Debates in consciousness science increasingly question whether computational functionalism is sufficient to explain conscious processing. We summarize three core features of the Global Neuronal Workspace (GNW) theory that highlight the multilevel architecture of conscious processing, extending from cellular and molecular mechanisms to large-scale network dynamics. On this interpretation, GNW is...
2025) aimed at enriching the progressive build-up of a valid theory of conscious processing using valuable multicentric experimentation and massive data-sharing open to new analyses (Bryant and Whyte 2025).
We here analyse the question of developing artificial consciousness from an evolutionary perspective, taking the evolution of the human brain and its relation with consciousness as a reference model or as a benchmark. This kind of analysis reveals several structural and functional features of the human brain that appear to be key for reaching human-like complex conscious experience and that...
We here analyse the question of developing artificial consciousness from an evolutionary perspective, taking the evolution of the human brain and its relation with consciousness as a reference model. This kind of analysis reveals several structural and functional features of the human brain that appear to be key for reaching human-like complex conscious experience and that current research on...
Several neuronal mechanisms have been proposed to account for the formation of cognitive abilities through postnatal interactions with the physical and sociocultural environment. Here, we introduce a three-level computational model of information processing and acquisition of cognitive abilities. We propose minimal architectural requirements to build these levels, and how the parameters affect...
We review the central tenets and neuroanatomical basis of the global neuronal workspace (GNW) hypothesis, which attempts to account for the main scientific observations regarding the elementary mechanisms of conscious processing in the human brain. The GNW hypothesis proposes that, in the conscious state, a non-linear network ignition associated with recurrent processing amplifies and sustains...
Even in the absence of sensory inputs, cortical and thalamic neurons can show structured patterns of ongoing spontaneous activity, whose origins and functional significance are not well understood. We use computer simulations to explore the conditions under which spontaneous activity emerges from a simplified model of multiple interconnected thalamocortical columns linked by long-range,...
We here review experimental findings relevant for the pharmacology of conscious experience, an issue largely neglected in pharmacological research. First, we focus on self-awareness, a pivotal component of conscious experience and its integration within the global neuronal network (GNW), a theoretical concept that unifies convergent approaches on the neural bases of conscious processing. We...
Recent experimental studies and theoretical models have begun to address the challenge of establishing a causal link between subjective conscious experience and measurable neuronal activity. The present review focuses on the well-delimited issue of how an external or internal piece of information goes beyond nonconscious processing and gains access to conscious processing, a transition...
Introduction One of the most important challenges of this century is to understand the neural bases of consciousness from the molecular to the highest cognitive level, in other words, to bridge “the hump from neurochemistry to subjective feeling” (Searle, 2000). Yet, due to the complexity of the human brain, it is not anticipated that a single concept, method, or experimental finding will ever...
The question is raised of the relevance of experimental work with the mouse and some of its genetically modified individuals in the study of consciousness. Even if this species does not go far beyond the level of 'minimal consciousness', it may be a useful animal model to examine the elementary building blocks of consciousness using the methods of molecular biology jointly with investigations...
The subjective experience of perceiving visual stimuli is accompanied by objective neuronal activity patterns such as sustained activity in primary visual area (V1), amplification of perceptual processing, correlation across distant regions, joint parietal, frontal, and cingulate activation, gamma-band oscillations, and P300 waveform. We describe a neuronal network model that aims at explaining...