Chronic stress and nervous system dysregulation disproportionately affect women worldwide, with the 2024 Ipsos World Mental Health Day survey reporting that 66% of women globally experience stress that impairs daily functioning, compared with 58% of men. Despite this documented burden, access to body-centered, non-pharmacological forms of support remains limited, and the mechanisms through...
Background: Cancer patients undergoing radiotherapy frequently encounter high levels of distress, anxiety, depressive symptoms, which reduced quality of life (QoL). Mindfulness-Based Cognitive Behavioural Therapy (MB-CBT) integrates mindfulness principles along with cognitive restructuring and has become a potential intervention. Objective: To systematically review evidence on effectiveness of...
With the resurgence of psychedelic research and growing evidence of their therapeutic potential, there is an urgent need to understand how these compounds act across biological sexes. Despite widespread interest in their use for conditions marked by social impairments, including depression, anxiety, and anorexia nervosa, the influence of sex as a biological variable on the prosocial effects of...
medRxiv Preprint ServerMay 23, 2026Lisa Maria Jöbstl, Bente Lubahn, Ebru Kaya et al.
preprint
Background While growing enthusiasm for the therapeutic potential of classic psychedelics has led to a rise in non-clinical use, attention to persisting adverse effects has emerged with delay. A subset of individuals reports persisting complications such as hallucinogen persisting perception disorder (HPPD), depersonalization/derealization disorder (DDD), anxiety and depression. Yet few medical...
Background Posttraumatic stress disorder (PTSD) remains a challenging condition to treat. Nonpsychedelic pharmacotherapies have modest efficacy, and trauma-focused therapies such as Cognitive Behavioral Therapy (CBT) and Eye Movement Desensitization and Reprocessing (EMDR) demonstrate higher response rates than medications, yet they suffer from high dropout rates (25–35%) and limited...
Opioid dependence is a public health concern in New Zealand, with limited treatment options beyond opioid substitution therapy (OST). Ibogaine, a psychoactive alkaloid with reported anti-withdrawal and anti-craving effects for opioid dependence, is legally available by prescription in New Zealand, offering a context for exploring user experiences. A qualitative collective case study design was...
Depersonalization is usually reported as a manifestation in other psychiatric disorders such as psychosis, anxiety, or depression; in physical trauma; or in drug addiction. But it has been very little reported in clinical descriptions relating to bodily injuries such as diabetic foot. This article focuses on the case of four Cameroonian adults with diabetic foot and presenting clinical...
Academic stress is a serious issue for adolescents' mental health during higher secondary exams, and career-related uncertainty has reached its peak. Over-involvement in school can negatively affect attention span, sleep schedule, motivation, and, consequently, academic performance and overall health. Yoga and meditation are low-cost, culturally relevant mind–body strategies that can be...
Revista fisio&terapiaMay 21, 2026Flávia Saletti Grecco Dotoli, Isadora Piccolo Estevo
Mindfulness has become one of the most relevant approaches for promoting mental health in contemporary society, being widely applied in clinical, educational, and organizational contexts. It is characterized by the ability to focus attention on the present moment intentionally and without judgment, promoting greater awareness of internal and external experiences. This article aims to analyze...
Abstract Background Psychedelic consumption in naturalistic settings is rising, and a significant minority of users experience extended psychological difficulties. Yet, research exploring these challenges remains limited. Despite widespread endorsement of integration practices, little is known about how therapists approach integration for heterogeneous extended difficulties. Methods Nineteen...