OUT ON A (PHANTOM) LIMB VARIATIONS ON THE THEME: STABILITY OF BODY IMAGE AND THE GOLDEN SECTION And man created God in his own body image. ROLAND FISCHER* Psychodysleptic Drug-inducedInterference with Readaptation to Distortions It is by now well known that wearing prism spectacles results in a variety ofperceptual distortions which, however, gradually disappear within a period oftime [i, 2,...
30 heavy psychedelic users were compared with 30 matched controls using the Rosenzweig and Comrey tests. The drug-dependent group demonstrated aberrant personality traits only with respect to increased Hostility. It appears that this propensity is unrelated to degree of drug dependency and may reflect a predisposing state. People who have difficulty handling their aggressive feelings may tend...
Contrast effects in an experiment involving no-drug, placebo, and seven drugs were postulated on the basis of Helson's adaptation level theory. For 250 male opiate addicts, it was expected and found that general subjective experiences peculiar to drugs were smaller for no-drug or placebo conditions when these conditions were administered after rather than before potent drugs such as morphine or...
Lysergic acid diethylamide (LSD) and the 5‐hydroxytryptamine (5‐HT) precursor, 5‐hydroxytryptophan produced similar functional effects in rat spinal cord and brain to the 5‐hydroxytryptamine precursor 5‐hydroxytryptophan, which indicates that LSD stimulates central 5‐HT receptors. By means of combined histochemical and biochemical techniques it was found that LSD reduced the turnover rate of...
ScienceSeptember 22, 1967Thomas N. Chase, George R. Breese, Irwin J. Kopin1 citation
Slices of rat brain which had accumulated tritiated serotonin either in vivo or in vitro were superfused and electrically stimulated. There occurred a marked release of the exogenous amine and, to a lesser extent, its deaminated metabolites, which varied with the region of brain tested and was inhibited by lysergic acid diethylamide.
In psychiatric literature, one of the most interesting and complex personality abnormalities is transvestism. We will present a case of a man who is a transvestite, drug addict, alcoholic, and sadomasochist. A multitude of psychiatric papers have been written on the symptomatology and etiology of transvestism, but few on treatment. \N'e will present our observations of the symptomatology,...
SUMMARY: Male Wistar rats were injected s.c. with 500 or 750 μg./kg. of lysergic acid diethylamide (LSD-25) on alternate days for 2 weeks and received a total of eight injections, the last two being on consecutive days. Before autopsy, urinary 17-ketosteroid output, white blood cell counts, body weight, food and oxygen consumption were studied. Depending on time and dosage, the various results...
*Associate Attending, Division of Anesthesiology, Cook County Hospital and Hektoen Institute for Medical Research; Assistant Professor of Medicine and Psychiatry, Chicago Medical School, Chicago, Illinois. †Chairman, Division of Anesthesiology, Cook County Hospital and Hektoen Institute for Medical Research; Associate Professor of Surgery (Anesthesiology), Northwestern University, School of...
This Special Issue of Neuropharmacology on psychedelics provides a timely and comprehensive update on progress following the previous Neuropharmacology Special Issue “ Psychedelics: New Doors, Altered Perceptions ” . Remarkable advances have been made in basic and clinical research on psychedelics in the five years since 2018. It is partly based on the seminar series focused on psilocybin...