Brain and Behavior
July 1, 2025
Megan Calnan, Grace Blest‐hopley, Chris Busch et al.
4 citations
Abstract Background : Military veterans are at risk of various mental health conditions, with profound implications for post‐deployment quality of life. Current treatment options encounter high dropout rates and non‐responsiveness, and overlook the importance of community building in veterans’ holistic recovery. Preliminary research suggests psychedelics offer therapeutic benefits for...
Psychoneuroendocrinology
July 1, 2025
Ece Idil, Bahar Yuksel, Zeynep Sen et al.
2 citations
Ketamine is a rapid-acting antidepressant with sexually dimorphic effects. Female animals exhibit a higher sensitivity to its antidepressant properties, which has been associated with their ovarian hormone levels. One factor contributing to this sex difference is the faster rate of ketamine metabolism observed in females, potentially regulated by estrogen receptor alpha (ERα) through modulation...
Current Oncology
June 30, 2025
Haley D M Schuman, Chantal Savard, Raèf Mina et al.
9 citations
This systematic review and meta-analysis evaluates (1) the effectiveness of psychedelic-assisted therapy (PAT) using psilocybin and ketamine for psychosocial symptoms in adults with cancer, (2) contextualizes findings with non-randomized and exploratory studies of other psychedelics, and (3) examines the role of therapeutic frameworks in shaping outcomes. We searched PubMed, Cochrane Library,...
JMIR Research Protocols
June 30, 2025
Ravi Shankar, Anjali Bundele, Amartya Mukhopadhyay
8 citations
While traditional mindfulness-based interventions demonstrate effectiveness in improving mental health outcomes, their delivery methods face significant challenges related to accessibility and engagement. Geographic barriers to trained facilitators, time constraints for in-person sessions, and participant dropout rates of 15% to 30% due to perceived monotony limit intervention reach and...
International Journal of Applied Linguistics
June 26, 2025
Mojtaba Khatami, Ferdi Çelik, Raees Calafato et al.
This longitudinal study investigated the dynamic relationship between mindfulness and English‐speaking anxiety among 259 Bangladeshi undergraduates over a semester. Data were collected at three‐monthly intervals using the English Language Speaking Anxiety Scale and the Langer Mindfulness Scale, addressing four research objectives: (1) the cross‐sectional correlation between mindfulness and...
Interest : Jurnal Ilmu Kesehatan
June 26, 2025
Mestiana Br. Karo, Tince Maria Hati Ndruru
Background: Taizé meditation is a form of meditative worship that fosters inner peace through repetitive chants and musical prayers. This practice is particularly beneficial for individuals experiencing anxiety. Anxiety itself is characterized by distressing and uncomfortable emotions that can disrupt a person's sense of equilibrium, manifesting as tension, restlessness, fear, nervousness,...
Clocks & Sleep
June 26, 2025
Y. Tanaka, Yuichiro Otsuka, Suguru Nakajima et al.
1 citation
Worsening adolescent mental health is a significant social issue. Although dreams may reflect one's mental state, few studies have focused on adolescents. Therefore, this study investigated the relationship between dream content and mental health, specifically anxiety disorder and depressive symptoms, among Japanese adolescents. This cross-sectional study obtained data on gender, grade, age,...
Scientific Electronic Archives
June 25, 2025
Maria Zografou, Athanasios Drigas, Alexandros – Stamatios Antoniou
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental condition affecting millions of children globally, characterized by persistent patterns of inattention and/or hyperactivity-impulsivity. Beyond these core symptoms, children with ADHD frequently experience heightened levels of stress and anxiety. These emotional challenges can stem from difficulties in self-regulation,...
June 25, 2025
Mine Doğantan-Dack, László Stachó
Even though anecdotal evidence reveals them as ubiquitous phenomena, the performance anxiety dreams of music performers have not been studied systematically to date in scholarly research. This is all the more surprising given the large research literature on music performance anxiety as a wakeful experience, and the widely accepted “continuity hypothesis” in dream research that asserts...
Biological Psychiatry
June 25, 2025
Kevin G Mulvihill, Gemma J Cockcroft, Angela C Roberts
2 citations
Individual variability in pharmacological treatment efficacy remains a persistent obstacle to ameliorating clinical anxiety. This may originate, in part, from the different neural aetiologies underlying pathological anxiety. To provide novel insights into patient heterogeneity in anxiolytic responsiveness we compare the efficacy of distinct anxiolytic drugs, a Selective Serotonin Re-uptake...
