Indian Journal of Psychiatry
September 1, 2026
Anand Prakash, Pranab Mahapatra, Jigyansa I. Pattnaik et al.
ABSTRACT Background: The 4–12 week lag period of conventional antidepressants creates critical vulnerability in severe depression, with peak suicide risk during the first month. While ketamine research has focused on treatment-resistant populations, its potential to eliminate this lag period in non-treatment-resistant severe depression remains unexplored. Aims: To evaluate whether add-on...
Indian Journal of Psychiatry
March 11, 2026
Ajay Kumar, Mahendra P. Sharma, Janardhanan C. Narayanaswamy et al.
Background: Cognitive behavior therapy (CBT) involving exposure and response prevention is the gold standard psychotherapeutic intervention for obsessive-compulsive disorder (OCD). However, applying traditional CBT techniques to treat patients with predominant obsessions (POs) without covert compulsions is fraught with problems because of inaccessibility of mental compulsions. In this context,...
Indian Journal of Psychiatry
February 1, 2026
Mahak Aggarwal, Jawahar Singh, Khushpreet Kaur et al.
Major depressive disorder and co-morbid substance use disorder represent a challenging dual diagnosis, characterized by persistent anhedonia, high relapse rates, and poor response to conventional antidepressants. The dextromethorphan-bupropion combination with synergistic glutamatergic and dopaminergic mechanisms provides a new treatment option. We present three male patients with alcohol or...
Indian Journal of Psychiatry
June 1, 2025
Dushad Ram, Akash Mathew
4 citations
Psychological, social, and cultural factors influence the development of dissociative and conversion disorders. India, with its diverse cultural beliefs and socioeconomic disparities, provides a unique setting for studying the clinical presentations of these disorders. This scoping review synthesizes literature on dissociative and conversion disorders in India, focusing on their...
Indian Journal of Psychiatry
June 1, 2025
Ranjan Das, Rajarshi Chakravarty, Varaha V Gantait et al.
4 citations
Treatment resistant depression (TRD) has been identified as non-response to depression with adequate dose and trial of two antidepressant medications of different classes. Near about 30% depressive patients are TRD cases. Olanzapine-fluoxetine combination, rTMS, Intravenous ketamine and Electroconvulsive therapy have been till now studied in TRD. Dextromethorphan-bupropion is a newer...
Indian Journal of Psychiatry
June 1, 2025
Suparna Kumar, Jigyansa Ipsita Pattnaik, Udit Kumar Panda et al.
3 citations
About one-third of obsessive-compulsive disorder (OCD) cases show poor response to first-line treatments. Ketamine's role in modulating glutamate, implicated in OCD pathogenesis, warrants investigation. Four adolescents with treatment-resistant OCD received ketamine infusion (0.5 mg/kg) every other day for six sessions with monitoring using the Children's Yale-Brown Obsessive Compulsive Scale...
Indian Journal of Psychiatry
May 1, 2025
Varsha Sriperambudoori, Siddharth Sarkar, Anju Dhawan
4 citations
While chemsex has been studied in several parts of the world, it has been an under-studied area in India. Anecdotally, use of substances in the context of sexual encounters has been increasing in India, especially in the population of men having sex with men. In the background of limited literature in India, this online survey aimed to assess facets related to chemsex in the country. This...
Indian Journal of Psychiatry
May 1, 2025
Mohammad Asif Sheikh, Thaddeus Alfonso
1 citation
Mindfulness-based interventions have shown promise in alleviating symptoms associated with obsessive-compulsive disorder (OCD) and major depressive disorder (MDD). However, the specific mechanisms that drive these effects, mainly through obsessive beliefs and mental well-being, are seldom examined. To explore the mechanisms by which mindfulness influences symptom severity in adults with...
Indian Journal of Psychiatry
March 1, 2025
Kamlesh Jha, Pankaj Kumar, Yogesh Kumar et al.
3 citations
Panic disorder is associated with autonomic nervous system dysfunction and reduced heart rate variability (HRV). Enhancing HRV may help mitigate symptoms of panic disorder. This study investigated the effects of Rajyoga mindfulness meditation training on HRV in patients with panic disorder. This prospective randomized controlled trial included 110 patients with panic disorder recruited from a...
Indian Journal of Psychiatry
March 1, 2025
Tathagata Mahintamani, Diptadhi Mukherjee, Debasish Basu
Background: Cannabis has been associated with psychopathology since ancient times, but controversies continue despite important advances in the field. This article is the fourth one in our decadal series of review articles that have been providing an update snapshot of the meandering journey of the research findings in this area. Aims: This narrative review of a comprehensive literature search...
Indian Journal of Psychiatry
September 1, 2024
Harsimar Kaur, Chittaranjan Andrade
3 citations
Dear Editor, Ketamine is used off-label for indications ranging from depression to chronic pain. We know of no report of the successful use of oral ketamine, administered without psychotherapy, for complex posttraumatic stress disorder (cPTSD).[1,2] We describe a patient with chronic depression and cPTSD who failed >30 previous interventions but had dramatic and persistent relief from chronic...
Indian Journal of Psychiatry
September 1, 2024
Bhuvana Prakash Vaidya, Sonia Shenoy, Samir Kumar Praharaj
2 citations
Background: The nature of aberrant salience in schizophrenia, whether it is a state or a trait phenomenon, remains unclear. Aim: To assess and compare aberrant salience in patients with schizophrenia at different stages of the illness and to explore its association with symptom severity and medication use. Methods: A total of 113 subjects were included, comprising 83 patients with schizophrenia...
Indian Journal of Psychiatry
October 1, 2023
Anirban Pal, Purnava Mukhopadhyay, Rajasree Biswas et al.
