TrialsApril 17, 2025Arash Mansoori, Amir Bazrafshan, Jamshid Ahmadi et al.4 citations
The concomitant presence of major depressive disorder (MDD) and opioid use disorder (OUD) poses a formidable clinical challenge, warranting effective interventions that address both psychiatric and addictive components. This study sought to compare the efficacy of adjunctive ketamine and buprenorphine in mitigating anxiety symptom severity and craving intensity in individuals with co-occurring...
Anxiety impacts both physical and mental health, yet it can be alleviated through exercise. This study aimed to investigate the effects of mindfulness-based aerobic dance on policewomen’s anxiety and compare them with those of traditional aerobic dance. A repeated-measures experimental design was employed to assess the effects of mindfulness-based aerobic dance and traditional aerobic dance on...
Background/Objectives: The high prevalence of anxiety and depression in early adolescents, along with the significant disability these conditions, represent a major challenge for mental health. This data underscores the need to understand the variables that predict mental health in this developmental period. Objective: Evaluate the predictive role of mindfulness, difficulties in emotional...
Many kidney transplant recipients continue to be affected by multiple symptoms even after their transplant. Mindfulness may be helpful to alleviate some of the symptoms. Our current study aimed to determine the efficacy of a single session of 20-minute mindful breathing in alleviating multiple symptoms in kidney transplant patients. Adult kidney transplant patients with at least one symptom...
Research SquareApril 16, 2025Jino Park, Rufus Banks, Akul Munjal et al.
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Abstract Background Comorbid mental health symptoms impact 30–40% of cancer patients, significantly compromising treatment adherence and increasing mortality rates. Among patients undergoing radiation therapy, which is delivered with palliative intent in nearly half of all cases and for those nearing end-of-life, these rates may be even higher. Emerging research underscores the promising...
ABSTRACT Our study investigated the effects of guided group meditation sessions on the psychological parameters of depression, stress, anxiety and anger. The present study of 212 participants followed a mixed methods approach. Data was collected using standardized psychological scales and qualitative interview pre- and post-group meditation. Findings revealed a statistically significant...
BMC NeurologyApril 9, 2025Evan Eggiman, William Kerr, Brandon Spivey et al.
Stiff Person Syndrome (SPS) is a rare autoimmune neurological disorder characterized by progressive muscle rigidity and painful spasms. Standard treatments often yield variable responses, particularly in severe, refractory cases. This case report highlights the novel use of ketamine as an effective therapeutic agent for managing acute SPS exacerbations, underscoring its potential as a...
Psilocybin, a naturally occurring psychedelic compound, has garnered renewed scientific interest for its potential in treating psychiatric and neurological disorders. This review systematically examines the latest research on psilocybin’s pharmacokinetics, pharmacodynamics, clinical efficacy, and safety profile. Emerging evidence supports its efficacy in conditions such as major depressive...
Abstract Objectives In-person mindfulness-based interventions (MBIs) have been shown to decrease symptoms of anxiety and stress in autistic adults, who often report high levels of these symptoms. Little is known about the effectiveness of remote MBIs for this population, which may be particularly useful given the common barriers autistic adults face in accessing in-person treatment. This study...
The postpartum period has witnessed increasing rates of depression and anxiety, particularly in the context of the COVID-19 pandemic, with these conditions often co-occurring and being exacerbated by the lingering effects of long COVID. Traditional interventions, such as mindfulness-based stress reduction (MBSR) and yoga, have demonstrated effectiveness in alleviating these symptoms. However,...
Scientific ReportsApril 1, 2025Mahboobeh Soleymani Moghadam, A. Parvizifard, Aliakbar Foroughi et al.
Breast cancer causes numerous physical complications and mental stress that negatively impact patients’ performance and quality of life. This study examined the effects of mindfulness-integrated cognitive behavior therapy (MICBT) on depression, anxiety, stress, and sleep quality in women with breast cancer. A clinical trial design with pre-tests and post-tests and a two-month follow-up were...
Abstract Imagery rehearsal therapy (IRT) is a research-supported behavioral intervention shown to reduce the frequency and severity of nightmares. Research also shows IRT reduces negative mental health symptoms, especially those associated with posttraumatic stress disorder. IRT is straightforward for mental health counselors to facilitate, and the steps for implementing it are described along...
Objective: Up to 40% of adults report poor sleep quality, yet research investigating the role of nightmares on sleep quality is limited. This study aimed to characterise the prevalence of disturbing dreams and nightmares and their relationship to poor sleep quality. Method: 439 adults (310 females, Mage=44.9 years) completed an online survey investigating sleep, dreams, nightmares, and mental...
Abstract Several years ago, the first studies were conducted in which the effects of psychedelics in low doses were tested in healthy participants. These studies focused mainly on the acute effects of LSD. Questions that remained unanswered were whether low doses have lasting effects, as well as whether they can reduce symptoms of ADHD. To answer these questions, we conducted two studies,...
European PsychiatryApril 1, 2025Ilídio Oliveira, A. L. Stephany, M. L. Geremias et al.
Introduction Anxious depression (AxD) as an independent diagnostic has been controversial, with many suggesting it as a transient state and others highlighting evidence of a worse outcome, severity, and increased suicide risk. The International Classification of Diseases (ICD-11) lists a related concept under 6A73, Mixed depressive and anxiety disorder. Previous literature on ketamine’s...
Many individuals who engage in mindfulness experience decreased anxiety. Yet some individuals, particularly those with panic disorder (PD) or elevated anxiety sensitivity (AS), note heightened anxiety when observing particular sensations. The Five Facet Mindfulness Questionnaire (FFMQ) is one of the most widely utilized mindfulness questionnaires. However, its Observe facet has shown...
Rehabilitative measures following spinal cord injury (SCI) typically fail to mitigate the psychological symptoms that might heighten pain levels. Mindfulness-based interventions (MBI) have been proposed to address such concerns. We aim to review the literature on MBI used for pain, anxiety, and depression in SCI. A systematic literature search for studies using MBI in patients with pain and...
Mental disorders, including anxiety and depression, impact nearly 1 billion people worldwide. Recent research has highlighted the potential of certain amphetamine compounds in the therapy of psychiatric disorders, with 3,4-methylenedioxymethamphetamine (MDMA) emerging as a promising candidate. This study investigates the effects of MDMA on anxiety and social behaviours using 3-week-old...
Abstract Background SAPAP3-knockout (SAPAP3-KO) mice develop excessive self-grooming behavior at 4-6 months of age, serving as a model for obsessive-compulsive disorder (OCD). Given that anxiety often precedes OCD diagnosis in humans, this study investigated whether juvenile SAPAP3-KO mice exhibit anxiety-like behaviors before developing the self-grooming phenotype, and whether such behaviors...
This study employed a quantitative research utilizing quasi-experimental approach pre-test and post-test Working on Reducing the Symptoms of Anxiety Enhancing Academic Resilience through the Use of AI-driven Mindfulness and Meditation among College Students. A survey method is used. The sample was composed of (N= 100) college student. Participants used AI-generated Mindfulness and Meditation...