Research Square (Research Square)
July 18, 2023
Sanah Malomile Nkadimeng, L. Hay, Christiaan Ml Steinmann et al.
1 citation
Abstract Background Psilocybin-containing mushrooms induce antidepressant and momentary increase in blood pressure (BP) with potential risk to users with cardiovascular diseases. Irregularities in nitric oxide (NO) levels play a key role in endothelial dysfunctions leading to increases in BP. Mushrooms species show large variation in potency which may potentially induce different outcomes and...
Preprints.org
June 6, 2023
Sanah Malomile Nkadimeng, Christiaan M.l. Steinmann, J.n. Eloff
1 citation
preprint
Psilocybin-containing mushrooms, commonly known as magic mushrooms have antidepressant effect, however, their safety in cardiovascular diseases such as heart failure is not fully known and needs to be investigated. Cardiac hypertrophy is an independent risk factor for heart failure morbidity and mortality. Angiotensin II (Ang-II) plays a major role in the pathogenesis of cardiac hypertrophy. We...
Journal of Inflammation Research
August 1, 2021
Sanah Malomile Nkadimeng, Christiaan Ml Steinmann, J.n. Eloff
77 citations
The study suggested that the hot-water extracts of the four psilocybin-containing magic mushrooms have potential anti-inflammatory effects executed by down-regulating pro-inflammatory mediators.
Scientific Reports
December 18, 2020
Sanah Malomile Nkadimeng, Christiaan M.l. Steinmann, J.n. Eloff
31 citations
Abstract Prevalence of major depression in people with chronic heart failure is higher than in normal populations. Depression in heart failure has become a major issue. Psilocybin-containing mushrooms commonly known as magic mushrooms, have been used since ancient times for their mind healing properties. Their safety in cardiovascular disease conditions is not fully known and may pose as a risk...
Plants
August 31, 2020
Sanah Malomile Nkadimeng, Alice Nabatanzi, Christiaan M.l. Steinmann et al.
66 citations
Psilocybin-containing mushrooms, commonly known as magic mushrooms, have been used since ancient and recent times for depression and to improve quality of life. However, their anti-inflammatory properties are not known. The study aims at investing cytotoxicity; antioxidant; and, for the first time, anti-inflammatory effects of Psilocybe natalensis, a psilocybin-containing mushroom that grows in...