American Journal of Psychiatry
September 1, 1958
Herman C. B. Denber
6 citations
Psychodynamic observations made during the mescaline-induced state in 124 patients are reviewed. Mescaline produces a "state of being" in which the clinical spectrum can range from sleep to rage and from normalcy to thoroughly disorganized mental states. Anxiety is considered the background upon which the mescaline experience evolves. One may consider the mescaline-induced state under three...
A M A Archives of Neurology & Psychiatry
November 1, 1956
Harris Isbell
112 citations
The striking mental changes induced by the diethylamide of lysergic acid (hereafter referred to as LSD) have been studied extensively in Europe,* Great Britain,† and the United States.‡ In minute doses (20γ to 120γ) LSD induces a peculiar mental state characterized by anxiety, signs of autonomic dysfunction, perceptual distortion (chiefly visual), alterations in mood and affect, synesthesias,...
American Journal of Psychiatry
June 1, 1952
Charles Savage
137 citations
Lysergic acid diethylamide (LSD-25 Sandoz) given orally in single doses as low as 20 micrograms produces depersonalization, derealization, and increased imagery in "normal" individuals. Larger doses are required to produce the same effect in psychotic patients. Of 15 patients with depressive reactions, 3 recovered and 4 improved after one month's treatment with daily oral doses of 20-100...
Psychosomatic Medicine
October 1, 1942
Morton A. Rubin, William Malamud, Justin M. Hope
24 citations
Mescaline, cocaine, sodium amytal and benzedrine were given to 14 schizophrenic patients, and their influence upon personality functions and the electroencephalogram (EEG) was observed. Changes in the EEG were found only when definite psychological changes took place. The effects of the drugs could be classified into two types: 1) Those specific for a given drug. Psychologically these were...
Pakistan Journal of Positive Psychology
October 31, 2026
Shazia Jabeen, Farah Iqbal
The present study investigated the predictive role of trait mindfulness in relation to depression, anxiety, and stress among Pakistani young adults. The following hypotheses were formulated: H1: Trait mindfulness will significantly and negatively predict depression among Pakistani young adults. H2: Trait mindfulness will significantly and negatively predict anxiety among Pakistani young adults....
BMC Psychology
October 30, 2026
Jingqian Wang, Peirui Wang, Jiaonan Liu et al.
Stress is a psychophysiological response that occurs when environmental demands exceed an individual’s coping capacity, and it is closely linked to many psychosomatic disorders. Mindfulness training can effectively reduce stress, but conventional mindfulness training (CM) places high demands on self-monitoring ability, which limits its effect. Neurofeedback-augmented mindfulness training (NM)...
Revista Tópicos.
October 30, 2026
Maria Eduarda Ribeiro Garcia, Juliana Evangelista Bezerril, Enzo Santos Cunha et al.
A dor crônica constitui uma condição multifatorial que interfere na funcionalidade, na qualidade de vida e nos aspectos emocionais do indivíduo, exigindo estratégias terapêuticas integradas. Este estudo analisa a utilização da meditação, especialmente das práticas baseadas em mindfulness, como estratégia complementar no manejo da dor crônica. Trata-se de uma revisão integrativa da literatura,...
Frontiers in Cardiovascular Medicine
October 30, 2026
Jiawei Lin, Changqun Lian, Guiting Zhou et al.
Background Psychological distress is common in hypertension and may impair disease management. Mindfulness-based interventions have been proposed to improve emotional and health-related outcomes, but evidence in this population remains limited. Methods This systematic review and meta-analysis followed PRISMA guidelines. PubMed, Embase, Web of Science, the Cochrane Library, and CNKI were...
Revista Tópicos.
October 30, 2026
Enzo Santos Cunha, Marco Loyola Machado Leão, Maria Eduarda Ribeiro Garcia et al.
A meditação, especialmente nas intervenções baseadas em mindfulness, tem sido investigada como recurso complementar para a promoção da saúde mental e o manejo do sofrimento psíquico. Este estudo teve como objetivo analisar sua influência sobre sintomas de ansiedade, depressão e estresse e sobre aspectos cognitivos e psicofisiológicos. Realizou-se uma revisão integrativa da literatura, com...
BMC Medicine
October 30, 2026
Jiayi Lin, Fei Cheng, Lei Guo et al.
Abstract Background Impaired inhibitory control under negative affect is a core mechanism sustaining alcohol use disorder (AUD), but receives limited attention in treatment development. Mindfulness meditation has shown efficacy in improving this function, but outcomes differ across individuals. Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive neuromodulation approach...