Aim: The present research is to evaluate the antioxidant and antipsychotic potential of Desmodium gangeticum on the ketamine-induced experimental psychosis model in rats with a focus on TNF-α Regulation. Materials and Methods: The root was collected, desiccated, and finely ground. Extraction was conducted using 98% ethanol in a Soxhlet apparatus. This study included a preliminary phytochemical...
Ayahuasca is a traditional hallucinogenic concoction utilised by indigenous populations in the Amazon Basin for ages in spiritual and therapeutic rituals. The increasing global popularity is attributed to its alleged medicinal and consciousness-expanding properties. The infusion is primarily composed of two key components: the Banisteriopsis caapi vine and the leaves of Psychotria viridis,...
Depression is a common mental illness, with an estimated 3.8% of global population affected. Peripheral administration of lipopolysaccharide (LPS) culminate in a distinct depressive-like behavioral syndrome, measured by increased duration of immobility in the forced swim test (FST) and anhedonia in sucrose preference tests (SPT). After 6 days of LPS stimulation, we established a depression...
A persistent 3,4-Methylenedioxymethamphetamine (MDMA) exposure may disrupt the human body serotonergic system which subsequently leads to physical and psychiatric chaos. Serotonin, a well-known monoamine neurotransmitter which is the main target of MDMA can be found in cerebrospinal (CSF) fluid. Its variation reflects the severity of neuronal damage caused by MDMA exposure. Hence, this article...