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Neuroplasticity: all studies

Page 58 of 178: studies 571 to 580 of 1,772, newest first. Back to the neuroplasticity overview

Research

PSYCHIATRY The Case for Starting Over

September 30, 2026 Abraham Peled preprint

AbstractPsychiatry is the only branch of medicine that still diagnoses without reference to the organ it treats. Psychiatry: The Case for Starting Over argues that this is a structural failure rather than a temporary gap. The descriptive nosology inherited from Kraepelin and formalized in the DSM achieved diagnostic reliability at the cost of validity. Its categories were assembled by committee...

THE IMPACT OF SELECTED PSYCHOACTIVE SUBSTANCES - COCAINE, AMPHETAMINE, PSILOCYBIN, MDMA, AND KETAMINE - ON THE BODY IN PHYSICAL AND PSYCHOLOGICAL ASPECTS AND THEIR MAIN MECHANISMS OF ACTION: A NARRATIVE REVIEW

International Journal of Innovative Technologies in Social Science September 28, 2026 Klaudia Karolina Wójcik, Michal Kieres, Krzysztof Sebastian Habirek et al.

The article aims to compare receptor mechanisms related to neurotransmitters for some of the most widely used psychoactive substances - amphetamine, cocaine, ecstasy (MDMA), and psilocybin - and to link these mechanisms to cardiovascular effects, thermoregulation, and neurotoxicity. The review is based mainly on in vitro studies on transporters and receptors, animal models, and controlled...

Multimodal predictors of response to intravenous ketamine in treatment-resistant depression: toward personalized treatment in major depressive and bipolar disorders.

CNS Spectrums September 28, 2026 Magda Malewska-Kasprzak, Filip Rybakowski, Monika Dmitrzak-Weglarz

Intravenous ketamine is a rapid-acting intervention for treatment-resistant depression (TRD) in adults with major depressive disorder and bipolar disorder (BD). While efficacy is established, a comprehensive integration of clinical, neurophysiological, biomarker, metabolic, and cognitive predictors remains lacking, limiting precision CNS-targeted therapy. To synthesize recent evidence on...

The Phase-Shift Hypothesis: The Influence of Homeostasis Within Neural Networks During Sleep and the Emergence of Dream Phenomenology

Zenodo (CERN European Organization for Nuclear Research) September 26, 2026 Douwe Fennema preprint

Abstract During wakefulness, experience continually changes the functional organization of neural networks. Repetition, attention, emotional significance, and other forms of experience-dependent activation can affect the relative strength of synaptic relationships (Hebb, 1949; Bliss & Lømo, 1973; Dudek & Bear, 1992). During sleep, direct coupling to external sensory input and behavioral output...

L'Analogic Meditation nel contesto della Sclerosi Laterale Amiotrofica (SLA): razionale psiconeurosomatico, evidenze preliminari e proposta di un programma di ricerca

Zenodo (CERN European Organization for Nuclear Research) September 26, 2026 Alessandro Mahony preprint

L'Analogic Meditation (AM) è una pratica meditativa strutturata che integra visualizzazione simbolica, suggestione ideoplastica e lavoro sul corpo-mente, sviluppata da Alessandro Mahony nell'ambito di un approccio psiconeurosomatico integrato. A oggi, l'AM non è stata oggetto di studi clinici nella Sclerosi Laterale Amiotrofica (SLA). Tuttavia, sulla base delle conoscenze neurobiologiche...

Analogic Meditation in the Context of Amyotrophic Lateral Sclerosis (ALS): Psychoneurosomatic Rationale, Preliminary Evidence, and Proposal for a Research Program

Zenodo (CERN European Organization for Nuclear Research) September 26, 2026 Alessandro Mahony preprint

Analogic Meditation (AM) is a structured meditative practice that integrates symbolic visualization,ideoplastic suggestion, and body-mind work, developed by Alessandro Mahony withinan integrated psychoneurosomatic approach. To date, AM has not been the subject of clinicalstudies in Amyotrophic Lateral Sclerosis (ALS). However, based on current neurobiologicalknowledge on meditation, hypnosis,...

The Effects of Mindfulness-Based Interventions on Proprioception: A Bayesian Multilevel Meta-Analysis of Evidence from Randomized Controlled Trials

Mindfulness September 25, 2026 Senyao Du, Guowen Ai, Shiao Zhao et al.

Proprioception is crucial for physical activities, motor control, balance, and coordination, yet strategies to enhance it remain debated. Mindfulness-based interventions (MBIs) may improve proprioception by enhancing body awareness through attention regulation and body-mind synergy. MBIs offer low intensity, low cost, and good repeatability. This study hypothesized that MBIs improve...

Ketamine for Treatment-Resistant Depression in Adolescents: Hope or Risk?

Journal of Education, Health and Sport September 24, 2026 Anna Kamosińska, Julia Pająk, Olga Sławatyniec et al.

Treatment-resistant depression (TRD) in adolescents remains a major clinical challenge because of the limited efficacy of conventional antidepressants and the high risk of suicidal behavior. Ketamine has emerged as a rapidly acting antidepressant with a unique glutamatergic mechanism, promoting neuroplasticity and reducing neuroinflammation. Clinical studies demonstrate significant symptom...

Enhancing attention network and neural efficiency through brief mindfulness meditation

npj Science of Learning September 23, 2026 Yong Huang, Jia-Hui Guo, Shuai Zheng et al.

Abstract The effects of brief mindfulness meditation (BMM) on attention networks remain unclear. Using Event-Related Potentials (ERPs), this study investigated how 18 days of Anapanasati meditation (JW2016 mental exercises, 15 min/day) modulates attentional functions in healthy adults. Behaviorally, BMM produced a selective enhancement of the executive control network, evidenced by...

Peripheral Biomarkers of Response to Ketamine and Esketamine Treatment in Unipolar Depressive Disorder—A Scoping Review

Journal of Personalized Medicine September 23, 2026 Aleksandra Metelska, Wojciech Ziemichód, Hanna Karakuła-juchnowicz

Objectives: A significant problem in the treatment of depressive disorders is the growing number of cases of so-called treatment-resistant depression (TRD). There is evidence of ketamine’s effectiveness in treating TRD, with response rates ranging from 40% to 90%. This review aimed to map available studies on peripheral biomarkers of response to ketamine and esketamine in the treatment of...