Transcendental Meditation (TM) is a mental technique using a mantra to facilitate meditation. TM has a potential for treating symptoms of posttraumatic stress disorder (PTSD), but its clinical efficacy remains to be clarified. This pilot study evaluated the acceptability, preliminary effectiveness, and neurophysiology of TM for veterans with PTSD. Twenty-nine veterans (20.7% female) were...
Online mindfulness-based intervention as a feasible and acceptable approach has received mounting attention in recent years, yet more evidence is needed to demonstrate its effectiveness. The primary objective of this study was to examine the effects of online mindfulness-based programs on psychological distress (depression and anxiety). The randomized controlled intervention design consisted of...
PsyArXivOctober 29, 2018Michael C Mullarkey, Mallory Dobias, Karen Bluth
preprint
Disentangling the unique associations of self-compassion and mindfulness with adolescent depression has been an empirical challenge. Taking a symptom-level approach to adolescent depression using network analysis can address some of the most common conceptual and psychometric challenges in this area. Under this network analysis framework, some symptoms are more central, or predictive of the...
La pleine conscience pourrait permettre de réduire l’impulsivité alimentaire et augmenter la motivation à pratiquer des activités physiques, à condition d’être pratiquée quotidiennement par des individus souffrant d’obésité et de trouble de binge eating. L’objectif est de tester l’efficacité d’une intervention à distance basée sur la pleine conscience auprès de patients obèses souffrant de...
Major depressive disorder (MDD) is a highly prevalent and debilitating illness and closely linked to suicide risk. Currently available antidepressants take weeks to work and have low remission rates; indeed, about a third of individuals with MDD fail to fully remit in response to these agents. Novel therapies that target the glutamatergic system—such as ketamine—offer rapid antidepressant...
AIM: Major depressive disorder is a common and debilitating condition with substantial economic impact. Treatment options, although effective, are aimed at relieving the symptoms with limited disease modification. Ketamine, a commonly used anaesthetic, has received substantial attention as it shows rapid antidepressant effects clinically. We studied the effects of ketamine on hippocampal...
BACKGROUND: Mindfulness based interventions (MBIs) are an increasingly popular way of attempting to improve the behavioural, cognitive and mental health outcomes of children and adolescents, though there is a suggestion that enthusiasm has moved ahead of the evidence base. Most evaluations of MBIs are either uncontrolled or nonrandomized trials. This meta-analysis aims to establish the efficacy...
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) frequently co-occur and are associated with worse outcomes together than either disorder alone. A lack of consensus regarding recommendations for treating PTSD-AUD exists, and treatment dropout is a persistent problem. Acceptance and Commitment Therapy (ACT), a transdiagnostic, mindfulness- and acceptance-based form of behavior...
Background: Conventional antidepressants are thought to produce their impact on clinical symptoms by increasing the central availability of biogenic amine neurotransmitters (the monoamine hypothesis of depression). These drugs continue to be the primary medicines used in major depressive disorder. Although they have biological effects after acute dosing, full antidepressant response generally...
ThoraxOctober 18, 2018Ann Marie Parker, Albahi M. Malik, Megan M. Hosey4 citations
Depressive, anxiety and post-traumatic stress disorder (PTSD) symptoms are common, long-lasting and associated with worse quality of life among intensive care unit (ICU) survivors.1–4 There are few clinical trials evaluating interventions to improve these symptoms. Cox and colleagues evaluated the feasibility of a mobile mindfulness training application (App) to address psychological stress...