Substance Abuse and Rehabilitation
2026
Ethan Murphy, Chao Suo, Govinda Poudel et al.
The consumption of cannabinoids is highly prevalent and has been associated with altered structural, functional, and metabolic brain integrity, measured using PET and neuroimaging tools. However, the current neuroimaging evidence has been summarized by distinct modalities that measure different metrics of brain integrity, precluding a comprehensive understanding of the underlying neurobiology....
Substance Abuse and Rehabilitation
2018
Sarah E. Priddy, Matthew O Howard, Adam W. Hanley et al.
Substance use disorders (SUDs) are a pervasive public health problem with deleterious consequences for individuals, families, and society. Furthermore, SUD intervention is complicated by the continuous possibility of relapse. Despite decades of research, SUD relapse rates remain high, underscoring the need for more effective treatments. Scientific findings indicate that SUDs are driven by...
Substance Abuse and Rehabilitation
2016
Falk Mancke, Gintarė Kaklauskaitė, Jennifer Kollmer et al.
Nitrous oxide (N2O), a long-standing anesthetic, is known for its recreational use, and its consumption is on the rise. Several case studies have reported neurological and psychiatric complications of N2O use. To date, however, there has not been a study using standardized diagnostic procedures to assess psychiatric comorbidities in a patient consuming N2O. Here, we report about a 35-year-old...
Substance Abuse and Rehabilitation
November 1, 2013
Jerry Meyer
93 citations
Ecstasy is a widely used recreational drug that usually consists primarily of 3,4-methylenedioxymethamphetamine (MDMA). Most ecstasy users consume other substances as well, which complicates the interpretation of research in this field. The positively rated effects of MDMA consumption include euphoria, arousal, enhanced mood, increased sociability, and heightened perceptions; some common...
Substance Abuse and Rehabilitation
2013
Tabea Schoeler, Sagnik Bhattacharyya
Investigating the effects of cannabis use on memory function appears challenging. While early observational investigations aimed to elucidate the longer-term effects of cannabis use on memory function in humans, findings remained equivocal and pointed to a pattern of interacting factors impacting on the relationship between cannabis use and memory function, rather than a simple direct effect of...
Substance Abuse and Rehabilitation
April 1, 2011
Li-Tzy Wu, George E Woody, Chongming Yang et al.
40 citations
CONTEXT: Media and scientific reports have indicated an increase in recreational use of Salvia divinorum. Epidemiological data are lacking on the trends, prevalence, and correlates of S. divinorum use in large representative samples, as well as the extent of substance use and mental health problems among S. divinorum users. OBJECTIVE: To examine the national trend in prevalence of S. divinorum...
Substance Abuse and Rehabilitation
March 1, 2011
Jih-Heng Li, Vickna Kasinather, Cheung et al.
146 citations
Ketamine, a derivative of phencyclidine that was developed in the 1960s, is an anesthetic and analgesic with hallucinogenic effects. In this paper, the pharmacological and toxicological effects of ketamine are briefly reviewed. Ketamine possesses a wide safety margin but such a therapeutic benefit is somewhat offset by its emergence phenomenon (mind-body dissociation and delirium) and...