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ILAR Journal

ISSN 1084-2020, 1930-6180

2 papers in the library · publishing 2011

Papers

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The neurobehavioral pharmacology of ketamine: implications for drug abuse, addiction, and psychiatric disorders.

ILAR Journal 2011 Keith A Trujillo, Monique L. Smith, Brian Sullivan et al.

Ketamine was developed in the early 1960s as an anesthetic and has been used for medical and veterinary procedures since then. Its unique profile of effects has led to its use at subanesthetic doses for a variety of other purposes: it is an effective analgesic and can prevent certain types of pathological pain; it produces schizophrenia-like effects and so is used in both clinical studies and...

Marijuana dependence: not just smoke and mirrors.

ILAR Journal 2011 Divya Ramesh, Joel E Schlosburg, Jason M Wiebelhaus et al.

Marijuana (Cannabis sativa) is the most commonly used illicit drug worldwide as well as in the Unites States. Prolonged use of marijuana or repeated administration of its primary psychoactive constituent, Δ9-tetrahydrocannabinol (THC), can lead to physical dependence in humans and laboratory animals. The changes that occur with repeated cannabis use include alterations in behavioral,...