The consumption of cannabinoids has increased exponentially in the young. The cannabis-induced psychotic disorder is a rare condition, with transient paranoid ideation being the most common manifestation. Symptoms of anxiety are the most common adverse reaction associated with the moderate use of smoked cannabis. Cocaine use, in turn, is related to the appearance of delusions and hallucinations...
New title, or subtitle: „Current knowledge on the neurobiology of classical hallucinogens and their relevance for the treatment of mood and anxiety disorders‘ Hallucinogenic substances have been used for millenia. Still, the scientific investigation into the effects and mechanisms of classical hallucinogens in humans has only commenced with the discovery of LSD by Albert Hofmann in 1943. In the...
Human Brain MappingMarch 2015Carinna M Torgerson, Andrei Irimia, S Y Matthew Goh et al.
The origin, structure, and function of the claustrum, as well as its role in neural computation, have remained a mystery since its discovery in the 17th century. Assessing the in vivo connectivity of the claustrum may bring forth useful insights with relevance to model the overall functionality of the claustrum itself. Using structural and diffusion tensor neuroimaging in N = 100 healthy...
Turk pediatri arsiviMarch 2015Sezen Ugan Atik, Reyhan Dedeoğlu, Fatih Varol et al.
Information about the effects of synthetic cannabinoids "bonzai" on the cardiovascular system is limited. In this article, two patients in whom different cardiological side effects were observed following use of synthetic cannabinoids 'bonzai' were presented. Our first patient who was a 16-year old boy presented to pediatric emergency department with severe chest pain which had started one hour...
European PsychiatryMarch 1, 2015A. Ghaffarinejad, H. Ziaadini, Siamak Zadeh et al.1 citation
Background Psychotic disorder due to industrial drug, such as methamphetamine addiction, is one of the important causes for referral to psychiatric hospital. Psychotic symptoms in these patients are varied. A group of researchers believe that methamphetamine-induced psychosis is completely similar to schizophrenia. Others believe that at least some cases of permanent psychotic clinical...
In this study we sought to explore patterns of neural activity related to the self/other-agency judgment in patients with first-episode schizophrenia spectrum disorders (FES) and healthy controls (HC). Thirty-five FES patients and 35 age-, gender- and education-matched healthy controls. A task-related functional connectivity analysis with the use of independent component analysis (ICA). ICA...
March 1, 2015Aleksandra Piątek, Małgorzata Koziarska-Rościszewska, J. Zawilska
Abstract Recreational substance use is becoming more common, especially among young people. Some anti-inflammatory or antitussive drugs exert potent psychoactive effects when they are used in large doses. Easily available over-the-counter (OTC) drugs may cause a range of effects including hallucinations or euphoria. Dextromethorphan (DXM) is particularly often used. At doses of 1.5–7.5 mg/kg...
In the early 1900s, the Dream of the Rarebit Fiend comic strip conveyed how the spicy cheese dish Welsh rarebit leads to bizarre and disturbing dreams. Today, the perception that foods disturb dreaming persists. But apart from case studies, some exploratory surveys, and a few lab studies on how hunger affects dreaming, there is little empirical evidence addressing this topic. The present study...
Interest in the therapeutic potential of psychedelic substances has recently resumed. During an early phase of human psychedelic research, their therapeutic application in different pathologies had been suggested, and the first evidence for efficacy was provided. The range of recent clinical applications of psychedelics spans from cluster headaches and obsessive-compulsive disorder to addiction...
For more than 40 years following its approval by the Food and Drug Administration (FDA) as an anesthetic, ketamine, a non-competitive N-methyl-d-aspartic acid (NMDA) receptor antagonist, has been used as a tool of psychiatric research. As a psychedelic drug, ketamine induces psychotic symptoms, cognitive impairment, and mood elevation, which resemble some symptoms of schizophrenia. Recreational...