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Addiction research published in 2011

21 studies whose primary subject is addiction were published in 2011, up from 12 in 2010. Newest first. Back to the addiction overview

Studies

Mindful attention reduces neural and self-reported cue-induced craving in smokers

Social Cognitive and Affective Neuroscience November 22, 2011 Cecilia Westbrook, J. David Creswell, Golnaz Tabibnia et al. 278 citations

An emerging body of research suggests that mindfulness-based interventions may be beneficial for smoking cessation and the treatment of other addictive disorders. One way that mindfulness may facilitate smoking cessation is through the reduction of craving to smoking cues. The present work considers whether mindful attention can reduce self-reported and neural markers of cue-induced craving in...

Doctor is suspended for prescribing a drug for pornography "addiction" without giving the risks

BMJ October 17, 2011 C. Dyer 2 citations

A doctor in private practice has been suspended for six months by the General Medical Council for giving the unlicensed hallucinogenic drug ibogaine to a man obsessed with internet pornography without fully explaining the drug’s risks. Peter Brackenridge, who saw private patients in London’s Harley Street, was medical director of Ibogaine Therapy UK, which advertised the treatment on a website....

Using Meditation in Addiction Counseling

Journal of Addictions & Offender Counseling October 1, 2011 Mark E. Young, Leigh DeLorenzi, Laura Cunningham 16 citations

Meditation has been studied as a way of reducing stress in counseling clients since the 1960s. Alcoholics Anonymous, Narcotics Anonymous, and new wave behavior therapies incorporate meditation techniques in their programs. This article identifies meditation's curative factors and limitations when using meditation in addiction settings.

The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias

BMC Pharmacology September 5, 2011 Michael Kovar, Xaver Koenig, Ágnes K. Mike et al. 5 citations

Background Ibogaine is an alkaloid derived from the African shrub Tabernanthe iboga. Psychoactive properties of ibogaine have been known for decades, but more recently the drug has received much attention because of its promising “anti-addictive” actions. Thus, ibogaine and its derivatives are being studied as potential treatment for opioid and stimulant abuse, as well as for alcoholism and...

DOI: 10.1186/1471-2210-11-s2-a1 (opens in new tab) Addiction Stimulant Pharmacology Qt interval +7

Drug addiction, love, and the higher power.

Evaluation & the health professions September 2011 Steve Y Sussman, Michel Reynaud, Henri-Jean Aubin et al.

This discussion piece suggests that reliance on a Higher Power in drug abuse recovery programs is entertained among some addicts for its psychobiological effects. Prayer, meditation, early romantic love, and drug abuse may have in common activation of mesolimbic dopaminergic pathways of the brain and the generation of intense emotional states. In this sense, reliance on a Higher Power may...

Ketamine use: a review

Addiction July 21, 2011 Celia J. A. Morgan, Helen Valerie Curran 645 citations

AIMS: Ketamine remains an important medicine in both specialist anaesthesia and aspects of pain management. At the same time, its use as a recreational drug has spread in many parts of the world during the past few years. There are now increasing concerns about the harmful physical and psychological consequences of repeated misuse of this drug. The aim of this review was to survey and integrate...

Dronabinol for the treatment of cannabis dependence: a randomized, double-blind, placebo-controlled trial.

Drug and Alcohol Dependence July 1, 2011 Frances R. Levin, John J Mariani, Daniel J Brooks et al.

Cannabis dependence is a substantial public health problem. Behavioral treatments have shown promise, but there are no effective medications for cannabis dependence. The purpose of this study was to evaluate the safety and efficacy of dronabinol, a synthetic form of delta-9-tetrahydrocannabinol, a naturally occurring pharmacologically active component of marijuana, in treating cannabis...

Emergent pharmacology of conscious experience: new perspectives in substance addiction.

The FASEB Journal July 1, 2011 Jean-Pierre Changeux, Hans C Lou

We here review experimental findings relevant for the pharmacology of conscious experience, an issue largely neglected in pharmacological research. First, we focus on self-awareness, a pivotal component of conscious experience and its integration within the global neuronal network (GNW), a theoretical concept that unifies convergent approaches on the neural bases of conscious processing. We...

The visionary cure of the addiction war? Ibogaine: social context, subcultural identity, and implications for drug policy

Drugs and Alcohol Today June 17, 2011 James Rodger 5 citations

Purpose Existing treatments for alcohol and substance dependence are of limited efficacy and acceptability to users. Since such dependence is associated with high co‐morbidity and mortality rates, alternative treatments should be urgently evaluated. Ibogaine, a hallucinogenic alkaloid, derived from Tabernanthe Iboga, a plant unique to the rainforests of West Africa, is already associated with a...

Stimulus independence, social cognition and consciousness.

Cognitive Neuroscience June 2011 Jonathan Smallwood

Abstract A consensus emerging from neuroscience is that certain brain regions show activity correlated with stimulus independent (e.g. private) conscious thought and yet are also implicated in public social processes. The fact that systems supporting social processing also exhibit activity with no obvious perceptual referent, can be seen as support for the framework suggested by Graziano and...

