Jamur telah digunakan sejak lama sebagai bahan pangan karena berbagai kandungan nutrisi dan manfaat yang baik untuk kesehatan. Di Indonesia, sebagian besar masyarakat lokal telah terbiasa merambah jamur liar edible untuk dikonsumsi. Salah satu jamur liar konsumsi yang sering dicari oleh masyarakat adalah Termitomyces . Namun jamur ini seringkali sulit dibedakan dengan Inocybe karena sruktur...
Psilocybin-containing mushrooms, commonly known as magic mushrooms, have been used since ancient and recent times for depression and to improve quality of life. However, their anti-inflammatory properties are not known. The study aims at investing cytotoxicity; antioxidant; and, for the first time, anti-inflammatory effects of Psilocybe natalensis, a psilocybin-containing mushroom that grows in...
This review demonstrates how qualitative research of psychedelic treatments can contribute to distinguishing specific features of specific substances, and carry otherwise undiscovered implications for the treatment of specific psychiatric disorders.
August 7, 2020Olga V. Mitina, М.а. Винникова, А. Н. Решетилов et al.
preprint
## AimInvestigate accounts from breath-holding freedivers about high efficiency in coping with adversity and pain, immediately quitting addictions, attaining harmonious meaningful life, becoming perspicacious and compassionate, getting spontaneous religious experience. ## Findings Full Mystical Experience is confirmed to happen in freediving, i.e. it is the same Mystical experience found in...
Psychedelics are newly respectable. Evidence suggests that a variety of ills, from anxiety and depression to addictions and post-traumatic stress disorder, respond to them in a way hitherto unseen within psychiatry. The researchers involved have been careful to clean up the reputation of a class of drugs that, despite a wealth of promising evidence for their therapeutic effects in the 1960s and...
The putative active metabolite of aeruginascin, a naturally occurring tryptamine of "magic mushrooms," has been synthesized and structurally characterized. Competitive radioligand binding assays demonstrate that it has a high affinity at human serotonin receptors 5-HT1A, 5-HT2A, and 5-HT2B, though it does not bind at the 5-HT3 receptor, where activity was previously predicted.
Abstract Since 2006, there has been a resurgent interest in the pharmacology and therapeutics of psychedelic drugs. Psilocybin, the 4‐phosphoryl ester of N,N ‐dimethyltryptamine (DMT), has been studied most often, but DMT itself is also appealing because of its brief but profound psychological effects and its presence as an endogenous substance in mammalian brain. Although there have been a few...
Abstract This article addresses the complex role of mushrooms, particularly that of the fly agaric ( Amanita muscaria ) [Russian: Mukhomor ], in the art of Moscow conceptualism in a broad setting. This paper explores the mythopoetic theme of mushroom-induced beliefs, which influenced the Moscow conceptualists, and employs background historical scholarship by R.G. Wasson, V.N. Toporov, T.J....
Drug-plasma protein interaction is a critical concern in monitoring drug circulation and drug-drug interactions. The present study aimed to investigate the interaction of psychedelic drugs such as lysergic acid diethylamide (LSD), dimethyltryptamine (DMT), 2,5-dimethoxy-4-iodoamphetamine (DOI), psilocybin, psilocin, and mescaline with human serum albumin (HSA). The 3D structures of LSD, DMT,...
Los hongos psilocibios han sido consumidos en prácticamente todo el mundo por diversos grupos humanos en los albores de sus culturas, en tiempos que se retrotraen en un pasado distante. Al parecer evolucionaron como un arma química para defenderse de los insectos y demás depredadores, sin embargo la psilocina es inocua en términos toxicológicos para nosotros, lo que realmente estaría induciendo...