To explore the associations between mindfulness, psychological distress, and health-related quality of life (HRQOL), and examine whether psychological distress mediates the association between mindfulness and HRQOL in individuals with Parkinson's disease (PD). This is a secondary analysis of baseline data from a clinical trial investigating mindfulness-based interventions in patients with...
Introduction: The return to normal life following the COVID-19 pandemic was evaluated in terms of anxiety upon awakening, sleep quality indicators, and dream characteristics. Methods: The sample comprised 394 women and 107 men who completed an online self-report questionnaire between August 15, 2022, and December 8, 2022 about their sleep and dream experience from the previous night....
Abstract Rationale: Major depressive disorder (MDD) shows marked sex differences in prevalence, symptomatology, and treatment response. However, women remain underrepresented in many clinical trials, and sex-specific treatment outcomes are rarely examined. Objectives This study reanalyzed data from a randomized controlled trial comparing psilocybin and escitalopram for MDD to evaluate sex...
The growing recognition of affective factors in mathematics learning has positioned mindfulness interventions as a promising approach to mitigating mathematics anxiety and enhancing academic performance. Despite increasing scholarly attention, the research landscape remains fragmented, with limited synthesis of publication trends, influential works, thematic developments, as well as global...
Rapid urbanization and unequal urban-rural development have driven large-scale internal migration in low- and middle-income countries, placing internal migrant children at increased risk for psychological distress and sociocultural marginalization. Although schools are critical settings for prevention, targeted interventions that support migrant students' psychological ("feeling well") and...
Background: Depression, anxiety,, and PTSD are leading global causes of disability. Standard interventions utilize slow mechanisms of action, high attrition, and significant accessibility barriers. While intravenous (IV) and intranasal ketamine are rapid-acting alternatives, high cost and intensive logistical requirements limit adoption. Sublingual (SL) at-home ketamine addresses some gaps but...
Zebrafish larvae are increasingly used in behavioural pharmacology because of their translational relevance and suitability for anxiety- and stress-related studies. However, it remains unclear whether commonly used behavioural assays and molecular stress markers provide convergent evidence of anxiolytic-like drug activity. This study therefore aimed not to validate a single predictive screening...
Breathing meditation (BM), particularly when delivered via virtual reality (VR), has shown promise in reducing anxiety and stress and enhancing mindfulness. Recent evidence suggests that embedding rhythmic elements, such as temporally structured inhalation, exhalation, and breath-holding, may further regulate BM’s effectiveness. However, the specific role of rhythm in VR-based breathing...
Background: Post-traumatic stress disorder is frequently accompanied by persistent anxiety, hyperarousal, sleep disturbance, and impaired emotional regulation. Mindfulness-based interventions may support trauma-exposed patients by improving present-moment awareness, distress tolerance, and regulation of intrusive thoughts and bodily arousal. Objective: This study evaluated whether an eight-week...
Abstract Background Mindfulness is reliably associated with lower anxiety and depression, yet the longitudinal within-person dynamics and potential differences between these two forms of emotional distress remain largely unknown. Methods A total of 1,138 participants completed five waves of self-report assessments at two-week intervals. Mindfulness, anxiety, and depression were measured at each...