Journal of the Neurological Sciences
March 15, 2022
David E Smith
In 1965, I was training in clinical toxicology in the pharmacology department of the University of California San Francisco (UCSF) and living in the Haight Ashbury. I studied various psychedelics, including LSD, mescaline, and ibogaine, in human and animal models. The psychedelics were then being used as a therapeutic drug in clinical settings and researched as a potential antipersonnel agent...
Journal of Psychopharmacology
March 1, 2022
Catherine Bird, A. H. Young
As we head into the (Northern Hemisphere) spring, the Journal publishes another set of papers which illustrate the robust health of the science of psychopharmacology. Once again, papers mostly focus on psychedelic drugs and related topics reflecting the zeitgeist (Young, 2022). de Wit et al. (2022) explore translational challenges and opportunities between clinical research and laboratory...
Journal of Psychopharmacology
March 1, 2022
Max Wolff, Lea J. Mertens, Marie Walter et al.
57 citations
Background: Many benefits and some harms associated with psychedelic use could be attributable to these drugs’ acceptance/avoidance-promoting effects and corresponding changes in psychological flexibility. Underlying psychological mechanisms are insufficiently understood. Aim: The purpose of this study was the validation of a psychological model of acceptance/avoidance-promoting psychedelic...
Scientific Reports
February 16, 2022
Grant Jones, Matthew K. Nock
44 citations
Abstract Cocaine Use Disorder (CUD) is a significant public health problem associated with elevated morbidity and mortality within the United States. Current behavioral treatments have limited efficacy and there are currently no FDA approved pharmacological treatments for CUD. Classic psychedelics might be associated with lowered odds of substance misuse and may effectively treat various forms...
Clinics in geriatric medicine
February 1, 2022
Wm Maurice Redden, Saif-Ur-Rahman Paracha, Quratulanne Sheheryar
7 citations
Hallucinogens, or psychedelics, are substances/drugs that have been used for over a millennium. The most well known are LSD, psilocybin, mescaline, and PCP. These substances may induce hallucinations as well as cause somatic and psychological symptoms. Because of the Controlled Substances Act of 1970, there has been very little research done to determine the long-term consequences or perhaps...
Progress in Palliative Care
January 2, 2022
A. C. Garcia, L. O. Maia
The healthcare field and society at large are witnessing a resurgence of interest in the effects and applications of psychedelic therapies in a wide range of settings. In the 1950s and 1960s, research was conducted to explore different applications for psychedelics, such as lysergic acid diethylamide (LSD) and mescaline, in the healthcare setting. However, psychedelic research was dramatically...
Entre trópicos
2022
Mauricio Guzmán, Beatriz C. Labate
Este capítulo apresenta a reflexão sobre os contatos e intercâmbios entre usuários de ayahuasca e de peiote em contextos rituais no México. Diferentemente do que opinam outros autores, os contatos e usos alternados ou combinados dessas substâncias enteógenas não acontecem de forma descontextualizada, constante ou desterritorializada. Essas novas formas revelam negociações ou acordos...
Encyclopedia of Violence, Peace, & Conflict
2022
A. D. Renteln
In a trial in California, Navajo defendants argue that using the hallucinogen peyote to achieve spiritual exaltation is protected by the Constitution's free exercise of religion clause, trumping the states' right to regulate them. An Ibo man from Nigeria sues Pan American World Airways for transporting his mother's corpse in a cloth sack. Her arrival for the funeral facedown in a burlap bag...
Journal of Psychopharmacology
2022
Grant Jones, Matthew K. Nock
40 citations
Background: Depression is a major mental health issue worldwide, with high rates of chronicity and non-recovery associated with the condition. Existing treatments such as antidepressant medication and psychological treatments have modest effectiveness, suggesting the need for alternative interventions. Aim: The aim of this study was to examine the relationships between MDMA...
Current Topics in Behavioral Neurosciences
2022
Matthias E. Liechti, Friederike Holze
35 citations
Classic psychedelics, including psilocybin, lysergic acid diethylamide (LSD), dimethyltryptamine, and mescaline, and entactogens/empathogens, especially 3,4-methylenedioxymethamphetamine, have received renewed attention in psychiatric research and may be developed into medications for such indications as anxiety, depression, cluster headache, and posttraumatic stress disorder, among others....