Ramana V. Vishnubhotla, Preeti U. Reed, Balachundhar Subramaniam
preprint
A bstract Background Isha Kriya (IK) is a widely available meditation practice that incorporates breathing regulation that has shown to improve self-reported symptoms of stress, anxiety, and depression. An increasing amount of research has been published on the effects of various meditative practices on scalp electroencephalography (EEG). However, the effects of IK on cortical activity have not...
Julia C. Basso, Sarah Lynn
BACKGROUND Mindfulness and meditation have a rich historical tradition, and a growing scientific base of evidence supports their use in creating positive psychological and neuroplastic changes for practitioners. Though meditation can be taught in various ways, the scientific community has yet to systematically study different types of meditation on neuropsychological outcomes, especially as it...
Harman Brar
Virtual reality has recently been utilized in a therapeutic tool within the area of psychotherapy. VR therapy has become a significant approach to a number of psychological disorders such as anxiety, PTSD, and depression through exposure therapy and simulated environments (Park et al., 2019). However, the potential to mimic psychedelic experiences through VR simulations as a therapeutic...
Stephen Bright, Eyal Gringart, Emily Blatchford et al.
preprint
Objective: The current study aimed to explore whether the subjective effects of microdosing psychedelics are comparable to those of yoga in relation to psychological wellbeing, depression, anxiety and stress. It also aimed to explore the relationship between yoga, microdosing and personality variables including neuroticism, openness and absorption.Method: The sample comprised 339 participants,...
Matthias Forstmann, Christina Sagioglou
preprint
After decades of stagnancy, research on psychedelic substances (such as LSD, psilocybin or DMT) has experienced a renaissance over the last 10 years, with various major research programs being conducted across Europe and the United States. This research primarily investigates the potential of psychedelics in the treatment of mental health disorders, their short and long term effects on...
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Kainat Riaz, Sejal Suneel, Mohammad Hamza Bin Abdul Malik et al.
1 citation
preprint
Post-traumatic stress disorder (PTSD) is a debilitating mental health disorder that causes significant dysfunction in individuals. Currently, there are many approved Pharmacotherapy and Psychotherapy treatment options for PTSD, but unfortunately, half of the patients do not respond to traditional therapies. In this article, we reviewed clinical trials and research on...
Kenneth Shinozuka, Burton J. Tabaac, Alejandro Arenas et al.
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Background: After becoming notorious for its use as a party drug in the 1980s, 3,4-methylenedioxy-methampetamine (MDMA), also known by its street names “molly” and “ecstasy,” has emerged as a powerful treatment for post-traumatic stress disorder (PTSD). Areas of uncertainty: There is extensive data about the risk profile of MDMA. However, the literature is significantly biased. Animal models...
Research Square
Taqwa B. Thanoon, Zeina A. Althanoon
preprint
Abstract Maternal depression during pregnancy adversely affects offspring neurodevelopment and behaviour. Typical antidepressants like selective serotonin reuptake inhibitors have limitations due to risks of crossing the placenta. Ketamine has emerged as a promising alternative treatment. This research examined ketamine's effects on offspring of maternally stressed mice. Dams were divided into...
Bryce D. Beutler, Kenneth Shinozuka, Burton J. Tabaac et al.
preprint
Background: Lysergic acid diethylamide (LSD) is a hallucinogenic agent. In the mid-20th century, it was used to augment psychoanalysis and to treat alcohol use disorder. However, LSD was banned in 1970 in part due to concerns that it could bring about or exacerbate mental illness. Its therapeutic potential remains incompletely understood.Areas of Uncertainty: While uncontrolled recreational use...
Research Square
Katelyn Halpape, Raelle Pashovitz, Annabelle Wanson et al.
preprint
Abstract Background Ketamine is a promising therapy for treatment-resistant depression due to its rapid onset, although benefits are often transitory, with patients needing maintenance therapy to prevent relapse. Most data supporting ketamine for treatment-resistant depression refers to the intravenous route of administration, leaving alternative routes lacking in data, especially as...