La mescaline, de même que d'autres drogues, change la voie de la perception visuelle en déplaçant la « lecture » de la figure vers le fond et en rendant les graphes linéaires. Ces modifications bouleversent la construction de l'illusion de réalité. L'auteur étudie ces métamorphoses de la perception visuelle, stimulées par les modificateurs de conscience, telles qu'elles apparaissent dans...
Je vais enfin savoir si Gallimard ou quelqu’un d’autre va promettre de publier "Un voyage en Grande Garabagne". Il est fini, je n’y ajoute plus rien (il ne me reste plus qu’à taper à la machine). Il m’exaspère à tel point que si je retournais à Paris en ce moment, ce serait pour assassiner deux ou trois personnes à son propos.Henri Michaux, lettre à Jean Paulhan, Anvers Janvier 1935. De...
The effects of 4-bromo-2,5-dimethoxyphenethylamine (Nexus), 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxyphenyl-2-butanamine (BDB), and cathinone were studied in the newly hatched chicken and compared to the effects of d-amphetamine and three hallucinogens in the same species. Cathinone, a psychomotor stimulant in man (6), produced effects that were qualitatively similar to effects...
SOME EFFECTS OF GROUP DRUG TAKING ERWIN DI CYAN* The purpose of this paper is to discuss briefly some aspects of the differences between drug effects when drugs are used in groups as distinguished from their solitary use. The human organism responds to a variety of stimuli. Its response to signals may be physiological or psychological. The latter response includes recollections by (a) retrieval...
Henri Michaux first discovered mescaline in 1956. This encounter proved a lasting influence on the work of the writer who, for at least ten years, struggled to circumscribe, then tried to explain the nature of the terrible shock he had received from the mind-altering chemical. The event was so important for the poet that in due time, it brought about a veritable conversion, a total and...
... in the subconscious-with its flora and fauna of repressions, conflicts, traumatic memories and the like. Travelling further, we reach a kind of far West, inhabited by Jungian archetypes and the raw materials of human mythology. Beyond this region lies a broad Pacific. Wafted across it on the wings of mescaline ... we reach what might be called the Antipodes of the mind. -Aldous Huxley, The...
Under mescaline it happens that approaching objects appear to grow smaller. A limb or other part of the body, the hand, mouth or tongue seems enormous, and the rest of the body is felt as a mere appendage to it. The walls of the room are 150 yards apart, and beyond the walls is merely an empty vastness [. ] Sometimes motion is no longer seen, and people seem to be transported magically from one...
Several reports have speculated that the tryptamine-derived drug alpha-ethyltryptamine (AET) may have effects similar to those of the amphetamine-derived drug 3,4-methylenedioxymethamphetamine (MDMA). Indeed, the US Drug Enforcement Administration has recently placed AET on the Schedule I list because of its putative similarity to MDMA. The Behavioral Pattern Monitor, which quantifies locomotor...
The isomers of 3,4-methylenedioxyamphetamine (MDA) functioned as discriminative stimuli in rats trained to discriminate either (-) MDA (1.25mg/kg) or (+) MDA (1.25mg/kg) from saline. Dose- and time-response curves indicated that drug lever selection occurred at doses of at least 1.00mg/kg of (-) MDA and 0.75mg/kg of (+) MDA and that drug-appropriate responding for both isomers was maintained...
THE RISE, DECLINE, AND FALL OF LSD ROBERT F. ULRICH and BERNARD M. PATTEN* The urge to transcend self-conscious selfhood is ... a principal appetite of the soul. When, for whatever reason, men and women fail to transcend themselves by means of worship, good worh and spiritual exercises, they are apt to resort to religion's chemical surrogates.—Aldous Huxley. [1] On April 16, 1943, a fascinating...