Depression and Anxiety
January 30, 2015
Monika A Waszczuk, Helena M. S. Zavos, Elena Antonova et al.
Background: Mindfulness-based therapies have been shown to be effective in treating depression and reducing cognitive biases. Anxiety sensitivity is one cognitive bias that may play a role in the association between mindfulness and depressive symptoms. It refers to an enhanced sensitivity toward symptoms of anxiety, with a belief that these are harmful. Currently, little is known about the...
Journal of Affective Disorders
January 15, 2015
Giovanni Stanghellini, Andrea Raballo
It is a current trend in psychiatry to discard the Kraepelinian dichotomy schizophrenia vs. manic-depressive illness and use the overinclusive label 'psychosis' to broadly indicate the whole spectrum of severe mental disorders. In this paper we show that the characteristics of psychotic symptoms vary across different diagnostic categories. We compare delusions in schizophrenia and major...
Frontiers in Psychology
January 12, 2015
Alberto Amutio, Clemente Franco, María de Carmen Pérez-Fuentes et al.
Fibromyalgia is a disabling syndrome. Results obtained with different therapies are very limited to date. The goal of this study was to verify whether the application of a mindfulness-based training program was effective in modifying anger, anxiety, and depression levels in a group of women diagnosed with fibromyalgia. This study is an experimental trial that employed a waiting list control...
PeerJ
2015
Emma L Barratt, Nick J Davis
Autonomous Sensory Meridian Response (ASMR) is a previously unstudied sensory phenomenon, in which individuals experience a tingling, static-like sensation across the scalp, back of the neck and at times further areas in response to specific triggering audio and visual stimuli. This sensation is widely reported to be accompanied by feelings of relaxation and well-being. The current study...
Archives of gerontology and geriatrics
2015
Astrid Norberg, Berit Lundman, Yngve Gustafson et al.
The aims of this study were to describe the associations between ST and psychological and physical wellbeing among oldest old people and to test the influence of negative life events on ST, and the predictive value of the self-transcendence scale (STS) for mortality. ST has been identified as a valuable resource for transcending psychological and physical suffering and has been related to...
Integrative Cancer Therapies
2015
C. Eyles, G. Leydon, C. Hoffman et al.
The impact of living with metastatic breast cancer (MBC) is considerable and psychosocial support can be beneficial. Mindfulness-based stress reduction (MBSR) can help self-management of anxiety, depression, quality of life (QoL), and fatigue and has been evaluated in early-stage breast cancer but not MBC. This study investigated the acceptability and feasibility of providing MBSR for women...
RAND Corporation eBooks
2015
Melony E. Sorbero, Sangeeta C. Ahluwalia, Kerry A. Reynolds et al.
RAND researchers conducted a systematic review that synthesized evidence from randomized controlled trials of mindfulness-based cognitive therapy — used adjunctively or as monotherapy — to assess its efficacy and safety in treating adults with major depressive disorder (MDD).
2015
S. Verma
Background and Objective: The objective was to evaluate clinical trial data on the use of ketamine in treating treatment-resistant depression (TRD). Materials and Methods: PubMed search (November 2012) was initiated using the keywords: Ketamine, resistant depression. Inclusion criterion included: English language publications describing clinical trial reports on humans with TRD. Results: A...
Neural Plasticity
2015
Annie J. Xu, Mark J. Niciu, Nancy B. Lundin et al.
27 citations
Ketamine and lithium both inhibit glycogen synthase kinase 3. In addition, lithium and ketamine have synergistic antidepressant-like effects at individually subeffective doses in rodents. We hypothesized that ketamine's antidepressant effects would be improved by therapeutic doses of lithium versus valproate and that serum lithium levels would positively correlate with ketamine's antidepressant...
Frontiers in Psychiatry
2015
Charles F Zorumski, Peter Nagele, Steven Mennerick et al.
Major depressive disorder (MDD) remains a huge personal and societal encumbrance. Particularly burdensome is a virulent subtype of MDD, treatment resistant major depression (TMRD), which afflicts 15-30% of MDD patients. There has been recent interest in N-methyl-d-aspartate receptors (NMDARs) as targets for treatment of MDD and perhaps TMRD. To date, most pre-clinical and clinical studies have...
Depression Research and Treatment
2015
Basant Pradhan, Tapan Parikh, Ramkrishna Makani et al.
24 citations
Depression affects about 121 million people worldwide and prevalence of major depressive disorder (MDD) in US adults is 6.4%. Treatment resistant depression (TRD) accounts for approximately 12–20% of all depression patients and costs $29–$48 billion annually. Ketamine and repetitive transcranial magnetic stimulation (rTMS) have useful roles in TRD, but their utility in long term is unknown. As...
Frontiers in Pharmacology
2015
Eduardo R Butelman, Mary Jeanne Kreek
3 citations
correction
In the original review, we placed an incorrect citation in a sentence. The correct sentence and citation are as follows: "Also, salvinorin A can act as a “punisher” to self-administration of cocaine or a short-acting MOPr agonist in primates (when given contingently; Freeman et al., 2014).” The authors apologize for the mistake. This error does not change the scientific conclusions of the...