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Addiction: all studies

Page 142 of 857: studies 1,411 to 1,420 of 8,563, newest first. Back to the addiction overview

Research

A testable theoretical framework linking cranial osteopathic still-point induction to altered consciousness via convergent autonomic, default-mode, and interoceptive mechanisms.

Explore August 23, 2026 Siddhant Nikam, Nimisha S Narayan

Patients undergoing Still Point induction via compression of the fourth ventricle (CV4) in cranial osteopathy commonly report a distinctive quality of profound mental quiet, described as qualitatively different from ordinary relaxation. Cranial osteopathy, however, entered a prolonged crisis of scientific credibility once controlled work indicated that its founding construct, the Primary...

The Prospective Structure of Qualia: Transition Fields, Anchoring, and Configuration Mismatch

Zenodo (CERN European Organization for Nuclear Research) August 23, 2026 Francis Smith preprint

This preprint develops a state-space account of phenomenal character in which conscious experience depends not only on the configuration presently realized, but also on the represented structure of transitions available from that configuration. The framework distinguishes current phenomenal configuration, external anchoring, and a prospective transition field describing the topology of...

Perceptions of Psychedelic Decriminalization: Findings from a Community Survey of People Who Use Psychedelics

Social Sciences August 23, 2026 Daniel J. Kruger, Julie Barron, Larry Norris

Psychedelic decriminalization has moved from the margins of drug-policy discourse to a mainstream public health and equity conversation. This community survey reveals that people with psychedelic experience who live in areas that have decriminalized psychedelics report greater benefits of psychedelic decriminalization than adverse outcomes. In decriminalized zones, most (84.0%) participants (N...

From Extended Minds to Coupling Flexibility: Cognitive Eco-Sourcing and Generative AI in Education

PsyArXiv August 22, 2026 Laura Desirée Di Paolo preprint

Debates about generative artificial intelligence (AI) in education often oppose enhancement to diminishment. This framing obscures important differences in how learners recruit AI and how cognitive labour is distributed between agents and technological resources. We introduce cognitive eco-sourcing as a framework for analysing these relations. It distinguishes four non-parallel and potentially...

The effects of a mobile health application on adolescent mental health during the COVID-19 pandemic: a randomized controlled study

Scientific Reports August 22, 2026 Won Ju Hwang, Hwiyun Kim, Hyojin Kim

Adolescents experienced substantial psychological distress during the COVID-19 pandemic, including elevated stress, disrupted routines, reduced peer interaction, and reduced access to in-person professional support. Mobile health (mHealth) interventions may offer accessible and scalable support for adolescents when conventional services are disrupted. This preliminary randomized controlled...

MDMA-Assisted Therapy for Neuropathic Pain: Mechanisms, Evidence, and the Case for Dedicated Clinical Trials: A Narrative Review

Zenodo (CERN European Organization for Nuclear Research) August 21, 2026 Ivan Temprado-Ordiaz preprint

3,4-Methylenedioxymethamphetamine (MDMA) has emerged as a promising therapeutic candidate for treatment-resistant neuropathic pain, offering a paradigm shift from transient palliative symptom masking toward disease-modifying neuroplastic reorganization. Preclinical and clinical evidence demonstrates that MDMA operates through an integrated, multi-tiered neurobiological cascade: presynaptic...

Exploring Psychedelics as Novel Therapeutics for Smoking Cessation: Mechanistic Insights from Animal Studies

VCU Scholars Compass August 21, 2026 Belle Buzzi

Tobacco use remains a leading cause of preventable morbidity and mortality worldwide, and current smoking cessation treatments are limited by low long-term efficacy. An interplay between positive and negative reinforcement drives high relapse rates. Psychedelic compounds, particularly psilocybin, have shown promising clinical outcomes for smoking cessation, yet the neurobiological and...

Bibliometric analysis of meditation as interventions for mental and behavioral disorders: performance, intellectual structure, and thematic evolution (2000–2024)

August 21, 2026 Amit Kumar Soni preprint

Bibliometric Analysis of Meditation-Based Interventions for Mental and Behavioral Disorders: Performance, Intellectual Structure, and Thematic Evolution (2000–2024) Objectives This study will conduct a comprehensive bibliometric analysis of meditation-based interventions for mental and behavioral disorders published between 2000 and 2024. It will examine publication and citation performance,...

The Drive of Consciousness Is Not in the Brain: A Theoretical Statement on the Bodily Origins of Seeking-to-Connect

Zenodo (CERN European Organization for Nuclear Research) August 21, 2026 preprint

意识的驱动力并不在大脑中:关于‘寻求联结’之身体起源的理论阐述;This theoretical statement proposes an alternative entry point for consciousness research: the drive of consciousness originates in the body, not in the brain. The dominant brain-centric route — the search for neural correlates of consciousness (NCC) — has not converged after three decades and leaves one underlying question unanswered: why should the brain...

Side-Chain Homologs of Δ9-THC, Δ8-THC, and HHC Reveal Pathway Bias at CB1R and CB2R Cannabinoid Receptors.

Molecular Neurobiology August 20, 2026 Oleh Durydivka, Ondřej Florián, Petr Palivec et al.

Minor cannabinoids and semisynthetic cannabis constituents, such as derivatives of tetrahydrocannabinol (THC) and hexahydrocannabinol (HHC), are increasingly encountered in consumer products, yet their signaling profiles at cannabinoid receptors remain incompletely characterized. Here, we describe how structural modifications of THC and HHC, including variations in alkyl side-chain length...

DOI: 10.1007/s12035-026-06145-8 (opens in new tab) Full text (opens in new tab) Tetrahydrocannabinol Arrestins Cannabinoid receptors G protein-coupled receptors +2