Die psychedelika assistierte Psychotherapie erfährt aktuell eine wissenschaftlich fundierte Renaissance. Studien zeigen eine therapeutische Wirksamkeit von Substanzen wie Psilocybin, LSD und MDMA bei verschiedenen psychischen Störungsbildern, insbesondere bei therapieresistenter Depression, PTBS, Angstund Suchterkrankungen. In der Schweiz nimmt diese Entwicklung eine besondere Stellung ein: Als...
Social WorkOctober 1, 2025Heidi L Allen, Brooke L Stott
With MDMA, LSD, and psilocybin receiving “Breakthrough Therapy” designation by the U.S. Food and Drug Administration (FDA) and moving into Phase 3 clinical trials, we are closer than ever to legal administration of these compounds for mental health treatment. Research from Lykos, Usona Institute, Mindmed, Compass Pathways, and Johns Hopkins, among others, has shown promising efficacy of the...
Background: Job-related stress and its extreme form, burnout, continue to affect almost half of all frontline healthcare workers and first responders. Current treatments are inadequate. Objectives: To evaluate a model of ketamine-assisted psychotherapy (KAP) delivered in a group format to address symptoms of anxiety, depression, trauma, and burnout via repeated measures of the Generalized...
Rapid changes in the legalized cannabis market have led to the predominance of high-concentration delta-9-tetrahydrocannabinol (THC) cannabis products. To systematically review associations of high-concentration THC cannabis products with mental health outcomes. Ovid MEDLINE through May 2025; EMBASE, Allied and Complementary Medicine Database, Cochrane Library, Database of Abstracts of Reviews...
Psychedelic drugs have garnered increasing attention for their therapeutic potential in treating a variety of psychiatric diseases, such as depression, anxiety, and substance use disorder. The claustrum (CLA), a brain area with remarkable interconnectivity to frontal cortices, has recently been shown to have a dense population of serotonin 2 receptors (5-HT2Rs) that are activated by...
Abstract Background Psychedelic and dissociative drugs, including psilocybin, lysergic acid diethylamide (LSD), 3,4-methylenedioxymethamphetamine (MDMA), and ketamine, have garnered significant interest for their therapeutic potential in treating various mental health disorders. However, their psychoactive properties pose substantial risks when used in contexts requiring unimpaired cognitive...
Ayahuasca is a traditional hallucinogenic concoction utilised by indigenous populations in the Amazon Basin for ages in spiritual and therapeutic rituals. The increasing global popularity is attributed to its alleged medicinal and consciousness-expanding properties. The infusion is primarily composed of two key components: the Banisteriopsis caapi vine and the leaves of Psychotria viridis,...
PLoS OneSeptember 30, 2025Orla Deegan, Mai Yoshitani, Brona M Fullen et al.
Background: Online pain management programmes have evidence as effective interventions for individuals with chronic pain. This study was a one-year exploratory follow-up of a parallel group feasibility randomised controlled trial (RCT) investigating the effectiveness of participating in an online pain management programme that combined Mindfulness-Based Stress Reduction (MBSR) and exercise...
In today's times it is necessary to integrate a holistic understanding of the human body, remembering the importance that mind and emotions have in the physical appearance of the body. The purpose of this paper is to provide a comprehensive overview of the benefits of consistent yoga practice and to assess the results of a few chosen articles that investigate the therapeutic effects of yoga....
Psycho-OncologieSeptember 29, 2025Boxiang Zhang, Boyang Li, Zhiyuan Liang et al.
Patients with head and neck malignancies frequently experience substantial psychological distress and functional impairment during radiotherapy, yet structured interventions targeting both domains are lacking. This prospective controlled study evaluated the effectiveness of an 8-week mindfulness-based intervention (MBI) program on anxiety and functional recovery in individuals undergoing...