Floatation-REST (Reduced Environmental Stimulation Therapy) systematically alters sensory and bodily input by combining neutral buoyancy, thermal and proprioceptive neutrality, attenuation of exteroceptive stimulation, and enhancement of cardiorespiratory signaling to the brain. Here we examined whether this non-pharmacological sensory perturbation induces altered states of consciousness and...
Anxiety disorders are among the most prevalent and disabling mental health conditions and are associated with impairments in quality of life (QoL). Previous studies have examined medicinal cannabis for anxiety and QoL using short-term follow-up or cross-sectional surveys. However, there is little longitudinal qualitative research examining how patients experience QoL changes. To explore the...
This study looks at the efficacy of the Mindfulness-Based Stress Reduction (MBSR) program in reducing psychological stress for parents of children with all developmental disabilities. A one–group pre test – post test quasi experimental design was used. Participants in the MBSR intervention program for 8 weeks were the 35 parents (25-45 years) who were in the sample. The Depression Anxiety...
Background: Late-life depression (LLD) is a growing public health concern in aging populations. Although digital mindfulness interventions show promise for depression, anxiety, and insomnia, their efficacy and electroencephalogram (EEG) correlates in older adults with LLD remain unclear. This study evaluated the FocusZen Mindfulness Stress Reduction System, a digital mindfulness intervention...
Abstract This quasi-experimental study investigated the effectiveness of mindfulness-based cognitive therapy (MBCT) and virtual reality-based worry exposure therapy (VR-WET) on cognitive avoidance and emotional capital in adolescents with social anxiety. In Ahvaz, Iran, 60 adolescents aged 12–18 years were randomly assigned to MBCT (n = 20), VR-WET (n = 20), or a no-treatment control group (n =...
Background: Burnout syndrome has become endemic to healthcare professions and is characterized by emotional exhaustion, depersonalization, and a diminished sense of accomplishment. The COVID-19 pandemic introduced additional burdens to pre-existing stressors and has left the global healthcare workforce, including those in India, with an ongoing psychological crisis. Objective: The aim of this...
Background: ±3,4-methylenedioxymethamphetamine (MDMA) has positive effects on socio-emotional processing and MDMA-Assisted Therapy (MDMA-AT) showed promise for treating SAD in a previous placebo-controlled trial. Aims: Develop a preliminary estimate of clinical response and safety for MDMA-AT versus waitlist in adults with SAD. Secondary aims included refinement of a standardized psychotherapy...
Psilocybin has demonstrated promise for improving depressive symptoms in treatment-resistant depression, but its effects on anxiety, quality of life, functioning, and posttraumatic stress symptoms are less well studied. This study reports exploratory findings from an open-label trial in Veterans with TRD. Participants received a single 25-mg dose of psilocybin administered with psychological...
Provided herein are novel 5,6-bicyclic compounds as 5-HT2A receptor agonists, pharmaceutical compositions, use of such compounds in treating depression, anxiety, substance abuse and headaches, and processes for preparing such compounds.
Menopause is a natural phase in a woman's life marked by the cessation of ovarian function and hormonal changes in estrogen and progesterone, often accompanied by physical and psychological symptoms such as anxiety, stress, and depression. One possible way to deal with these changes is to practice mindfulness, especially Islamic mindfulness, which is in line with Islamic values. This study aims...
Les interventions basées sur la pleine conscience (IBPC) sont reconnues comme des approches pertinentes auprès de personnes vieillissantes à risque de déclin cognitif. Toutefois, peu d'études ont exploré l'expérience vécue de participants présentant un déclin cognitif accompagné de symptômes anxiodépressifs. Cette étude qualitative vise à comprendre l'expérience de 13 adultes de 55 ans et plus...
Ketamine and esketamine ("es/ketamine") treatment protocols have been investigated in patients' samples with treatment-refractory anxiety disorders. We systematically reviewed publications in which es/ketamine was used to treat anxiety symptoms in the context of either Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) anxiety disorders or treatment-resistant...
Introduction Eco-anxiety—though not a formal diagnosis—captures climate-related distress overlapping with anxiety-spectrum processes. While mindfulness is often framed as protective, facet-level links to eco-anxiety are underexplored in Central/Eastern Europe. Ecological connectedness may also heighten sensitivity to environmental threat. We examined how mindfulness facets and nature...
Athletes engaged in high-level competition routinely face considerable psychological challenges. Among these, anxiety stands out as a widespread concern that not only undermines athletic output but also compromises both mental and somatic health. Over the past ten years, Mindfulness-Acceptance-Commitment Therapy (MAC), a leading example of third-wave cognitive-behavioral approaches, has drawn...
e24132 Background: Meditation has been associated with reductions in anxiety among cancer survivors. This study aims to evaluate four meditation techniques for reducing anxiety after acute stress in cancer survivors. Methods: Cancer survivors without significant meditation experience treated with surgery alone were randomized to one of the four arms: breathing, focused attention, mindfulness,...
European PsychiatryJune 1, 2026N. Aguayo-Verdugo, N. Ulloa-Chamblás, R. Zúñiga-Tapia et al.
Introduction University students, particularly in health-related fields, face rising levels of stress, anxiety, and depression, which negatively affect academic performance, social engagement, and overall well-being. Post-pandemic challenges, such as social isolation, uncertainty, and abrupt transitions to online learning, have exacerbated these issues. Mindfulness-based interventions (MBIs)...
Test anxiety remains a significant psychological challenge among students in tertiary institutions, often interfering with academic performance, concentration, and emotional well-being. This study examined the effectiveness of a mindfulness-based intervention in reducing test anxiety among undergraduate students. A quasi-experimental pretest–posttest control group design was employed. Eighty...
Introduction Positive feedback from a mental health treatment program that uses treatment adjuncts inspired researchers to assess the potential role of the Apollo Neuro device in mental health outcomes. Objectives To assess the impact of the Apollo Neuro device on anxiety levels in a ketamine-assisted therapy treatment program, comparing those using the device with those not using the device....