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Addiction: all studies

Page 3 of 857: studies 21 to 30 of 8,563, newest first. Back to the addiction overview

Research

Novel pharmacotherapies for opioid use disorder and opioid withdrawal

Frontiers in Psychiatry September 3, 2026 Mary R. Shen, Kwadwo Owusu-Boaitey, Zackari D. Murphy et al.

IntroductionOpioid use disorder (OUD) remains a major public health crisis despite evidence-based medications, including methadone, buprenorphine, and naltrexone. Persistent challenges with treatment retention, access, stigma, and incomplete response highlight the need for adjunctive pharmacotherapies targeting neurobiological systems beyond the mu-opioid receptor.MethodsWe conducted a...

Through the Looking-Glass: A Scoping Review of Psychological Mechanisms of Psychedelic-Assisted Therapy for Substance Use Disorders

Current Addiction Reports September 2, 2026 Kathryn Fletcher, Jack Freestone, Nadine Ezard et al.

Abstract Purpose of Review Psychedelic-assisted therapy (PAT) has re-emerged as a potential intervention for substance use disorders (SUDs), yet the psychological mechanisms underlying behaviour change remain poorly synthesised. This scoping review mapped and evaluated proposed psychological processes underpinning PAT in adults with SUDs. Recent Findings Peer-reviewed English-language empirical...

Practice, dependence, and transcendence in the Bhagavad Gītā, Yoga-Sūtra, and liberation mathematics

International Journal of Sanskrit Research September 1, 2026 Authors Names Swapan Samanta

Every contemplative discipline begins because something in the practitioner requires cultivation. This paper asks what becomes of the practitioner's dependence on the cultivating instrument once cultivation succeeds. It proposes the Ceiling Theorem: a pathway of practice becomes a ceiling when the integration it has helped to cultivate grows increasingly contingent on the preservation of that...

Tolerance, physical dependence, and Δ9-THC-like interoceptive effects of cannabinol in mice.

Drug and Alcohol Dependence September 1, 2026 S. Vanegas, J. Marusich, J. Maturano et al.

BACKGROUND AND PURPOSE Cannabinoids, including Δ9-tetrahydrocannabinol (THC) and synthetic CB1 agonists elicit acute psychotropic effects that undergo tolerance with repeated exposure. In contrast, the effects of prolonged cannabinol (CBN) use are unknown. This study examined (1) the effects of repeated CBN administration on classic cannabimimetic outcomes, (2) whether these effects undergo...

Smartphone-Delivered MBRP and Quality of Life among Individuals With Opioid Use Disorder: A Pilot Before-After Study.

Health science reports September 2026 Shadi Dashtbani, Hadi Ramesh, Narges Norouzkhani et al.

Mindfulness-Based Relapse Prevention (MBRP) combines mindfulness practice with relapse-prevention strategies and has demonstrated efficacy in improving psychological well-being among individuals with substance use disorders. This pilot study evaluated quality-of-life changes following an audio-based mobile MBRP application delivered as an adjunct to methadone maintenance treatment (MMT) among...

DOI: 10.1002/hsr2.73103 (opens in new tab) Full text (opens in new tab) Opioid use disorder Methadone maintenance treatment Mindfulness‐based relapse prevention Mobile health +2

Digital game addiction, mindfulness, and phubbing among adolescents: a cross-sectional design.

European Journal of Pediatrics August 31, 2026 Neslihan Köse-Kabakcıoğlu, Sultan Ayaz-Alkaya

This study was conducted to identify factors associated with phubbing and to investigate the mediating role of mindfulness in the relationship between digital game addiction and phubbing. A cross-sectional design with mediation analysis was adopted. The study was completed with 2013 voluntary adolescents. The data were collected via paper questionnaires that included validated Turkish versions...

Psilocybin-Assisted Therapy for Alcohol Use Disorder: A Systematic Review of Clinical Evidence

Psychoactives August 30, 2026 Laura Schäffert, Human-Friedrich Unterrainer

Background: Alcohol use disorder (AUD) remains a leading contributor to global morbidity, yet conventional treatments often yield suboptimal outcomes and high relapse rates. Psilocybin-assisted therapy has re-emerged as a potential intervention for substance use disorders, but its effectiveness and safety in AUD specifically remain to be comprehensively evaluated. Objective: To review and...

Effectiveness of Laughter Yoga and Mindfulness on Psychological Well-Being and Physiological Parameters among School-Going Adolescents at Risk for Smartphone Addiction: A Quasi-Experimental Study

Journal of Health and Allied Sciences NU August 21, 2026 Bright A P Sr Deepa Peter, Priya Reshma Aranha, A P Krishna

Objectives Smartphone addiction among adolescents is an emerging public health concern affecting psychological well-being and physiological health. Limited research studies exist on integrated, low-cost, school-based interventions addressing both domains. This study helps to evaluate the effectiveness of laughter yoga and mindfulness on psychological well-being and physiological parameters...

Psilocybin-assisted psychotherapy for substance use disorders as a complex intervention: A systematic review of efficacy, mechanisms and psychotherapeutic frameworks

Journal of Psychopharmacology August 17, 2026 Lana Strika-Bruneau, Chérine Elhssaini, Baptiste Fauvel et al.

Background: Psychedelic-assisted psychotherapy (PAP) shows promise for substance use disorders (SUDs), yet the respective contributions of pharmacological, experiential, psychotherapeutic, and contextual factors remain insufficiently understood. Objective: To synthesize contemporary clinical evidence on PAP for SUDs, with particular attention to therapeutic frameworks, dosing strategies,...

The Principle of Structural Dependence: An Organisational Constraint for Models of Awareness

Zenodo (CERN European Organization for Nuclear Research) August 16, 2026 Alison Jane King, Darryl Gray preprint

This manuscript develops the Principle of Structural Dependence (PSD) as a general organisational constraint for theories and empirical models of awareness and cognitive capacities. PSD proposes that measurable differences in a capacity require corresponding differences in the organisation relevant to supporting that capacity. The principle is deliberately modest: it does not specify what...