Progress in Palliative Care
December 1, 2025
M. Barimbing, D. Jeger, Made Edwin Sridana
ABSTRACT This narrative review synthesized the use of psilocybin-assisted therapy as a promising treatment for alleviating death anxiety in terminally ill patients. The insights presented are derived from findings reported in previous studies. Therefore, this review aimed to assess the efficacy, pharmacology, and mechanisms by which psilocybin alters brain function by affecting 5-HT2A receptors...
Progress in Palliative Care
April 1, 2025
Jaime Andrés Vinasco Barco, Ana Cláudia Mesquita Garcia
This article discusses the neologism ‘palliadelic’ to designate the use of psychedelics in palliative care (PC) settings. Combining the concepts of ‘palliative’ and ‘psychedelic’, the term aims to describe interventions that use psychedelic substances to alleviate the psychological, spiritual, and existential suffering of patients with serious or incurable illnesses, or at the end of life....
Progress in Palliative Care
July 3, 2024
A. C. Garcia, Myla Chistie Araujo Custodio Bonifácio, L. O. Maia
The scientific community's interest in psychedelic-assisted therapies (PAT) as a potential new therapeutic modality is growing, as evidence suggests that their use has a significant impact on the outcomes of patients with various conditions, including those with serious illnesses. In the context of PAT, the interpersonal bond established between patient and therapist is a vital factor for the...
Progress in Palliative Care
January 2, 2022
A. C. Garcia, L. O. Maia
The healthcare field and society at large are witnessing a resurgence of interest in the effects and applications of psychedelic therapies in a wide range of settings. In the 1950s and 1960s, research was conducted to explore different applications for psychedelics, such as lysergic acid diethylamide (LSD) and mescaline, in the healthcare setting. However, psychedelic research was dramatically...