Evidence for a central 5‐hydroxytryptamine receptor stimulation by lysergic acid diethylamide
British Journal of Pharmacology September 1, 1968 N.‐e. Andén, H. Corrodi, Kjell Fuxé et al. 274 citations
Lysergic acid diethylamide (LSD) and the 5‐hydroxytryptamine (5‐HT) precursor, 5‐hydroxytryptophan produced similar functional effects in rat spinal cord and brain to the 5‐hydroxytryptamine precursor 5‐hydroxytryptophan, which indicates that LSD stimulates central 5‐HT receptors. By means of combined histochemical and biochemical techniques it was found that LSD reduced the turnover rate of...