Jack DeRuiter - The Consciousness Library

GC–MS and GC–IR analysis of methylenedioxyphenylalkylamine analogues of the psychoactive 25X-NBOMe drugs

May 1, 2021 Younis Abiedalla, Ahmad J. Almalki, Jack DeRuiter et al.

Abstract Twelve secondary amines representing structural analogues of the classic NBOMe category of novel psychoactive substances were prepared and evaluated in GC-EI-MS and vapor phase GC–IR studies. These compounds all contain the methylenedioxy group fused with the aromatic ring of the phenethyl moiety in the classic NBOMe chemical framework. One subseries of analogues, the three...

DOI: 10.1016/j.forc.2021.100314

GC–MS analysis of N-(bromodimethoxybenzyl)-2-, 3-, and 4-methoxyphenethylamines: Inverse analogues of the psychoactive 25B-NBOMe drug

September 23, 2020 Ahmad J. Almalki, C. Clark, Younis Abiedalla et al.

Abstract The substituted phenethylamine analogues in this study are derivatives of N-(2-methoxybenzyl)-4-bromo-2,5-dimethoxyphenethylamine (25B-NBOMe) having the reverse substitution pattern for the two aromatic rings. These compounds contain only a single methoxy substituent in the phenethylamine part, and a bromodimethoxy substitution pattern in the benzyl portion. The regioisomers were...

DOI: 10.1016/j.forc.2020.100277

Structure fragmentation studies of ring-substituted N-trifluoroacetyl-N-benzylphenethylamines related to the NBOMe drugs.

Rapid communications in mass spectrometry : RCM February 28, 2020 Ahmad J. Almalki, C Randall Clark, Jack DeRuiter

The halogenated derivatives of N-(2-methoxy)benzyl-2,5-dimethoxyphenethylamine (25-NBOMe) such as the 4-bromo analogue (25B-NBOMe) represent a new class of hallucinogenic or psychedelic drugs. The purpose of this study was to determine the role of the electron-donating groups (halogen and dimethoxy) in the pathway of decomposition for the distonic molecular radical cation in the electron...

DOI: 10.1002/rcm.8593 Full text

Vapor phase GC-IR identification of regioisomeric N-methoxybenzyl-4-substituted-2,5-dimethoxyphenethylamines (NBOMe)

December 1, 2019 Ahmad J. Almalki, L. Smith, C. Clark et al.

Abstract The common NBOMe drugs of abuse, N-(2-methoxybenzyl)-4-iodo-2,5-dimethoxyphenethylamine (25I-NBOMe) and N-(2-methoxybenzyl)-4-bromo-2,5-dimethoxyphenethylamine (25B-NBOMe), can be differentiated from their corresponding 3- and 4-methoxybenzyl isomers by gas chromatography with vapor phase infrared spectroscopy. The mass spectra for these regioisomeric compounds are essentially...

DOI: 10.1016/j.forc.2019.100181

GC-MS studies on side chain regioisomers related to substituted methylenedioxyphenethylamines: MDEA, MDMMA, and MBDB.

Journal of Chromatographic Science October 1, 2010 Tamer Awad, Tarek Belal, Hadir M Maher et al.

Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equal mass have been reported as drugs of abuse in forensic studies in recent years. These compounds are 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N,N-dimethylamphetamine (MDMMA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB). A...

DOI: 10.1093/chromsci/48.9.726 Full text

GC-MS Studies on the Regioisomeric 2,3- and 3,4-Methylenedioxyphenethylamines Related to MDEA, MDMMA, and MBDB

Journal of Chromatographic Science May 1, 2007 A. L. Thigpen, Jack DeRuiter, Charles R. Clark 9 citations

Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equal mass have been reported as drugs of abuse in forensic studies in recent years. These compounds are 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N-N-dimethylamphetamine (MDMMA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB). The...

DOI: 10.1093/chromsci/45.5.229 Full text Gas chromatography–mass spectrometry

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