TramesOctober 30, 2025Swati Samantaray, Sahadeb Patro
Religion was our first attempt at literature, cosmology, ecology, making sense of where we are in the universe. All religions are inherently predisposed to mystical experience â a harmonious and balanced existence and substantiation of Nature and man â man, who is conscious of his existence both in the material and the spiritual realm, as man is the highest spirit and the lowest matter...
AbstractThis study examines al-Ghazālī's method of metaphysical doubt in light of phenomenological approaches, particularly that of Edmund Husserl. It argues that al-Ghazālī's intellectual crisis and subsequent journey toward certain knowledge reveal a proto-phenomenological attitude, wherein doubt is not an end in itself but a methodological suspension aimed at uncovering indubitable truths....
Understanding the biophysical basis of consciousness remains a substantial challenge for 21st-century science. This endeavor is becoming even more pressing in light of accelerating progress in artificial intelligence and other technologies. In this article, we provide an overview of recent developments in the scientific study of consciousness and consider possible futures for the field. We...
The current research design is rooted in an qualitative framework, aimed to understand how individuals make sense of anonymous or extraordinary experiences that surpass orthodox psychological explanations. The semi structured interviews were conducted with 11 adult participants, six male, and five females, aged ranges 18-50 years. These participants were selected through the purposive sampling...
AIMS: Autoscopic phenomena (AP) are distinct manifestations of epileptic seizure semiology and are also identified in diverse psychiatric disorders. Our study aimed to map the brain AP network and characterize its multimodal signatures. METHODS: By performing lesion network mapping using the human connectome dataset (n = 1000), we investigated the brain AP network derived from 25 cases of AP...
Knowledge, understanding, and attention to its levels, as well as recognition of the obstacles of each level are part of the fundamental principles in the mystical system presented in Mathnawi Manawi and the ancient Upanishads. The emphasis in these two mystical systems is prominent in achieving transcendental and intuitive knowledge in order to show more depth of truth to its followers....
Sleep onset is characterized by a departure from arousal, and can be separated into well-differentiated stages: NREM (which encompasses three substages: N1, N2 and N3) and REM (Rapid Eye Movement). Awake brain dynamics are maintained by various wake-promoting mechanisms, particularly the neuromodulators Acetylcholine (ACh) and Noradrenaline (NA), whose levels naturally decrease during the...
Background: Psychedelic-assisted therapies show promise for MDD, PTSD, and addiction, yet mechanisms are often framed as 5-HT2A-centric, despite evidence of GABAergic pathology in these conditions.Hypothesis (Author Perspective): As a chemist examining psychedelic pharmacology, I propose that inhibitory-circuit modulation acts as a necessary systems-level gate converting transient 5-HT2A...
Inner-body sensations (interoceptive sensations) have only recently become a full object of philosophy. This is due to the fact that the naturalistic theory of phenomenal consciousness is expanding by new empirical data and requiring philosophical analysis. Also, the traditional object of cognitive sciences is being transformed into a multidimensional philosophical category. At the same time,...
Background/Objectives: Patients in palliative care often experience multifaceted forms of suffering that extend beyond physical symptoms, including existential distress, loss of meaning, and emotional pain. Ketamine-assisted psychotherapy (KAP) has emerged as a promising intervention for alleviating such complex forms of suffering, yet models specifically tailored to palliative populations...