Von Ethnopharmakologie zur klinischen Psychedelika-Therapie — Christian Rätsch, Stanislav Grof und der Übergang zur evidenzbasierten Forschung billingual
Emotional acceptance is an important practice for recognizing anxiety, anger, appetite, the need for approval, jealousy, loneliness, procrastinatory impulses, and other internal reactions as observable experiences rather than denying or suppressing them. However, even after emotions and desires have been accepted, they may become sources of personality-level self-blame when they are identified...
BackgroundPsychiatry has long maintained an ambivalent relationship with religion and spirituality, often acknowledging their relevance while remaining cautious about clinical engagement.ObjectivesThis article examines the historical, conceptual, and clinical tensions surrounding spirituality in psychiatry and explores how contemporary psychedelic research has renewed attention to meaning and...
Background: ±3,4-methylenedioxymethamphetamine (MDMA) has positive effects on socio-emotional processing and MDMA-Assisted Therapy (MDMA-AT) showed promise for treating SAD in a previous placebo-controlled trial. Aims: Develop a preliminary estimate of clinical response and safety for MDMA-AT versus waitlist in adults with SAD. Secondary aims included refinement of a standardized psychotherapy...
3,4-Methylenedioxymethamphetamine (MDMA)-assisted psychotherapy (MDMA-AT) is being investigated as a treatment for several psychiatric disorders, particularly posttraumatic stress disorder. Phase 2 and 3 trials typically administered a first dose of MDMA followed by a second "booster" dose 1.5-2.5 h later, to extend the acute effect duration. However, the risks and benefits of the booster dose...
Ketamine-assisted psychotherapy (KAP) is moving from the periphery toward the mainstream of mental healthcare. Research on the use of KAP in the context of couple therapy, however, remains limited. This phenomenological analysis sought data from psychotherapists ( n = 9), representing four different modalities of couple therapy, who are incorporating ketamine into their work with dyads....
Chronic pain is common, costly, and for many, remains inadequately treated by existing pharmacologic and non-pharmacologic approaches. In parallel with growing dissatisfaction with conventional therapies, classic serotonergic psychedelics, such as psilocybin, lysergic acid diethylamide (LSD), ayahuasca, N,N-dimethyltryptamine (DMT), and mescaline, administered alone or within...
Psychedelic-assisted therapy and integration are gaining renewed recognition as an effective mental health intervention. However, occupational therapy (OT) is largely missing from psychedelic integration practices despite clear overlap integration objectives. This project involved a comprehensive review of the literature, along with practitioner interviews and a survey to examine current...
Most academic psychedelic research is clinically oriented, with industry research primarily focusing on the medicalization of these substances. Given the rapid policy changes and the surge in interest among researchers and the public, it is imperative to assess and document the research priorities of the broader psychedelic community. This study aimed to identify these priorities through an...
Abstract Background Prolonged grief disorder (PGD) is a clinically distinguishable bereavement-related condition characterized by persistent yearning, identity disruption, and impaired functioning, formalized in DSM-5-TR and ICD-11 (6L72) and empirically distinguishable from but frequently co-occurring with major depressive disorder. Approximately 7 to 10 percent of bereaved adults meet...