Psikiyatride Güncel Yaklaşımlar
September 30, 2025
Mahir Mutlu, Çağrı Öven, Bilge Sena Kurt et al.
Ketamine and esketamine show potential for treating treatment-resistant depression and improving certain cognitive functions, though effects depend on dose and duration. Randomized controlled trials indicate that a 0.5 mg/kg ketamine infusion improves visual memory, processing speed, working memory, and attention in patients who respond. However, long-term ketamine use may harm spatial working memory. Esketamine, an NMDA receptor antagonist, provides rapid antidepressant effects and stabilizes or improves cognition, but high doses may be neurotoxic and impair cognition. Both drugs require more research on long-term safety.
Psikiyatride Güncel Yaklaşımlar
May 31, 2015
Feride Karacaer
Many individuals with major depressive disorder do not respond adequately to standard antidepressants, which also have a delay of weeks before therapeutic effects emerge. Recent studies show that a subanesthetic dose of ketamine is efficacious and safe for treating depression, though its antidepressant effects are short-lived. Psychotomimetic properties may limit ketamine's use in depressive patients. Future research should focus on identifying predictors of response, investigating different doses and routes of administration, and maintaining the antidepressant effect.
Psikiyatride Güncel Yaklaşımlar
April 14, 2026
Ebru Sağıroğlu, Esmanur Körsü
Mindfulness-based programs such as Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Childbirth and Parenting (MBCP) reduce stress, anxiety, and depressive symptoms during pregnancy, and also lessen fear of childbirth, improve childbirth-related self-efficacy, and strengthen maternal-fetal attachment. Some evidence indicates these practices positively influence body image, increase self-compassion, and support adaptation to breastfeeding after birth. Mindfulness-based interventions appear to be promising tools for promoting psychological and physical well-being during pregnancy, though further research on long-term effects is recommended.
Psikiyatride Güncel Yaklaşımlar
November 2, 2024
Melike Dişsiz, Duygu Özer
A systematic review of 26 randomized controlled trials found that mindfulness-based practices improve perinatal and postpartum women's mental health by reducing fear of childbirth, depression, anxiety, and stress, while enhancing psychological well-being, self-efficacy, self-compassion, and mindfulness. The most common intervention was online self-help programs. Physical health benefits included higher rates of normal vaginal births, increased maternal-fetal attachment, lessened birth pain, reduced need for medication or anesthesia, and support for healthy lifestyle behaviors. These findings suggest mindfulness interventions positively influence both maternal and infant mental health.
Psikiyatride Güncel Yaklaşımlar
May 30, 2020
Ege Tekgün, Burak Erdeniz
Bodily self-consciousness—the awareness of one's own body—depends on how the brain dynamically processes and integrates multisensory signals such as vestibular and somatosensory information. Recent research shows that the perception of body parts and the whole body can shift based on whether signals from different senses are congruent. This article reviews experimental methods used to study bodily self-consciousness, discusses the underlying sensory processes, and identifies limitations in prior studies.