Human Psychopharmacology: Clinical and Experimental
February 17, 2022
Edward James, Joachim Keppler, Ben Sessa et al.
41 citations
Abstract Objective Reports have indicated possible uses of ayahuasca for the treatment of conditions including depression, addictions, post‐traumatic stress disorder, anxiety and specific psychoneuroendocrine immune system pathologies. The article assesses potential ayahuasca and N,N‐dimethyltryptamine (DMT) integration with contemporary healthcare. The review also seeks to provide a summary of...
Frontiers in Human Neuroscience
February 16, 2022
Asa Young, Tam Hunt, Marissa Ericson
34 citations
Electromagnetic field oscillations produced by the brain are increasingly being viewed as causal drivers of consciousness. Recent research has highlighted the importance of the body’s various endogenous rhythms in organizing these brain-generated fields through various types of entrainment. We expand this approach by examining evidence of extracerebral shared oscillations between the brain and...
Behavioural Brain Research
February 15, 2022
Vassiliy Tsytsarev
There are at least two approaches to the definition of consciousness. In the first case, certain aspects of consciousness, called qualia, are considered inaccessible for research from a third person and can only be described through subjective experience. This approach is inextricably linked with the so-called "hard problem of consciousness", that is, the question of why consciousness has...
bioRxiv Preprint Server
February 14, 2022
Tudor M. Ionescu, Mario Amend, Tadashi Watabe et al.
1 citation
preprint
Psychedelic compounds have attracted increasing interest in recent years due to their therapeutic potential for psychiatric disorders. Methylenedioxymethamphetamine (MDMA) is currently being investigated in clinical trials to treat post-traumatic stress disorder. To understand the acute effects of psychedelic drugs in vivo, functional MR imaging (fMRI) has been widely used in recent years....
Journal of Neurochemistry
February 12, 2022
Johannes T. Reckweg, Malin V. Uthaug, Attila Szabo et al.
108 citations
Abstract 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) is a naturally occurring tryptamine that primarily acts as an agonist at the 5‐HT1A and 5‐HT2A receptors, whereby affinity for the 5‐HT1A subtype is highest. Subjective effects following 5‐MeO‐DMT administration include distortions in auditory and time perception, amplification of emotional states, and feelings of ego dissolution that...
The Brown University Child & Adolescent Psychopharmacology Update
February 10, 2022
Alison Knopf
The January issue of the American Journal of Psychiatry (AJP) focuses on the interactions between alcohol use, cannabis use, substance use disorders (SUDs), and other psychiatric illnesses. One of the biggest questions for clinicians treating patients with first‐episode psychosis when cannabis has been involved is the chicken‐and‐egg question — was the psychosis brought on by cannabis use or...
In Consciousness we Trust
February 10, 2022
Hakwan Lau
Abstract: This book will focus on subjective experience, also known as phenomenal consciousness. But this may also relate to other notions of consciousness such as wakefulness and volitional control (contra automaticity). An important distinction has been made between subjective experience and informational access. However, just because two concepts are distinct does not mean that they are...
Middle East Current Psychiatry
February 10, 2022
El Hassan Ouanouche, Hicham Elmostafi, Naoufal Amarat et al.
In addition to the biological plausibility widely described through a very large number of studies, the causal link between cannabis uses and schizophrenia disorders has become illicit internationally and given the scarcity of similar studies in Morocco. Our study consists of a prospective descriptive study in the psychiatric department of the Moulay ben Abdallah Hospital in Essaouira. The...
Frontiers in Aging Neuroscience
February 10, 2022
K. Watson, Angela D Bryan, R. Thayer et al.
Several lines of evidence suggest that older adults (aged 65+) sharply increased their cannabis use over the last decade, highlighting a need to understand the effects of cannabis in this age group. Pre-clinical models suggest that cannabinoids affect the brain and cognition in an age-dependent fashion, having generally beneficial effects on older animals and deleterious effects on younger...
Current Biology
February 7, 2022
Daniel Gutierrez-Barragan, Neha Atulkumar Singh, Filomena Grazia Alvino et al.
Human imaging studies have shown that spontaneous brain activity exhibits stereotypic spatiotemporal reorganization in awake, conscious conditions with respect to minimally conscious states. However, whether and how this phenomenon can be generalized to lower mammalian species remains unclear. Leveraging a robust protocol for resting-state fMRI (rsfMRI) mapping in non-anesthetized, head-fixed...