ILAR journal

The neurobehavioral pharmacology of ketamine: implications for drug abuse, addiction, and psychiatric disorders.

ILAR journal 2011 Keith A Trujillo, Monique L Smith, Brian Sullivan et al.

Ketamine was developed in the early 1960s as an anesthetic and has been used for medical and veterinary procedures since then. Its unique profile of effects has led to its use at subanesthetic doses for a variety of other purposes: it is an effective analgesic and can prevent certain types of pathological pain; it produces schizophrenia-like effects and so is used in both clinical studies and...