International Journal of Social Psychiatry
November 1, 2014
Betty E Koka, Frank P Deane, Geoffrey Cb Lyons et al.
5 citations
Papua New Guinea is a developing country with limited resources for specialist mental health services. Little is known about the mental health and treatment services of Papua New Guinea. The aim of this study was to clarify the presenting mental health problems encountered by Papua New Guinean health workers and the common treatment approaches used. A total of 203 Papua New Guinean health...
The International Journal of Neuropsychopharmacology
October 31, 2014
Ashley E. Lepack, Manabu Fuchikami, J. M. Dwyer et al.
369 citations
BACKGROUND: Recent studies demonstrate that the rapid antidepressant ketamine increases spine number and function in the medial prefrontal cortex (mPFC), and that these effects are dependent on activation of glutamate α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and brain-derived neurotrophic factor (BDNF). In vitro studies also show that activation of AMPA receptors...
Temperature
October 31, 2014
Matthias E. Liechti
64 citations
Hyperthermia is a severe complication associated with the recreational use of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy). In this review, the clinical laboratory studies that tested the effects of MDMA on body temperature are summarized. The mechanisms that underlie the hyperthermic effects of MDMA in humans and treatment of severe hyperthermia are presented. The data show that MDMA...
Frontiers in Psychology
October 30, 2014
Philipp Ruhnau, Anne Hauswald, Nathan Weisz
In cognitive neuroscience, prerequisites of consciousness are of high interest. Within recent years it has become more commonly understood that ongoing brain activity, mainly measured with electrophysiology, can predict whether an upcoming stimulus is consciously perceived. One approach to investigate the relationship between ongoing brain activity and conscious perception is to conduct...
Journal of Psychoactive Drugs
October 20, 2014
James A. Wilcox
55 citations
Obsessive Compulsive Disorder (OCD) is a psychiatric disorder with considerable morbidity and mortality. This condition disables many individuals and is often refractory to treatment. Research suggests that serotonin plays a role in OCD symptom reduction. We present a case of an individual who successfully used psilocybin, a serotonergic agent, to reduce the core symptoms of OCD for several...
Frontiers in Psychology
October 9, 2014
J Allan Hobson, Charles C-H Hong, Karl Friston
This article explores the notion that the brain is genetically endowed with an innate virtual reality generator that - through experience-dependent plasticity - becomes a generative or predictive model of the world. This model, which is most clearly revealed in rapid eye movement (REM) sleep dreaming, may provide the theater for conscious experience. Functional neuroimaging evidence for brain...
Journal of Clinical Psychopharmacology
October 2014
Colin Cameron, Diane Watson, Jeffrey D. Robinson
Nabilone is a synthetic cannabinoid that has shown promise for the treatment of posttraumatic stress disorder (PTSD)-related insomnia and nightmares as well as efficacy in the management of chronic pain. It has also been proposed for harm reduction in cannabis dependence. Its effectiveness for management of concurrent disorders in seriously mentally ill correctional populations has not been...
Archives of Psychiatric Nursing
October 2014
Navidreza Hosseinzadeh Asl, Usha Barahmand
The present study aimed at examining the effect of Mindfulness-Based Cognitive Therapy (MBCT) in decreasing depression symptoms in dully diagnosed males (drug dependent males with co-morbid depression).An experimental research design with pre- and post-tests and a control group was used. The sample of the study comprised 33 drug-dependent men who also endorsed depression symptoms on the Beck...
Neuroscience
September 26, 2014
F Tirgar, A Rezayof, M-R Zarrindast
The present study was designed to investigate possible involvement of the central amygdala (CeA) nicotinic acetylcholine (nACh) and 5-hydroxytryptamine 1A (5-HT1A) receptors in the reversal effect of nicotine and 3,4-methylenedioxy-N-methylamphetamine (MDMA or ecstasy) on morphine-induced amnesia. Two guide cannulas were stereotaxically implanted in the CeA regions and a step-through passive...
Frontiers in Human Neuroscience
September 22, 2014
Francesca eFiori, Nicole eDavid, Salvatore Maria Aglioti
In the rod and frame test (RFT), participants are asked to set a tilted visual linear marker (i.e. a rod), embedded in a square, to the subjective vertical, irrespective of the surrounding frame. People not influenced by the frame tilt are defined as field-independent, while people biased in their rod verticality perception are field-dependent. Performing RFT requires the integration of...