Cureus
June 24, 2025
Alfred Mathew, Roshan Dongre, Seo Hee Kim et al.
The coronavirus variant (causing the COVID-19 disease) that led to a pandemic sent global shockwaves, resulting in long-term effects on physical, mental, and social well-being and impacting both individuals and communities. With the pandemic's notable impact on mental health, one such potential treatment discussed in recent literature is psilocybin. Psilocybin is a naturally occurring prodrug...
Supportive Care in Cancer
June 24, 2025
Ana Ferrigno Guajardo, Misael Salazar-Alejo, Fernanda Mesa-Chavez et al.
3 citations
This study evaluated the efficacy of an online mindfulness-based stress reduction (MBSR) intervention in reducing anxiety among breast cancer (BC) survivors, leveraging the potential advantages of digital delivery to enhance psychosocial care for this population. In this randomized controlled trial, 68 BC survivors with elevated anxiety levels were assigned to either an 8-week online MBSR...
bioRxiv Preprint Server
June 24, 2025
Marco German Ghilotti, Ricardo Petrilli Fortuna, Kofi Osei-Abrefa Ayensu et al.
preprint
Background The use of methamphetamine has continued to rise in the US. In addition to facilitating dopamine neurotransmission, methamphetamine indirectly increases glutamate release which activates N-methyl-D-aspartate receptors (NMDARs). Ketamine is a noncompetitive NMDAR antagonist. Ketamine also has actions on α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) and...
Journal of Psychopharmacology
June 18, 2025
Maria Bălăeţ, William Trender, Annalaura Lerede et al.
2 citations
Mental health implications of COVID-19 drug use patterns are still unclear. We used data-driven clustering in a large citizen science cohort recruited agnostically to an interest in drug-use to categorise people according to common patterns of drug use and analysed their mental health symptoms (GAD-7 and PHQ-9 items), from recruitment prior to COVID-19 restrictions in 2020 (N = 242,260) to...
Journal of Psychoactive Drugs
June 18, 2025
Rafaelle Lancelotta, Meghan DellaCrosse, Diana Quinn et al.
7 citations
This study investigated subjective psychedelic experiences in the global LGBTQIA+ population. Using validated measures of acute psychedelic effects, psychological flexibility, gender and sexual identity attitudes, adverse experiences, and mental health, we examined self-reported changes in identity and mental health outcomes following psychedelic use. A total of 346 individuals completed the...
Journal of Affective Disorders
June 15, 2025
Guangzheng Tang, Bijun Chen, Manhua Wu et al.
Mindfulness-based cognitive therapy (MBCT) has emerged as a promising intervention for generalized anxiety disorder (GAD). This study evaluated MBCT's effectiveness for GAD and examined whether childhood maltreatment moderates its impact. Individuals with GAD were randomized to receive one of two 8-week interventions, either MBCT in-person or psychoeducation on-line (n = 27 per group). At...
British Journal of Pharmacology
June 15, 2025
Daniël Hoyer
9 citations
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N , N ‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g. ibogaine, ketamine and esketamine; and other atypicals e.g. dextromorphan/bupropion, esmethadone....
INDIAN JOURNAL OF MULTIDISCIPLINARY RESEARCH
June 12, 2025
Apu Chakma
This review explores the effectiveness of mantra-based meditation (MBM) in enhancing emotional stability, reducing anxiety and improving quality of life (QoL).Drawing on data from randomized controlled trials (RCTs), meta-analyses and observational studies published in last 1 decade, the review synthesizes findings from diverse populations, including students, veterans, healthcare workers and...
European Journal of Investigation in Health, Psychology and Education
June 12, 2025
Corey Jackson, Christian M Jones
2 citations
This study aimed to address the dearth of literature on mechanisms of effect of mindfulness-based interventions by investigating metacognitive beliefs as a potential mechanism of symptomology-reduction effects. The Cognitive Attentional Syndrome (CAS) component of the Self-Regulatory Executive Function (S-REF) model was augmented to include subtypes of mind wandering and rumination. One hundred...
EDUCATIONE
June 11, 2025
Mohammad Aldi Nuril Asyari, Weni Kurnia Rahmawati, Nailul Fauziyah
Anxiety disorders represent one of the most prevalent mental health challenges globally, with athletes—especially those in high-pressure sports such as pencak silat—facing unique vulnerabilities due to the intense physical, psychological, and cultural demands of competition. This study aimed to evaluate the effectiveness of mindfulness-based interventions in reducing anxiety disorder symptoms...