2 citations
In India, the awareness about the psycho-social dimension of chronic pain is minimal among physicians and patients. The research with community-based group therapies (like mindfulness) to address the psycho-social aspects in chronic pain patients remains limited. The aim of this randomized controlled trial was to see the effects of mindfulness on pain intensity, pain catastrophizing, chronic...
Indian Journal of Psychiatry
January 29, 2023
Jahnavis Kedare, Sachin Pradeep Baliga, Adnanm Kadiani
6 citations
INTRODUCTION Dissociative disorders are quite often present in emergency/casualty. Commonly seen presentations in India include dissociative convulsions, motor symptoms, possession states, at times dissociative amnesia, and dissociative fugue. Dissociative identity disorder is a very rare occurrence in the emergency setting. It is challenging to examine a patient with a dissociative disorder in...
Indian Journal of Psychiatry
July 1, 2022
Gokul Raj
3 citations
Sir, Psychedelic studies have reported positive results for depression and anxiety related to cancer and other life-threatening illnesses, treatment-resistant depression, and tobacco and alcohol dependence.[1] Although there are no active psychedelic research studies going on in India, there is growing interest about these substances as evident by numerous social media groups and pages with a...
Indian Journal of Psychiatry
March 1, 2022
Jassar Abdul Jabbar, A. Ayyappan
Twenty first century is witnessing a renewed interest in the area of psychedelic(hallucinogen) research . In western countries ,even though researches were conducted in this area as early as 1930s, subsequent ban on psychedelic molecules across the world due to widespread use and reported side effects halted the prospects of such researches. This presentation seeks to explore the past history...
Indian Journal of Psychiatry
2022
Ravi Prakash Sharma, Ram Kumar Solanki, Suresh Gupta et al.
Background This study investigated Spiritual beliefs in various types of Dissociative disorder(DD). Method Forty-four subjects diagnosed as dissociative disorder with their types according to ICD 10 diagnostic criteria, free of major comorbidities included in the study. Participants completed a self-administered questionnaire, the Spirituality Involvement and Belief Scale revised (SIBS-R) after...
Indian Journal of Psychiatry
May 1, 2019
Amit Jagtiani, H. Khurana, N. Malhotra
15 citations
Background: It is well known that depression improves faster with electroconvulsive treatment (ECT) than with antidepressant medications. N-methyl-D-aspartate-receptor antagonists (ketamine) have been shown to have rapid antidepressant effects when given as an intravenous infusion. Faster recovery with ECT is likely when used with ketamine as anesthetic. Aim: The aim of the study is to compare...
Indian Journal of Psychiatry
2019
Suprio Mandal, VinodKumar Sinha, Nishant Goyal
92 citations
BACKGROUND: Severe depressive disorder is among most debilitating condition. Conventional pharmacotherapy usually takes several weeks (usually 4-12 weeks) to improve symptoms. Ketamine is an N-methyl-D aspartate receptor antagonist having rapid action on depressive symptoms. OBJECTIVES: The effect of subanesthetic dose of ketamine was assessed on depressive and anxiety symptoms. Illness...
Indian Journal of Psychiatry
July 1, 2016
Sravanti L. Sanivarapu
4 citations
1. Osborne TR, Bhugra D. Practical and theoretical interactions of Buddhism and psychiatry: A view from the west. Indian J Psychiatry 2003;45:142-6. 2. Meadows G. Buddhism and psychiatry: Confluence and conflict. Australas Psychiatry 2003;11:16-20. 3. Wallace BA, Shapiro SL. Mental balance and well-being: Building bridges between Buddhism and western psychology. Am Psychol 2006;61:690-701. 4....
Indian Journal of Psychiatry
October 1, 2015
P. Gangdev, Varinder Dua, N. Desjardins
Background: Usually remembered in the context of Narcolepsy-Cataplexy syndrome, isolated sleep paralysis (SP) and hypnic hallucination are widely prevalent and because of the overlap of symptoms with schizophrenia, their identification is important but unrecognized. Aims: To determine the presence of SP and hypnic hallucinations (HH) in people with schizophrenia and schizoaffective disorder...
Indian Journal of Psychiatry
2013
Tapas Kumar Aich
49 citations
Four noble truths as preached by Buddha are that the life is full of suffering (Duhkha), that there is a cause of this suffering (Duhkha-samudaya), it is possible to stop suffering (Duhkha-nirodha), and there is a way to extinguish suffering (Duhkha-nirodha-marga). Eight fold Path (astangika-marga) as advocated by Buddha as a way to extinguish the sufferings are right views, right...
Indian Journal of Psychiatry
2013
H R Aravinda Prabhu, P S Bhat
Study of mind and consciousness through established scientific methods is often difficult due to the observed-observer dichotomy. Cartesian approach of dualism considering the mind and matter as two diverse and unconnected entities has been questioned by oriental schools of Yoga and Vedanta as well as the recent quantum theories of modern physics. Freudian and Neo-freudian schools based on the...
Indian Journal of Psychiatry
2013
S Haque Nizamie, Mohammad Zia Ul Haq Katshu, N A Uvais
Human experience in, health and disease, always has a spiritual dimension. pirituality is accepted as one of the defining determinants of health and it no more remains a sole preserve of religion and mysticism. In recent years, pirituality has been an area of research in neurosciences and both in the nderstanding of psychiatric morbidity and extending therapeutic interventions it seems to be...
Indian Journal of Psychiatry
2011
Satwant Pasricha
18 citations
Psychology is the scientific study of behavior and experience. Para-psychology studies anomalies of behavior and experience, called paranormal experiences. Paranormal phenomena transcend the boundaries of time, space and force. Para-psychology is divided into two main branches: a) extra-sensory perception (ESP) which is the study of communications ostensibly without the known sensory organs...