Psychiatry InternationalSeptember 10, 2026Tommaso Barlattani, Giorgio Sernia, Chiara D’Amelio et al.
Background: Evidence for repeated intranasal esketamine in obsessive–compulsive disorder (OCD) remains preliminary, particularly when OCD co-occurs with treatment-resistant depression (TRD). Methods: We report a 58-year-old woman treated with intranasal esketamine in routine clinical care for TRD; change in obsessive–compulsive symptoms was followed as a secondary observational outcome. Her...
Major depressive disorder (MDD) and treatment-resistant depression (TRD) continue to drive interest in ketamine-family compounds and psilocybin, but antidepressant efficacy alone does not establish whether these interventions can be evaluated reliably or implemented responsibly. We conducted a structured narrative review using targeted PubMed/MEDLINE searches through 21 July 2026,...
Psychiatry InternationalJune 15, 2026Angel Labra-Lorenzana, Dania Nimbe Lima Sanchez, Christian Alejandro Delaflor-Wagner et al.
Background: This systematic review and meta-analysis evaluates the efficacy and safety of psilocybin-assisted psychotherapy (PAP) for adults with major depressive disorder (MDD). Methods: A PROSPERO-registered search (CRD42024561979) of CENTRAL, Scopus, PsycINFO, and MEDLINE (2010–2024) identified clinical trials assessing PAP. Risk of bias was assessed using RoB 2 for randomized controlled...
Problematic social media use is associated with adolescents’ mental health, yet mechanisms remain underexplored. This study tested whether dispositional mindfulness mediates associations between problematic social media use and symptoms of depression, anxiety, and stress. In a school-based sample of 892 students aged 10–14 years in Switzerland, participants completed an anonymous online...
Traumatic experiences are among the strongest predictors of suicidal thoughts and behaviors, but the mechanisms that account for this association are still debated. Sleep disturbances, particularly insomnia, nightmares, and fragmented sleep, are highly prevalent after trauma and have been shown to predict suicidality independently of depression and other psychiatric comorbidities. This...
Psychiatry InternationalOctober 13, 2025Felipe Montalva-Valenzuela, Eduardo Guzmán-Muñoz, Gérson Ferrari et al.1 citation
Background: Physical activity is essential for good health and human well-being, yet one-third of adults worldwide fail to achieve the recommended weekly physical activity. Buddhist Walking Meditation (BWM), Walking Meditation (WM), or Mindful Walking (MW) is a mindfulness practice characterized by mind–body interaction, seeking to promote people’s well-being. Therefore, this systematic review...
Nature-based interventions (NBIs) grounded in mindfulness have been shown to be beneficial for improving mental wellbeing in adults. With increasing mental health challenges among children and adolescents, accessible and cost-effective interventions are essential to enhance their well-being. Brief mindfulness-based NBIs may be helpful in this regard, but there is a dearth of evidence testing...
Substance-induced psychosis (SIP) is an increasingly prevalent and complex condition that presents significant diagnostic and therapeutic challenges. With the rising use of novel psychoactive substances (NPSs) and potent traditional compounds like cannabis and cocaine, particularly among adolescents and young adults, understanding the mechanisms and clinical manifestations of SIP has become...
Background: Piperazines, synthetic compounds known for their stimulant and hallucinogenic effects, have gained prominence among novel psychoactive substances (NPS) and are frequently associated with adverse psychiatric outcomes, including psychosis. Methods: A systematic review of the literature available up to 23 May 2024 was conducted, using the PubMed, Scopus, and Web of Science databases,...
International psychiatry is facing major challenges due to the rapid increase in mental health issues. The forthcoming mental health crisis has opened the debate about the need to broaden the therapeutic horizons with the implementation of digitally assisted mindfulness practices within psychotherapeutic interventions. Mindfulness training is developing into a promising intervention for a...
Psychiatry InternationalDecember 7, 2022Clara R. Kretschmer, Burcu Göz Tebrizcik, Eleanor J Dommett
Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental condition impacting children and adults. Current treatments are limited and there is increasing interest in the use of mindfulness, which is growing in popularity. Previous systematic reviews have typically focused on specific ages, outcome measures or interventions. The current review aimed to take a more...