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Addiction: all studies

Page 579 of 859: studies 5,781 to 5,790 of 8,590, newest first. Back to the addiction overview

Research

Prácticas en búsqueda de legitimidad: el uso contemporáneo de la ayahuasca, entre reivindicaciones terapéuticas y religiosas

Salud Colectiva July 24, 2018 David Dupuis 17 citations

El creciente interés de los occidentales por la bebida psicotrópica ayahuasca y la participacion en rituales exóticos ha llevado en las últimas décadas a la multiplicación de los “centros chamánicos” en la Amazonía peruana. Entre estos, el centro Takiwasi es una comunidad terapéutica que acoge cada año a cientos de clientes nacionales y extranjeros. Esta institución, creada por un médico...

Extended Mind and the Authority of Consciousness

July 20, 2018 Adam Green

The extended mind thesis holds that the mental is not restricted to what ­happens in the brain. Rather, one can think of the extended mind thesis as an outgrowth of broader, physicalist commitments. In particular, views of the mental that tie it very strongly to consciousness seem to be in a position to resist the extension of mind. One way of taking the origin and force of the extended mind...

Cytochrome P450 and O-methyltransferase catalyze the final steps in the biosynthesis of the anti-addictive alkaloid ibogaine from Tabernanthe iboga

Journal of Biological Chemistry July 20, 2018 Scott C. Farrow, Mohamed O. Kamileen, Jessica Meades et al. 55 citations

Monoterpenoid indole alkaloids are a large (∼3000 members) and structurally diverse class of metabolites restricted to a limited number of plant families in the order Gentianales. Tabernanthe iboga or iboga (Apocynaceae) is native to western equatorial Africa and has been used in traditional medicine for centuries. Howard Lotsof is credited with bringing iboga to the attention of Western...

DOI: 10.1074/jbc.ra118.004060 (opens in new tab) Full text (opens in new tab) Indole alkaloid Apocynaceae Pharmacology Biochemistry +4

Role of AMPA glutamate receptors in the conditioned rewarding effects of MDMA in mice.

Behavioural Brain Research July 16, 2018 María P García-Pardo, José Miñarro, María A. Aguilar

Currently, there is not an effective treatment for 3,4-methylenedioxymethamphetamine (MDMA) dependence but pharmacotherapies targeting glutamate neurotransmission are a promising strategy. Previously, we showed that blockade of glutamate NMDA and AMPA receptors impairs the conditioned rewarding effects of MDMA and cocaine, respectively. In this study we evaluated the role of AMPA receptors in...

DOI: 10.1016/j.bbr.2018.03.010 (opens in new tab) Full text (opens in new tab) MDMA Ampa receptors Cnqx Conditioned place preference +2

Evaluation of reinforcing and aversive effects of voluntary Δ9-tetrahydrocannabinol ingestion in rats.

Neuropharmacology July 15, 2018 Daniel G Barrus, Timothy W Lefever, Jenny L Wiley

Edible cannabis-infused products are an increasingly popular method of using cannabis in the United States. Yet, preclinical research to determine mechanisms underlying abuse of Δ9-tetrahydrocannabinol (THC), the primary psychoactive constituent of cannabis, has focused primarily on the effects of parenteral administration. The purpose of this study was to examine the rewarding and aversive...

DOI: 10.1016/j.neuropharm.2018.04.018 (opens in new tab) Full text (opens in new tab) Cannabinoid Delta-9-tetrahydrocannabinol Oral Self-administration +1

Does the association between mindful parenting and adolescents' dispositional mindfulness depend on the levels of anxiety and depression symptomatology in mothers?

Journal des adolescens July 13, 2018 Helena Moreira, Maria C Canavarro

The current study aims to investigate whether mindful parenting and adolescents' dispositional mindfulness differ as a function of maternal anxiety and depressive symptoms and to explore the moderating role of these symptoms on the relationship between mindful parenting and adolescents' dispositional mindfulness. A sample of 685 mother-adolescent dyads was collected in Portuguese public...

Web-based intervention to improve quality of life in late stage bipolar disorder (ORBIT): randomised controlled trial protocol

BMC Psychiatry July 12, 2018 Kathryn Fletcher, Fiona Foley, Neil Thomas et al. 39 citations

BACKGROUND: The primary objective of this randomised controlled trial (RCT) is to establish the effectiveness of a novel online quality of life (QoL) intervention tailored for people with late stage (≥ 10 episodes) bipolar disorder (BD) compared with psychoeducation. Relative to early stage individuals, this late stage group may not benefit as much from existing psychosocial treatments. The...

The Conscious Brain

Forum Philosophicum July 11, 2018 Józef Bremer, Dariusz Adamek

The goal of this article is to review some aspects of brain anatomy and neurophysiology that are important for consciousness, and which hopefully may be of benefit to philosophers investigating the conscious mind. Taking as an initial point of reference the distinction between “the hard problem” and “the weak problems” of consciousness, we shall concentrate on questions pertaining to the second...

Phenomenology and German Idealism

Oxford Handbooks Online July 10, 2018 Alexander Schnell

The thesis of this chapter consists in putting forward the idea that, from the point of view of their speculative foundation, the works of the founding fathers of phenomenology (Husserl and Heidegger) admit of a unity, the nature of which is clarified by certain crucial contributions from German idealism. The perspective that the author is concerned to develop consists in attempting to show...

Bonsai intoxication at emergency service: A review of 61 cases

Journal of Surgery and Medicine July 10, 2018 Nadiye Karabulut, Ayşe Seda Demirel Dengi, Sündüs Görükmez et al. 1 citation

Aim: The aim of this study was to determine the effects of bonzai by assessing the correlation between the clinical and laboratory findings of cases diagnosed with bonsai intoxication who had been monitored in the emergency service.Methods: This study was approved by ‘’Haseki Training and Research Hospital Ethical Committee of Non-Pharmacological Studies’’ with approval number of:183 on...