleep disturbance”. Relations between sleep disturbances and PTSD are often bi-directional and disturbed sleep affects non-sleep PTSD outcomes. We aimed to examine relationships...
Journal of the American Association of Nurse Practitioners
May 1, 2023
Amy L Haycraft
The development of anxiety disorders and post-traumatic stress disorder (PTSD) is complex. Both delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are of potential therapeutic use. Evidence suggests that cannabis has a beneficial effect on neural circuitry involved in fear regulation. In the United States, cannabis is considered either medical or recreational and can contain pure THC or...
The Journal for Nurse Practitioners
May 1, 2023
Amy L Haycraft
Posttraumatic stress disorder (PTSD) treatment options, including the potential use of psychedelic-assisted therapy, are reviewed. Traditional PTSD treatment remains ineffective for many, and includes, trauma focused cognitive behavioral therapy, eye movement desensitization and remodeling, and selective serotonin reuptake inhibitors. Evidence has shown that with further supportive research,...
Heliyon
May 1, 2023
Jolien K E Veraart, M. van Westenbrugge, J.E. van Wulfften Palthe et al.
30 citations
Introduction: Ketamine and its S-enantiomer esketamine are novel pharmacotherapeutic options for treatment resistant depression (TRD). There is growing evidence on the efficacy for other psychiatric disorders, including posttraumatic stress disorder (PTSD). It is hypothesized that psychotherapy may further potentiate the effects of (es)ketamine in psychiatric disorders. Methods: Repeated oral...
Sleep
May 1, 2023
Afik Faerman, Lauren Anker, Kirsten Cherian et al.
5 citations
Abstract Introduction Ibogaine is an indole alkaloid traditionally used in spiritual and healing rites in some African cultures. Ibogaine is primarily studied in the context of substance dependence, but indications suggest it may enhance recovery from trauma. Here, we investigated the effects of ibogaine treatment for multisystem effects of exposure to repeated blasts and combat on...
BMJ Open
May 1, 2023
Alan K. Davis, Adam W. Levin, Paul Nagib et al.
19 citations
Introduction Psilocybin-assisted therapy has shown significant promise in treating the cluster of mood and anxiety symptoms that comprise post-traumatic stress disorder (PTSD) but has yet to be tested specifically in this condition. Furthermore, current pharmacological and psychotherapeutic treatments for PTSD are difficult to tolerate and limited in efficacy, especially in the US Military...
Journal of Child & Adolescent Trauma
April 21, 2023
L. Fortuna, William Martinez, Michelle V. Porche
Purpose: Unaccompanied immigrant children (UIC) experience significant mental health concerns, particularly posttraumatic stress. This is a vulnerable population, yet little systematic research has examined the effectiveness of evidence-based models such as cognitive behavioral therapy (CBT) to meet their needs. Integrating religious beliefs and spirituality into therapy could elucidate better...
Frontiers in Psychiatry
April 14, 2023
Jennifer L. Jones
4 citations
BackgroundAlcohol and other substance use disorders are commonly associated with post-traumatic stress disorder (PTSD), and the presence of these comorbidities is associated with worse treatment outcomes. Additionally, disparities in substance and PTSD prevalence have been associated with minority races and ethnicities, and minorities have been shown to be less likely to engage in treatment....
Contemporary Clinical Trials
April 12, 2023
Jordan P Davis, Eric R Pedersen, Brian Borsari et al.
Background: Post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) are highly prevalent, and co-occurring among post-9/11 veterans. Mobile health (mHealth) applications, specifically those focused on mindfulness-based techniques, may be an effective avenue to intervene with veterans who cannot or will not seek care at traditional in-person settings. Thus, to address areas of...
Journal of Psychopathology and Clinical Science
April 6, 2023
E. Wolf, Sage E. Hawn, Danielle R. Sullivan et al.
Approximately 10–30% of individuals with posttraumatic stress disorder (PTSD) exhibit a dissociative subtype of the condition defined by symptoms of depersonalization and derealization. This study examined the psychometric evidence for the dissociative subtype of PTSD in a sample of young, primarily male post-9/11-era Veterans (n = 374 at baseline and n = 163 at follow-up) and evaluated its...
April 5, 2023
Vladimir Adrien, Marion Trousselard, Félix Schoeller
17 citations
preprint
The concept of agency, or an individual's sense of control over their actions and external events, is important in the context of peritraumatic dissociation, and its cardinal importance in post-traumatic stress disorder (PTSD). This article provides a roadmap for the development of agency-based therapies in the future, along with offering an "enactive" perspective on trauma. We discuss the...
Cannabis and Cannabinoid Research
April 2023
Nicole A Lookfong, Wesley M Raup-Konsavage, Yuval Silberman
Background: The endocannabinoid (eCB) system plays an important role in homeostatic regulation of anxiety and stress responses; however, the eCB system can be disrupted following traumatic stressors. Additionally, traumatic or chronic stressors that occur during adulthood or early life can cause long-lasting disturbances in the eCB system. These alterations interfere with...
Mindfulness
April 1, 2023
Stella Kümmerle, Thomas Heidenreich, Meike Müller-Engelmann
Abstract Objectives Despite various methodological concerns, previous studies mainly use questionnaires to assess mindfulness. Following a multi-measurement approach, the present study aimed to evaluate the added value of an experience-sampling measure in the context of posttraumatic stress disorder (PTSD) and depression. Method Data were collected in a PTSD group, depression group, and control...
Australian & New Zealand Journal of Psychiatry
April 1, 2023
Gillinder Bedi, Susan M Cotton, Alexandre A. Guerin et al.
17 citations
Recent years have seen escalating media, public and scientific interest in psychedelic medicine. Australia and New Zealand have been late to this research; however, in the past 2 years, rapid developments suggest that this is changing. Here, we argue for the need to critically review existing evidence in this field to guide future directions. We focus on...