Abstract Background and Aims Mental health challenges such as depression, anxiety, and existential distress are common among individuals with terminal illness. Preliminary evidence suggests that death acceptance may protect against these issues, but there is limited research on the role of psychedelic-assisted therapy in fostering death acceptance. This scoping review aims to explore the...
Pregnancy is a complex period during which women experience profound physical, emotional, and social changes. Hormonal fluctuations, physiological transformations, and environmental factors during pregnancy can contribute to a range of psychosocial and psychiatric issues, such as stress, fear of childbirth, anxiety, and depression. In recent years, mindfulness-based approaches have been...
Introduction: Psilocybin therapy has demonstrated efficacy for cancer-related anxiety and depression, but resource-intensive individual treatment models raise important questions for psychedelic public health about equitable access and scalability. In our prior Phase 1/2 study of group retreat psilocybin therapy for patients with metastatic cancer, we observed partial responders who did not...
TrialsApril 13, 2026Fanshan Huang, Weiwei Wang, Xin Miao et al.
Traumatic amputations are common traumatic injuries that require digital replantation to restore the form, function, and sensation of the hand. The post-surgical survival of replanted digits is influenced by multiple factors, including psychological factors such as posttraumatic stress disorder (PTSD), anxiety, and depression. Mindfulness-based cognitive therapy (MBCT) is considered a potential...
Family caregivers (FCGs) of cancer patients play a critical role in providing emotional and physical support. Mindfulness-based interventions (MBIs) have been increasingly explored as a potential approach to improving the psychological well-being of FCGs. However, the caregiving burden often results in significant psychological distress, including stress, anxiety, and depression. This...
Mindfulness-based interventions (MBIs) have been consistently associated with reductions in perceived stress and anxiety. One proposed mechanism underlying these effects involves a shift toward parasympathetic dominance during stress exposure, facilitating enhanced emotion regulation and physiological adaptability; however, empirical evidence on this mechanism remains inclusive. In this...
This study examines the application of mindfulness techniques through group counselling to reduce academic stress among students at SMA Negeri 18 Makassar. The objectives of this study are: (1) to describe the level of academic stress experienced by studenst at SMA Negeri 18 Makassar; (2) to determine how the application of mindfulness techniques can help students manage academic stress; and...
Background: Stress is a natural response to challenging situations, affecting people worldwide, with higher prevalence during the pandemic. Studies show that professional students, especially in medical and engineering fields, experience more stress. Ayurveda links mental strength, or Sattvabala, to overall well-being, emphasizing its role in maintaining calmness and resilience. Acharya Charaka...
Cannabinoids, such as Δ9-tetrahydrocannabinol (THC), produce anxiety at high doses, yet the underlying neural mechanisms remain poorly understood. The anterior cingulate cortex (ACC) sends dense monosynaptic projections to the dorsomedial striatum (DMS). Optogenetic excitation of the ACC → DMS pathway promotes anxiolytic-like behavior, suggesting that its suppression could induce anxiogenic...
As psychedelic use increases and integrates with mainstream medicine, understanding the prevalence and nature of postpsychedelic adverse outcomes is critical. We investigated extended difficulties after psychedelic use via the Global Psychedelic Survey (GPS) 2025, which is a multilingual online survey of people who have used psychedelics. Data on the prevalence, characteristics, and...