Addiction: all studies (page 789) - The Consciousness Library

Ineffability of qualia: a straightforward naturalistic explanation.

Consciousness and Cognition September 1, 2000

Ineffability of qualia: a straightforward naturalistic explanation.

DOI: 10.1006/ccog.2000.0430

A Randomized, Wait-List Controlled Clinical Trial: The Effect of a Mindfulness Meditation-Based Stress Reduction Program on Mood and Symptoms of Stress in Cancer Outpatients

Psychosomatic Medicine September 1, 2000 Michael Speca, Linda E. Carlson, Eileen Goodey et al. 1,091 citations

OBJECTIVE: The objective of this study was to assess the effects of participation in a mindfulness meditation-based stress reduction program on mood disturbance and symptoms of stress in cancer outpatients. METHODS: A randomized, wait-list controlled design was used. A convenience sample of eligible cancer patients enrolled after giving informed consent and were randomly assigned to either an...

DOI: 10.1097/00006842-200009000-00004 Anxiety Meditation Mood Irritability +5

Ibogaine and Noribogaine: Comparing Parent Compound to Metabolite

CNS Drug Reviews September 1, 2000 Carlos Zúbaran 15 citations

ABSTRACT Ibogaine is one of the psychoactive alkaloids found in the West African shrub Tabernanthe iboga. Since the 1980s, a series of US patents have claimed efficacy for ibogaine in the treatment of drug addiction. Since then, more than 60 scientific publications on ibogaine and drug addiction have been published. Ibogaine has an acute and a prolonged effect on neurochemistry and behavior....

DOI: 10.1111/j.1527-3458.2000.tb00149.x Metabolite Neuropharmacology Neurotoxicity Biochemistry

Immunomodulating Activity of MDMA

Annals of the New York Academy of Sciences September 1, 2000 Roberta Pacifici, Piergiorgio Zuccaro, Magı́ Farré et al. 44 citations

Abstract MDMA (3,4‐methylenedioxymethamphetamine) use can cause neurochemical, behavioral and endocrine alterations, similar to those produced by exposure to acute stress, suggesting its potential as a “chemical stressor.” It is known that stressful stimuli can produce a depression of immune function and an alteration in immune cells distribution. In vitro exposure to MDMA resulted in a...

DOI: 10.1111/j.1749-6632.2000.tb05198.x MDMA Immune system Endocrinology Neurochemical +5

Pharmacology of MDMA in Humans

Annals of the New York Academy of Sciences September 1, 2000 Rafael de la Torre, Magı́ Farré, Pere N. Roset et al. 178 citations

Abstract MDMA given at recreational doses (range tested 50 to 150 mg) to healthy volunteers, produced mydriasis and marked increases in systolic and diastolic blood pressure, heart rate, and pupillary diameter. MDMA induced changes on oral temperature. The time course of this observation was biphasic, as a slight decrease at 1 h and a slight increase at 2 and 4 h were observed. MDMA induced a...

DOI: 10.1111/j.1749-6632.2000.tb05199.x MDMA Ecstasy Mydriasis Heart rate +5

Noribogaine (12-hydroxyibogamine): a biologically active metabolite of the antiaddictive drug ibogaine.

Annals of the New York Academy of Sciences September 1, 2000 Michael H. Baumann, John Pablo, S F Ali et al. 37 citations

Ibogaine (IBO) is a plant-derived alkaloid that is being evaluated as a possible medication for substance use disorders. When administered peripherally to monkeys and humans, IBO is rapidly converted to an o-demethylated metabolite, 12-hydroxyibogamine (NORIBO). We have found in rats that peak blood levels of NORIBO can exceed those of the parent compound, and NORIBO persists in the bloodstream...

DOI: 10.1111/j.1749-6632.2000.tb05210.x Full text Noribogaine Ibogaine metabolite Anti-addiction drug metabolite Addiction treatment +5

Application of electrophysiological method to study interactions between ibogaine and cocaine.

Annals of the New York Academy of Sciences September 1, 2000 Zbigniew Binienda, Michael A Beaudoin, Brett T Thorn et al. 4 citations

The psychoactive indole alkaloid, ibogaine (IBO), has been investigated for over a decade concerning its reported anti-addictive properties for opioids as well as psychomotor stimulants. The mechanism for the anti-addictive action of IBO is still unclear. IBO interactions with opioid, NMDA, nicotinic, adrenergic, and serotonergic receptor sites have been suggested. The involvement of the...

DOI: 10.1111/j.1749-6632.2000.tb05212.x Full text Ibogaine pretreatment Alter brain's reaction Dampens response Cocaine-induced +7

Ibogaine: complex pharmacokinetics, concerns for safety, and preliminary efficacy measures.

Annals of the New York Academy of Sciences September 1, 2000 Deborah C. Mash, Craig A. Kovera, John Pablo et al. 146 citations

Ibogaine is an indole alkaloid found in the roots of Tabernanthe Iboga (Apocynaceae family), a rain forest shrub that is native to western Africa. Ibogaine is used by indigenous peoples in low doses to combat fatigue, hunger and thirst, and in higher doses as a sacrament in religious rituals. Members of American and European addict self-help groups have claimed that ibogaine promotes long-term...

DOI: 10.1111/j.1749-6632.2000.tb05213.x Full text Noribogaine Substance abuse treatment Addiction treatment Drug rehabilitation +16

Binding of beta-carbolines and related agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors.

Drug and Alcohol Dependence August 1, 2000 Richard A Glennon, M Dukat, B Grella et al.

A large series of beta-carbolines was examined for their ability to bind at [3H]agonist-labeled 5-HT(2A) serotonin receptors. Selected beta-carbolines were also examined at 5-HT(2C) serotonin receptors, 5-HT(1A) serotonin receptors, dopamine D(2) receptors, and benzodiazepine receptors. Indolealkylamines and phenylisopropylamines were also evaluated in some of these binding assays. The...

DOI: 10.1016/s0376-8716(99)00148-9 Full text

Piaget and Levy-Bruhl.

History of psychology August 1, 2000 G Jahoda

Levy-Bruhl exerted a powerful influence, seldom considered, on Piaget. The Levy-Bruhlian thesis of a "pre-logical mentality" characterized by "mystical participation" is outlined, together with its initial reception. The first evidence of Piaget's interest in it dates from 1920, and when he began his studies of children's thinking he compared it with that of 'primitives," also adopting...

DOI: 10.1037/1093-4510.3.3.218 Full text

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