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John Smythies

7 papers in the library · 413 citations · publishing 1954-2009

Papers

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Philosophy, perception, and neuroscience.

Perception 2009 John Smythies 8 citations

This paper presents the results of some recent experiments in neuroscience and perceptual science that reveal the role of virtual reality in normal visual perception, and the use of television technology by the visual brain. This involves particularly the cholinergic system in the forebrain. This research throws new light on the nature of perception and the relation of phenomenal consciousness...

Requiem for the identity theory

Inquiry September 1, 1994 John Smythies 18 citations

This paper examines the impact that recent advances in clinical neurology, introspectionist psychology and neuroscience have upon the philosophical psycho‐neural Identity Theory. Topics covered include (i) the nature and properties of phenomenal consciousness based on a study of the ‘basic’ visual field, i.e. that obtained in the complete dark, the Ganzfeld, and during recovery from occipital...

Neurophilosophy

Psychological Medicine August 1, 1992 John Smythies 9 citations

Neurophilosophy is Patricia Churchland's (1986) hypothesis that the mind-brain 'problem' and related 'problems' such as those surrounding perception and cognition will be solved by advances in cognitive neuroscience.This entails that the attempts by philosophers to solve these problems by their methods of purely logical, conceptual and linguistic analysis are doomed to failure as they represent...

Behavioural Effects of some Derivatives of Amphetamine and LSD and their Significance

Nature May 16, 1970 John Smythies, J. Beaton, F. Benington et al.

IN attempts to work out possible mechanisms of action of the hallucinogenic drugs, it would be helpful to know which chemical groups modify their activity. In the methoxylated amphetamines, some methoxy groups may act as electrostatic binding sites and some may effect the shape and energy distribution of the π cloud. It may also be important to know whether the amino group is necessary for...

The Comparative Psychopharmacology of Some Mescaline Analogues

Journal of Mental Science April 1, 1960 John Smythies, Carmit Levy 23 citations

There are, in the main, two principal methods of biological research into the problem of causation of schizophrenia. In the first, or direct method, studies are made of the body fluids and of the metabolism of schizophrenics in the hope of turning up some toxic factor or error of metabolism. Such studies are currently under way in a number of centres and, although many claims as to positive...

A New Hallucinogen: 3,4,5-Trimethoxyphenyl-β-Aminopropane

Journal of Mental Science April 1, 1955 Dwight I. Peretz, John Smythies, William C. Gibson 55 citations

3,4,5-Trimethoxyphenyl-β-aminopropane (TMA) is structurally related to both amphetamine and mescaline, as is shown in Figure 1. Because of this structural relationship of TMA and amphetamine, methedrine, and mescaline, one could anticipate a clinical response to the compound which would represent certain phenomena characteristic of each of these drugs. This presented an intriguing problem as to...

Schizophrenia: A New Approach. II. Result of a Year's Research

Journal of Mental Science 1954 A. Hoffer, H Osmond, John Smythies 300 citations

About one year ago, with the encouragement of the Editor-in-Chief, a short paper appeared in this Journal entitled “Schizophrenia; A New Approach” (18). In this paper it was noted that mescaline and adrenaline have a similar biochemical structure. It was suggested that one of the aetiological agents in schizophrenia might be a substance or substances lying between these two; with the...