The purpose of the article: In recent years, a renewed interest has emerged in investigating the use of MDMA in the treatment of mental disorders. However, knowledge about the characteristics of recreational use of MDMA, its contexts and effects are limited. Methods: We recruited adult Norwegian participants aged 18 to 65 who reported having had a memorable experience after using MDMA. They...
Abstract Rationale: Individual variability in psilocybin response is a major challenge for psychedelic-assisted therapy, with structural brain features potentially serving as predictive biomarkers. Lewis et al. (2020) reported that rostral anterior cingulate cortex thickness predicted emotional experiences under psilocybin, suggesting cortical morphometry as a marker of psychedelic...
Psychedelics have recently grown in scientific interest, among this, there have been promising findings regarding its potential to treat a range of health problems (such as depression, anxiety, PTSD). Despite the growing research interest in psychedelics, there is little research investigating the effects of microdoses: tiny doses that produce sub-hallucinogenic effects. Additionally, there is...
Chronic psychosocial stress may exacerbate inflammation and oxidative stress, potentially contributing to the aetiology of many lifestyle-related diseases, including elevation of blood pressure (BP) and increased cardiovascular risk. Mindfulness-based stress reduction (MBSR) improves psychological well-being, but few studies have investigated its effect on biological parameters related to...
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study. Setting Outpatient public stimulant treatment program at St. Vincent's Hospital, Sydney,...
In recent years, the Mindfulness-Based Stress Reduction Program has been implemented in pregnant women to cope with mental problems such as anxiety and depression, reduce fear of childbirth, alleviate physical symptoms, strengthen the bond between mother and baby, increase self-compassion and self-efficacy levels, and reduce the risk of postpartum depression. Mindfulness involves paying...
Emergency department nurses face severe occupational stress leading to anxiety, depression, and burnout, which significantly impair their well-being and patient-care quality. This narrative review examined the role of mindfulness-based stress reduction (MBSR) in addressing these challenges. Rooted in nonjudgmental present-moment awareness, MBSR enhances emotional regulation and reduces...
Introduction Aesthetic experiences under psychedelics are often described as vivid, emotionally powerful, and meaningful, yet they remain under-measured in psychometric research. This study aimed to refine and validate the Psychedelic Aesthetic Experience Questionnaire (PAEQ), a novel instrument designed to assess the aesthetic dimensions of acute psychedelic experiences. Methods A total of 365...
Background: Evidence is growing that psychedelic substances have positive effects in the setting of Palliative Care (PC), focusing on special needs in this patient population. After a scoping review of the literature, no published expert recommendations guiding best practice for psychedelic-assisted therapy (PAT) towards the end of life were identified. Objective: To draw conclusions from...
September 11, 2025Rakesh Kumar, Dushyant Kumar Singh
Electroencephalography-based emotion recognition remains an active research area. Unlike many existing pipelines that rely on large, redundant feature sets, we propose a streamlined yet robust framework to examine the influence of chanting the Hare Krishna mantra (HKM) and its musical rendition (Kirtan) on neuronal dynamics-a relatively unexplored direction. EEG signals were acquired using a...