The epidemiology and patterns of acute and chronic toxicity associated with recreational ketamine use.

Emerging health threats journal April 15, 2011 Sarbjeet S Kalsi, David M Wood, Paul I Dargan

Ketamine was originally synthesised for use as a dissociative anaesthetic, and it remains widely used legitimately for this indication. However, there is increasing evidence of non-medical recreational use of ketamine, particularly in individuals who frequent the night-time economy. The population-level and sub-population (clubbers) prevalence of recreational use of ketamine is not known but is...

DOI: 10.3402/ehtj.v4i0.7107 (opens in new tab) Full text (opens in new tab) Dependence Ketamine 2-2-chlorophenyl-2-methylamino-cyclohexanone Acute toxicity +4

Recent national trends in Salvia divinorum use and substance-use disorders among recent and former Salvia divinorum users compared with nonusers.

Substance Abuse and Rehabilitation April 1, 2011 Li-Tzy Wu, George E Woody, Chongming Yang et al. 40 citations

CONTEXT: Media and scientific reports have indicated an increase in recreational use of Salvia divinorum. Epidemiological data are lacking on the trends, prevalence, and correlates of S. divinorum use in large representative samples, as well as the extent of substance use and mental health problems among S. divinorum users. OBJECTIVE: To examine the national trend in prevalence of S. divinorum...

DOI: 10.2147/sar.s17192 (opens in new tab) Full text (opens in new tab) Substance use disorder Salvia divinorum use Substance-use disorder Substance use issues +2

Neural Correlates of Ongoing Conscious Experience: Both Task-Unrelatedness and Stimulus-Independence Are Related to Default Network Activity

PLoS One February 14, 2011 David Stawarczyk, Steve Majerus, Pierre Maquet et al. 315 citations

The default mode network (DMN) is a set of brain regions that consistently shows higher activity at rest compared to tasks requiring sustained focused attention toward externally presented stimuli. The cognitive processes that the DMN possibly underlies remain a matter of debate. It has alternately been proposed that DMN activity reflects unfocused attention toward external stimuli or the...

Mindfulness-Action Based Cognitive Behavioral Therapy for concurrent Binge Eating Disorder and Substance Use Disorders.

Eating Disorders 2011 Christine M Courbasson, Yasunori Nishikawa, Leah B Shapira

Individuals with Binge Eating Disorder (BED) often evidence comorbid Substance Use Disorders (SUD), resulting in poor outcome. This study is the first to examine treatment outcome for this concurrent disordered population. In this pilot study, 38 individuals diagnosed with BED and SUD participated in a 16-week group Mindfulness-Action Based Cognitive Behavioral Therapy (MACBT). Participants...

DOI: 10.1080/10640266.2011.533603 (opens in new tab) Full text (opens in new tab) Humans Substance-related disorders Treatment outcome Pilot projects +7

Marijuana dependence: not just smoke and mirrors.

ILAR Journal 2011 Divya Ramesh, Joel E Schlosburg, Jason M Wiebelhaus et al.

Marijuana (Cannabis sativa) is the most commonly used illicit drug worldwide as well as in the Unites States. Prolonged use of marijuana or repeated administration of its primary psychoactive constituent, Δ9-tetrahydrocannabinol (THC), can lead to physical dependence in humans and laboratory animals. The changes that occur with repeated cannabis use include alterations in behavioral,...

Are the effects of cannabis dependence on glucose metabolism similar to schizophrenia? An FDG PET understanding.

Indian Journal of Psychiatry January 2011 Shubhangi R Parkar, Seethalakshmi Ramanathan, Narendra Nair et al.

Cannabis has been associated with transient psychotic states; however, the causal relationship between cannabis and schizophrenia continues to remain a matter of debate. Epidemiological and some biological studies hint at cannabis being an independent risk factor for schizophrenia; this has not been definitively proved. We aimed to understand the patterns of glucose uptake in important brain...

DOI: 10.4103/0019-5545.75552 (opens in new tab) Full text (opens in new tab) Cannabis dependence Fdg PET Interregional relationships Schizophrenia

The neurobehavioral pharmacology of ketamine: implications for drug abuse, addiction, and psychiatric disorders.

ILAR Journal 2011 Keith A Trujillo, Monique L. Smith, Brian Sullivan et al.

Ketamine was developed in the early 1960s as an anesthetic and has been used for medical and veterinary procedures since then. Its unique profile of effects has led to its use at subanesthetic doses for a variety of other purposes: it is an effective analgesic and can prevent certain types of pathological pain; it produces schizophrenia-like effects and so is used in both clinical studies and...

Extended Knowledge and Causal Dependence

PhilPapers (PhilPapers Foundation) 2011 Esteban Céspedes

One of the principal presuppositions in the extended mind account of Clark and Chalmers establishes that extended and non-extended cognitive systems have somehow the same structure and that the distinctions between them can only be superficial. In contrast, this work presents some arguments for the idea that it is possible to find fundamental differences between both, mainly on the basis that a...