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Depression: all studies

Page 545 of 1,034: studies 5,441 to 5,450 of 10,336, newest first. Back to the depression overview

Research

Nonrandomized Open Trial of a Mindfulness- and Compassion-Based Selective Preventive Mobile Health Intervention for Forcibly Displaced People.

Mindfulness October 2, 2025 Shani Zohar Puris, Kim Yuval, Gebreyohans Gebremariam et al.

This study tested the feasibility of Mindfulness-SOS for Refugees, a novel lay- and minimally guided mobile health mindfulness- and compassion-based intervention, that is trauma-sensitive and socio-culturally adapted for diverse forcibly displaced people. A pre-registered, nonrandomized, single-arm, open-trial of Mindfulness-SOS as a selective preventive intervention was conducted during the...

DOI: 10.1007/s12671-025-02675-9 (opens in new tab) Full text (opens in new tab) Covid-19 Forcibly displaced people Mobile health

Naltrexone in the Treatment of Ketamine Use Disorders: A Case Report and Literature Review.

Journal of Addiction Medicine October 2, 2025 Rishi Verma, Tom Colley, Claire Waldock et al. 1 citation

Nonprescribed use of ketamine has increased worldwide due to its hallucinogenic and psychedelic effects. Ketamine use disorders (KUDs) are marked by intense cravings and tolerance, which often trigger relapses and worsen recovery outcomes, defined as sustained ketamine abstinence with reduced cravings, resolved withdrawal symptoms, and improved psychosocial functioning. Currently, there are no...

DOI: 10.1097/adm.0000000000001589 (opens in new tab) Full text (opens in new tab) Ketamine dependence Ketamine desire Naltrexone Substance-related disorders

Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain

Nature Neuroscience October 2, 2025 Ahmad Hammo, Stephen Wisser, Joseph Cichon 20 citations

Chronic pain and mood disorders co-occur, exacerbate one another and share neurobiological mechanisms, but whether a single intervention could promptly alleviate both conditions remains unclear. Here, in two chronic pain models, we show that a single dose of psilocybin induces a rapid and sustained reversal of both mechanical allodynia and anxiodepression-like states in adult male and female...

The Effectiveness of a Mindfulness-Based Art Therapy Program on Sleep Quality among Urban Older Adults in Thailand: A Quasi-Experimental Study

Patient Preference and Adherence October 1, 2025 K. Makkabphalanon, Pramote Thangkratok, Chedhakitd Bunnaphasitthasothin et al.

Background Approximately 50% of older adults experience sleep disturbances. The preservation of high-quality sleep is essential; consequently, there is a pressing need for effective interventions to enhance sleep quality. Purpose This study aimed to determine the effectiveness of the Mindfulness-Based Art Therapy (MBAT) on sleep quality, depression anxiety stress, and mindful attention...

Effects of a 12-Week Yoga and Mindfulness Meditation Program on Psychological Stress, Inflammatory Markers, and Sleep Quality in Middle-Aged Obese Women: A Randomized Controlled Trial

Sport Mont October 1, 2025 Manjula Rathinam, Eswari Varadharajan, Robert Çitozi et al.

Obesity in middle-aged women is commonly linked with chronic inflammation, psychological stress, and poor sleep quality. Holistic, non-pharmacological approaches such as yoga and mindfulness may offer multidimen- sional benefits. This randomized controlled trial investigated the impact of a 12-week yoga and mindfulness meditation program on psychological stress, inflammatory markers, and sleep...

Mind-Body Causal Relationship: Inquiry into Mental Health Disorders and the Limits of Neurobiological Reductionism

Ibom Medical Journal October 1, 2025 EI Archibong, FE Osho, AE Udoh et al.

This paper undertook a critical and exploratory inquiry into how causality in the mind-body relationship has been theorised and operationalised in contemporary mental health discourse. Unlike dominant approaches that prioritised brain-based explanations for psychological disorders, this paper interrogated the ontological and epistemic assumptions underpinning neurobiological reductionism, which...

Interactions between fentanyl and 2,5-dimethoxy-4-methylamphetamine: Ventilatory effects in nonhuman primates.

Journal of Pharmacology and Experimental Therapeutics October 1, 2025 David R Maguire

Increasing interest in the therapeutic potential of psychedelics, combined with expanding availability, decreasing perceived risk, and widening efforts toward decriminalization, underscore the need to investigate potential consequences that might emerge with their use, including interactions that occur when psychedelics are taken in combination with other drugs such as opioids. This study...

The Use of Mindfulness Meditation Apps Improves Mental Health Among Graduate Students

Mindfulness October 1, 2025 Kelly A. Grogan

Abstract Objectives This study sought to determine whether mindfulness meditation training via a simple meditation app can improve well-being among graduate students. Method Graduate students were recruited from STEM programs at the University of Florida. Participants were randomly assigned into treatment and control groups. The control group continued with their typical routines during the...

Psychedelika assistierte Therapie

Psychotherapie-Wissenschaft October 1, 2025 Heiner Dörfler

Die psychedelika assistierte Psychotherapie erfährt aktuell eine wissenschaftlich fundierte Renaissance. Studien zeigen eine therapeutische Wirksamkeit von Substanzen wie Psilocybin, LSD und MDMA bei verschiedenen psychischen Störungsbildern, insbesondere bei therapieresistenter Depression, PTBS, Angstund Suchterkrankungen. In der Schweiz nimmt diese Entwicklung eine besondere Stellung ein: Als...

DOI: 10.30820/1664-9583-2025-2-7 (opens in new tab) Chronic disease Butyrophenone Continuing education Gynecology

Preparing Social Work for Psychedelic-Assisted Therapy.

Social Work October 1, 2025 Heidi L Allen, Brooke L Stott

With MDMA, LSD, and psilocybin receiving “Breakthrough Therapy” designation by the U.S. Food and Drug Administration (FDA) and moving into Phase 3 clinical trials, we are closer than ever to legal administration of these compounds for mental health treatment. Research from Lykos, Usona Institute, Mindmed, Compass Pathways, and Johns Hopkins, among others, has shown promising efficacy of the...