The final paragraph of the 20-page chapter "A Brief Review" (and it is, by-and-large, a good review) reads: "We feel that detailed first-hand accounts of experiencesas they occurred(typescripts of tape recordings) by subjects, screened for stability, in sensorilly controlled environments, will help to resolve the question of whether the hallucinogenic experience should be an available adjunct...
Based on the frequently reported similarities between creative and psychedelic (drug-induced, consciousness-expansion) experiences, a preliminary study was conducted to explore the effects of psychedelic agents (LSD-25, mescaline) on creative problem-solving ability. Twenty-seven professionally employed males were given a single psychedelic experience in 1 of 7 small groups ( ns = 3 or 4)...
The use of hallucinogenic (psychotomimetic, dysleptic, psychedelic) substances to produce altered states of consciousness is not new,1-3but recently there has been increased interest and publicity given these agents. This renewed attention has been spurred by the discovery of several new substances, such as d-lysergic acid diethylamide (LSD), psilocybin, and psilocin, which have potencies far...
This paper describes the procedure and results of a new kind of behavior change or rehabilitation program The methods used here may have applications to a wide range of settings in the field of rehabilitation or behavior change. The program aims to produce such changes in prisoners' ways of thinking and living as will enable them to stay out of prison once they are: released. It is well known...
The perception of patterns not resulting from viewing external objects but stimulated by cranial electrodes with pulse currents within the electroencephalographic frequency range (‘phosphenes’) has been investigated in earlier work. The experiments described in this paper were undertaken to observe in one subject effects of chemical stimulation (by mescaline, psilocybin and LSD) on...
Psychotomimetic drugs have been used increasingly in the past decade for facilitating psychotherapy, most experience being with lysergic acid diethylamide (LSD-25) (Sandison, 3; Savage, 4; Abramson, 1; Cohen, 2). Few attempts have been made to study experimentally their effects on therapeutic interviews, largely because of technical difficulties.
Sernyl was administered to 55 patients, chosen at random from the population of a mental hospital. Its disinhibiting potential appears to be related to the dose. Sernyl in doses of 0.07 mgms/kg administered in 7 minutes by the intravenous route activated the patients specific psychopathology to a greater degree than known psychotomimetics (LSD 25 and Mescaline Sulfate). Physiological and...
1. Effect of electroshock and 18 chemical agents (pentylenetetrazole, semicarbazide, strychnine, picrotoxin, caffeine, pheniprazine, amphetamine, mescaline, LSD, phenobarbital, chloral hydrate, acetazolamide, diphenylhydantoin, meprobamate, chlorpromazine, methoxypromazine, reserpine and morphine) was determined on the level of 10 ninhydrin-reacting compounds in the rat brain (glutathione,...
There are, in the main, two principal methods of biological research into the problem of causation of schizophrenia. In the first, or direct method, studies are made of the body fluids and of the metabolism of schizophrenics in the hope of turning up some toxic factor or error of metabolism. Such studies are currently under way in a number of centres and, although many claims as to positive...
It would seem, in fact, that we now have an experimental model of the schizophrenic syndrome superior to the "model psychoses" induced with mescaline or LSD. Not only will perceptual interference reproduce more closely the primary symptoms of schizophrenia, but these disturbances are caused entirely by external manipulation, without the confusion of a toxic psychosis. While of course we cannot...