Traumatic experiences are among the strongest predictors of suicidal thoughts and behaviors, but the mechanisms that account for this association are still debated. Sleep disturbances, particularly insomnia, nightmares, and fragmented sleep, are highly prevalent after trauma and have been shown to predict suicidality independently of depression and other psychiatric comorbidities. This...
PsychoactivesDecember 24, 2025Brendan Driscoll, Shaheen E. Lakhan1 citation
Psychedelic-assisted therapy offers rapid and profound benefits for treatment-resistant psychiatric conditions but remains constrained by the need for intensive, clinic-based administration. Concurrently, advances in digital health technologies have introduced scalable tools. This systematic review evaluates the safety, efficacy, and implementation of digitally enabled psychedelic-assisted...
Ketamine is a traditional anesthetic, which has attracted much attention in recent years for its rapid antidepressant effect. It has performed particularly well in the treatment of patients with intractable depression, marking major breakthrough in the area of mental illness treatment. However, with further research, its potential neurotoxicity has gradually emerged, especially in the case of...
University students worldwide are experiencing a growing mental health crisis, with anxiety, depression, and academic stress undermining well-being and learning outcomes (Auerbach et al., 2018). Mindfulness-based interventions (MBIs) have gained empirical support for reducing psychological distress and enhancing cognitive performance in diverse populations (Kabat-Zinn, 2013; Khoury et al.,...
Abstract With the resurgence of psychedelic research and the growing interest in their therapeutic potential, there is an urgent need to understand how these compounds act across biological sexes. Despite widespread interest in their use for conditions marked by social impairments, including depression, anxiety, and anorexia nervosa, the influence of sex as a biological variable (SABV) on the...
Anxiety, depression, and existential distress are common symptoms in palliative care and significantly impair patients’ quality of life. Psilocybin-assisted therapy, based on preparation, therapeutic support, and psychotherapeutic integration, has emerged as a promising intervention to alleviate this complex cluster of suffering. The aim of this systematic review was to synthesize the evidence...
JURNAL SYIAR-SYIARDecember 20, 2025Dewi Adawiah, Solihah Sari Rahayu, Jamaludin Jamaludin
Contemporary psychological crises, driven by overwhelming productivity demands and existential meaninglessness, reveal the inadequacy of materialistic therapeutic approaches in addressing profound mental health challenges. This investigation examines gratitude as a conceptual bridge connecting positive psychology frameworks with Sufi spiritual traditions, proposing comprehensive therapeutic...
Patients who undergo radical cervical cancer surgery often experience sexual dysfunction and psychological distress, which seriously affects their quality of life. This study aimed to evaluate the clinical effectiveness of mindfulness-based stress reduction (MBSR) therapy for psychosexual adaptation in patients after radical cervical cancer surgery. To systematically evaluate the clinical...
Classic psychedelics such as lysergic acid diethylamide (LSD) and psilocybin induce mild cardiovascular activation in addition to their psychological effects. While these effects are well described in healthy adults, little is known about their dynamics in clinical populations undergoing psychedelic-assisted psychotherapy. This retrospective, observational, single-center study analyzed...